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Bedtime App–Guided Mindfulness Meditation in Patients With Insomnia: Mixed Methods #feasibility and Acceptability Pilot Study Background: While mindfulness meditation (MM) apps have gained popularity as a tool for promoting sleep, research focusing on bedtime mindfulness practice and app usage is limited. Objective: As the first step toward understanding the efficacy and mechanisms of such bedtime practice and to inform future investigations, the goal of this pilot study was to explore the #feasibility of app-guided bedtime MM practice with both in-lab and at-home physiological and self-report sleep remote assessments. Methods: We conducted a single arm, prospective mixed-methods pilot study that included both standard in-lab sleep studies and remote at-home assessments in individuals with insomnia disorder with self-reported difficulty falling asleep. Participants practiced MM guided by a commercially available smartphone app at bedtime for four weeks. Pre-post assessments included a battery of sleep-related and psychological health questionnaires, objective physiological sleep measures (polysomnography and actigraphy), and daily sleep logs. We also conducted qualitative exit interviews to further assess #feasibility and acceptability. Transcripts were analyzed for dominant themes using inductive and deductive qualitative methods. Results: We recruited 13 participants with chronic insomnia (symptoms ≥3 nights weekly for ≥ 3 months) to complete the study protocol within eight months (retention rate 77%). We were able to collect analyzable physiological and psychometric data with overall completion rates of over 90%. The study was deemed feasible meeting a priori benchmarks including recruitment, retention, completion and adherence. The 10 participants retained in the program had excellent engagement (95% completion of in-lab studies, 100% completion of questionnaires, 91% compliance with use of the app). Our preliminary analysis of subjective measures indicated improvement in sleep quality, insomnia severity, and pre-sleep arousal, including Pittsburgh Sleep Quality Index (PSQI) change of -3.7 (95% CI: -6.7, -0.7), Insomnia Severity Index (ISI) change of -4.5 (95% CI: -7.7, -1.4), Pre-Sleep Arousal Scale (PSAS) change of -7.7 (95% CI: -13.1, -2.3), and trend toward improvement in the Ford Insomnia Response to Stress Test (FIRST) indicated by a change of -2.5 (95% CI: -5.9, 0.9). From qualitative data, we identified domains that inform the #feasibility and acceptability of the study, including (1) barriers to sleep prior to the study, (2) benefits and skills imparted by mindfulness, and (3) feedback on app use. Benefits and skills imparted by mindfulness included: decreased catastrophizing; acceptance and non-reactivity; body awareness and relaxation; self-kindness; awareness of sleep hygiene and bedtime routine; earlier defusing of stress; increased focus and presence; and calm throughout the day. Conclusions: Bedtime app-guided MM as an intervention in patients with insomnia and the hybrid study design with in-lab and at-home assessments is feasible and acceptable. This study informs the design of future clinical and mechanistic research examining app-guided MM to impact insomnia severity and pre-sleep arousal. Clinical Trial: NCT04242771

JMIR Formative Res: Bedtime App–Guided Mindfulness Meditation in Patients With Insomnia: Mixed Methods #feasibility and Acceptability Pilot Study #MindfulnessMeditation #InsomniaHelp #SleepApp #MentalHealth #Wellness

Calm Launches iOS App for Personalized Sleep Support

Calm launched Calm Sleep, a free iOS app syncing with Apple HealthKit that offers a personalized sleep plan; full access to exclusive Sleep Stories costs $69.99 per year. Now on the App Store. getnews.me/calm-launches-ios-app-fo... #calm #sleepapp #ios

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