Mineralocorticoid Receptor Antagonism Reduces Atrial Arrhythmias Post-Cardiac Surgery and Attenuates Atrial Stress Responses to Cardioplegic Arrest Background New postoperative atrial fibrillation (POAF) occurs in about 40% after cardiac surgery. Mineralocorticoid receptor antagonists (MRA) are known to reduce chronic atrial fibrillation (AF) dev...

A Mayo Clinic study shows that preoperative #MRA associated with 40% reduction in POAF/41% lower AF. #snRNA using Singleron product suggests that canrenone added to cardiac preservation solution inhibits pahways related to chronic AF.
 
www.biorxiv.org/content/10.1... www.biorxiv.org/content/10.1...

Biologists discover a new type of control over RNA splicing RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut o...

Biologists discover a new type of control over #RNA #splicing

#spliceosome #U1 #snRNA #LUC7

phys.org/news/2025-02...

New PHAX for snRNA export!
#RNA #snRNA #RNAsky