@silv24 hi Natalie. Is #twitjc no more?

I can't find a link to Nature's coverage of @twitjournalclub #TwitJC. I'm sure one of you is better at google than I am. @fidouglas

Just was poking around the defunct #TwitJC. @NephJC has almost as many followers as @twitjournalclub, only 30 more to tie!

@twitjournalclub @silv24
Last one from us is the abstract from Cochrane - we expect a change asap!
#twitjc http://t.co/broHvKEUPa

#twitjc
If the Cochrane meta-analysis is updated I strongly suspect it will show clinical equipoise.
What then?

RT @silv24: Don't leave me hanging twitter doctors - this is an important paper #twitjc

Any #FOAMites out there wanting to help Nat?

RT @twitjournalclub: tonight discussing TTG and cardiac arrest. Your host again is @silv24 #twitjc

Top paper about to be discussed..

@twitjournalclub Hi, I'm Natalie - ST5 Emergency Medicine/PEM. Here as long as I can be! #twitjc

+1 RT @DanGosling8: @kidney_boy yes, but if these were not the planned outcomes for the study then they are convenient results. #twitjc

All of my poor analysis are completely my own. #twitjc

FYI all my good analysis comes from @jklm, sharpest nephrologist on twitter. Too quiet though. #twitjc

The mechanism is saved for the discussion bc it is always the most difficult to prove from a RCT. We just know it works, not how. #twitjc

The big one is acetate. The pH of NS is 5.5, Hartmans is 6.5. That is a 10-fold change. Bicarbonate may prevent contrast AKI #twitjc

Why use the first derivative when you can measure some thing closer to the organ. #twitjc

Yes, because the whole theory on chloride is toxic is that it causes renal failure and this is the conventional way to measure it. #twitjc

RIFLE has been validated as a predictor of mortality, hospital LOS, ICU LOS. In this study I want as much sensitivity as possible #twitjc

If I had to fix one thing about the methods, it would be control vs. treat period, not the blinding. #twitjc

+1 RT @taggiemonster: Think blinding didnt matter as much as main outcome is creatinine and not something subjective like pain score #twitjc

The RIFLE criteria have repeatedly been validated. They are recognized measures of acute kidney injury #twitjc

#TwitJC any thoughts 2 how low a Cl soln 1 must have 2 c better results?

Yeah, is half NS safe? #twitjc

Hawthorne effect - Wikipedia

Hawthorne effect: http://en.wikipedia.org/wiki/Hawthorne_effect
Knowing that some on is watching you/measuring you changes behavior #twitjc

one problem with consent is the time it takes, what fluid would you use for initial resuscitation? #twitjc

Better to blind the doctors and randomize individual patients to Chloride rich vs poor solutions. #twitjc

good but not great methodology. Seems like this would suffer from Hawthorne effect #twitjc

You had me at Saline! #twitjc

Page not found – Precious Bodily Fluids

Joel Topf, Nephrologist. Posted on this article here: www.pbfluids.com/2012/10/saline-versus-ri...
#twitjc

RT @GozdeZorlu MT @fidouglas Does the media influence rate of suicides in the population? Intro post for #TwitJC bit.ly/rbaQ1W