An IL6 variant -174 G-C alters cardiac hypertrophy but not cardiometabolic responses to HFD in mice - npj Metabolic Health and Disease npj Metabolic Health and Disease - An IL6 variant -174 G-C alters cardiac hypertrophy but not cardiometabolic responses to HFD in mice

How do genetic variants of #interleukin-6 (#IL6) contribute to #cardiometabolic disease? With help from Promethion #Metabolic Cages, scientists tested a knock-in mouse model of the IL6 promoter variant #rs1800795. 🧪

buff.ly/GDBusEN

#Respirometry #Metabolism #CVD #HFD

An IL6 variant -174 G-C alters cardiac hypertrophy but not cardiometabolic responses to HFD in mice Chronic elevations in interleukin-6 (IL6) signaling have been shown to exacerbate features of cardiometabolic disease. A common variant in the IL6 promoter (location -174 G/C, identifier rs1800795) is...

How do genetic variants of #interleukin-6 (#IL6) contribute to #cardiometabolic disease? With help from Sable Promethion #Metabolic Cages, scientists tested a knock-in mouse model of the IL6 promoter variant #rs1800795.

buff.ly/GDBusEN

#Respirometry #Metabolism #Inflammation #Adipose #CVD #HFD