A comprehensive view of somatic mosaicism by single-cell DNA analysis. #SingleCell #scDNAseq #SomaticMosaicism @biorxivpreprint.bsky.social 🧪🧬 🖥️
www.biorxiv.org/content/10.1...

Evaluation of whole genome amplification and bioinformatic methods for the characterization of Leishmania genomes at a single cell level - Scientific Reports Scientific Reports - Evaluation of whole genome amplification and bioinformatic methods for the characterization of Leishmania genomes at a single cell level

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More than 5 years ago we embarked on the journey of using #scDNAseq to study genetic heterogeneity in #Leishmania.

www.nature.com/articles/s41...

Functional phenotyping of genomic variants using joint multiomic single-cell DNA–RNA sequencing. #GenomicVariants #SingleCell #scDNAseq #scRNAseq @natmethods.nature.com 🧬 🖥️
www.nature.com/articles/s41...

DelSIEVE: cell phylogeny modeling of single nucleotide variants and deletions from single-cell DNA sequencing data. #scDNAseq #CellPhylogeny #SNV #Indels #GenomeBiology
genomebiology.biomedcentral.com/articles/10....