Researchers present high-quality #haplotype-resolved MHC assemblies for five widely used #TumorCellLines, enabling precise #GeneticProfiling, revealing #aneuploidy patterns, and advancing insights into tumor #immunogenomics. @fudan-university.bsky.social

Read: doi.org/10.1016/j.ge...

Haplotype-resolved assemblies of the MHC region in five widely used tumor cell lines

In this study, scientists characterized the #aneuploidy of the #MajorHistocompatibilityComplex region in five widely used #tumorcelllines -, #A549, #HeLa, #HepG2, K562, and U2OS, providing a comprehensive genetic landscape of this crucial immunological locus. #medsky

#OpenAccess: buff.ly/6S44RFV