Leveraging Viscosity to Unlock the Osteogenic Potential of BMP‐2 Mimetic DWIVA Dynamic interfaces based on supported lipid bilayers demonstrate that the osteogenic potential of the BMP-2 mimetic DWIVA can be harnessed by modulating substrate viscosity. This work highlights that....

Interested in #Mechanobiology #BoneRegeneration and #GrowthFactor mimetics? Check out our paper in Small @wileyonlinelibrary.bsky.social by @finbariii.bsky.social. We show that viscosity unlocks the osteogenic activity of BMP-2 mimetic DWIVA @theglasgowcemi.bsky.social @uofgengineering.bsky.social 🧪

Congrats again!!! Great work @nadiasoulioti.bsky.social @delphe.bsky.social 🥳🥳

Biomechanical and compositional basement membrane defects due to a Col4a1 mutation affect cardiac morphology and function Collagen IV is a major constituent of basement membranes and mutations in the genes COL4A1 and COL4A2 present clinically as a variable, multi-system d…

Really excited to tell you about our paper just out in the journal Matrix Biology.
@erinboland.bsky.social set out to investigate what the impact of basement membrane defects are on adult heart function/biology.
www.sciencedirect.com/science/arti...

In this work my team and co-workers demonstrated a purely mechanically regulated route for #StemCell #Chondrogenesis via engineering of the hydrogels #viscous nature. No #growthfactors needed. Conducted @uofglasgow.bsky.social @theglasgowcemi.bsky.social Funded @ukri.org

Top Viewed Article in Advanced Healthcare Materials in 2023

Great to see that our work on #viscoelastic #hydrogels for #cartilage #TissueEngineering was one of the most-read papers in Advanced Healthcare Materials @mattjwalker.bsky.social @delphe.bsky.social @manlio-tassieri.bsky.social
Check it out here doi.org/10.1002/adhm... 🧪

🧪This is just a teaser. Stay tuned for more information coming soon!
#6thISMB

A screening setup to streamline in vitro engineered living material cultures with the host Engineered living materials (ELMs), which usually comprise bacteria, fungi, or animal cells entrapped in polymeric matrices, offer limitless possibili…

⚠️ Paper Alert ⚠️
Are you thinking of starting co-cultures of Living Materials with mammalian cells? Then give our paper a read on how to find the best culture conditions for both!
www.sciencedirect.com/science/arti...

Turns out bacteria are pickier than mammalian cells 😄
#livingmaterials #science

A practical workflow for cytocompatibility assessment of living therapeutic materials Living Therapeutic Materials (LTMs) are a promising alternative to polymeric drug carriers for long term release of biotherapeutics. LTMs contain livi…

Paper⚠️ Have you wondered how to assess cytocompatibility on #engineeredlivingmaterials? Because they are ever evolving, it's important to follow how time affects their compatibility with the host. Here we propose a workflow just for that. Check it out! www.sciencedirect.com/science/arti...

🔔 The final version of our COBME paper on how #hydrogel platforms with tunable / dynamic #mechanics enhance our understanding of #cancer progression and #fibrosis is out! 🧪

🌺 Thank you @marcocantini.bsky.social @mattjwalker.bsky.social

#tissueengineering

👇
www.sciencedirect.com/science/arti...

🎁🧧🥗We had such a lovely CeMi #Christmas lunch! 🎅🥗🎄
Join our Centre @theglasgowcemi.bsky.social 💝

#mechanobiology
#6thISMB

Hydrogel-based models to study mechanobiology of cell differentiation in cancer and fibrosis

Happy to share our Current Opinion by @mattjwalker.bsky.social and @delphe.bsky.social🧪
We review how advances in dynamic #hydrogel based #mechanobiology platforms are critical to understand disease progression in cancer and fibrosis @elsevierconnect.bsky.social www.sciencedirect.com/science/arti...

Great news! Looking forward to an inclusive meeting of the #Mechanobiology community in #Glasgow

On behalf of the organizing committee (pic below), I'm thrilled to announce the 6th ISMB, the 2026 International Society of #Mechanobiology Meeting in #Glasgow. See you all there! 🧪

#InternationalSocietyMechanobiology #6thISMB

Pic: G. Ciccone, O. Dobre, D. Gourdon, B. Martinac, M. Vassalli

Could you please add me to the #BME and #BioE community? Thanks!

N-cadherin crosstalk with integrin weakens the molecular clutch in response to surface viscosity - Nature Communications The crosstalk between cell-cell and cell-matrix adhesions regulates stem cell fate. Here, the authors reveal a critical role for matrix viscosity in controlling this crosstalk, which they explain via ...

Interested in how #stemcells sense their environment? Check out our work showing how #ECMatrix viscosity regulates #mechanosensing and #differentiation 🧪 Led by @theglasgowcemi.bsky.social @uofglasgow.bsky.social in collaboration with IBEC @natureportfolio.bsky.social
www.nature.com/articles/s41...

Thanks!

A forum for all things related to the cellular microenvironment and its role in health and disease. Spread the voice and drop a message if you want to join!

go.bsky.app/jhvVHF

Hi! Could you please add me to your stem cell biology community?

Hi! Could you please add me to your community?

Hi! I'm a Biomedical Engineer at the University of Glasgow. Could you please add me to the science feed? Here's a link to my staff page www.gla.ac.uk/schools/engi...

Hi! Could you please add me?

Hi! Please could you add me to this community?

Please add me to this community!

Hi! Could you add me to the signal trasduction starter pack?

Hi! Could you please add me to this list?

Hi! Could you add me to your #mechanobiology community?

Hi! Please add me to your #ECMmatrix community

Hi, could you please add me?

Hi Santiago, could you please add me to your starter pack? Thanks!