Trial at @ki.se
👂 10 pts 1-24yo
👂 deaf due to mutant OTOF -> otoferlin protein
👂 AAV delivered OTOF gene into inner ear thru "round window" of cochlea

Study: AAV gene therapy for autosomal recessive deafness 9: a single-arm trial www.nature.com/articles/s41... ($)

#deafness #hearing #geneTherapy

Artemis II crew take 'spectacular' image of Earth The snap was taken aboard the Orion capsule by its commander, Reid Wiseman, as the crew head towards the Moon.

Artemis II crew take 'spectacular' image of Earth

The Move'n'Groove returns in 2026 on Sunday 5/31 in Albany, CA 🎵🏃🏼‍♀️

Four great local BANDS: movengroove.org/bands/

Register for the 5K run/walk/skate: runsignup.com/Race/CA/Alba...

#AlbanyCA #LiveMusic #FreeConcert
#OutdoorConcert #ConcertInThePark
#FunRun #5K #KidsRace #CommunityFitness #eastBay

Walk from Lake Merritt to the Ferry Building? Bay Skyway path could connect Oakland and SF A Bay Bridge bike ride on April 25 seeks to breathe life back into a cherished dream of cyclists and pedestrians. But the price tag has grown to $700 million.

A Bay Bridge bike ride on April 25 seeks to breathe life back into a cherished dream of cyclists and pedestrians. But the price tag has grown to $700 million.

Everything about this week’s record-shattering western heat wave is extreme An astoundingly strong heat wave is not just setting records across the western U.S.—it’s pulverizing them

Really cannot overstate how bonkers the heat wave out West is. Just obliterating records. 🧪

Bluesky Social media as it should be. Find your community among millions of users, unleash your creativity, and have some fun again.

One problem w Bluesky’s drafts functionality is how it interacts w mobile app refreshing. If you’re working on a post Bsky.app, then navigate to a different app—e.g. search the web— then come back to Bsky, the app refreshes & vaporizes the post you were creating, not saving it as a draft like X does

…and the Sky got a little bluer! 🦋

Drafts are essential social media functionality for the kind of post crafting I do that often involves lots of fact checking, hashtag research, & editing prior to posting. Helps juggle multiple posts that aren’t yet fully baked & ready to go.

#socialMedia #Bsky

Also notable from last year: #Wikidata-powered apps showcased by @lydiapintscher.bsky.social — maybe due for an update?
bsky.app/profile/lydi...

Banner ad for "Wikimania" on a Wikipedia article piqued my curiosity: diff.wikimedia.org/2026/01/27/c...

Proposed topic: social media landscape for wiki community — primarily Mastodon & Bluesky? @wikimediafoundation.org & @wikipedia.org stopped posting on X/twitter in early 2025.

#Wikimania

The link to Jesse's 2025 Wikimania page in this Diff blog post is broken (404). Here's a fixed link:

Web3 & Wikimedia: Building a More Open and Decentralized Knowledge Ecosystem wikimania.wikimedia.org/wiki/2025:Pr...

#blockchain #smartContracts #DAOs
#Wikimania @wikimediafoundation.org

You've heard that something is going on with colon cancer. I'm working on a thing...let me know what you think!! Is it helpful? What would you do different?

hankgreen.com/crc

wikipedia turns 25 today! the last unenshittified major website! backbone of online info! triumph of humanity! powered by urge of unpaid randos to correct each other! somehow mostly reliable! "good thing wikipedia works in practice, because it sure doesn't work in theory" - old wiki adage

🌳 During #COVID19 pandemic, I planted live oak saplings along Ohlone Greenway/BART path in #AlbanyCA. They were volunteers relocated from our yard, seeded by our ‘mother’ oak.

I watered them during the drought & protected them from 🦌 & mowers.

Pics of these #CovidOaks here: x.com/trutane/stat...

Comparing cooperative geometric puzzle solving in ants versus humans www.pnas.org/doi/10.1073/... (OA) Tabea Dreyer et al. + Ofer Feinerman ✉️

“complex brains require extensive communication to cooperate efficiently”

#CollectiveCognition #cooperation
Longhorn crazy #ants
#Myrmecology 🐜

Alice Ting Rosettacon keynote 2025 YouTube video by Alice Ting

Video introduction to our new “Conformational Biasing” method for computational design of mutations that bias proteins towards desired conformational states

CB part starts at 14:55

Thanks to Peter Cavanagh and Andrew Xue – amazing graduate students who co-led this work

Nice #OpenScience contribution by @arcadiascience.com

Demo/proof of concept using #Chlamy colony analysis 👇🏼

Notes:
1️⃣ #Chlamydomonas algae here — not to be confused with #Chlamydia bacterium

2️⃣ #Raman spectroscopy — not to be confused with #ramen cuisine 🍜

Interesting study showing how genetic variation can limit antibody therapies, led by the DBM team (Lepore & Jeker) with computational structural analysis from @torstenschwede.bsky.social @biozentrum.unibas.ch

www.biozentrum.unibas.ch/news/detail/...

#PrecisionMedicine #Genetics #AntibodyTherapy

This silver alert has been scrubbed from the CHP Alerts feed on X where it was originally posted ystrdy. Not flagged as “Located” – just deleted. Any idea why they would do that?

Neither CHP nor Vallejo PD are on Bsky but they are on X where I tagged them about this here: x.com/trutane/stat...

Btw, I used Southwest’s feedback form to let them know about this “planet 404” website glitch, so they may eventually address it — which would be easier than re-printing the cups!

#bamboo #ecoFriendly #ecoSky
#singleUsePlastic #singleUsePlastics
#plasticPollution #plastics

Btw, I used Southwest’s feedback form to let them know about this “planet 404” website glitch, so they may eventually address it — which would be easier than re-printing the cups!

#bamboo #ecoFriendly #ecoSky
#singleUsePlastic #singleUsePlastics
#plasticPollution #plastics

Breaking the Plastic Wave 2025 Our analysis also finds that plastic is interconnected with other global challenges, and that solving the plastic pollution problem will have broad implications for improving the health of people, the...

We're drowning in plastic: Plastic pollution will more than double by 2040 without action. But Pew's new report (launched today) shows that we have the solutions to dramatically reduce it. The question is whether we'll act in time. [🧵 1/3]

Environmental Sustainability Initiatives | Southwest Airlines At Southwest Airlines, we pride ourselves in promoting a healthier Planet. Learn about the efforts we are taking to achieve carbon neutrality by 2050

The website thumbnail shown by Bsky says it’s Southwest’s “Environmental sustainability initiative“ page. Googling that, I get the correct URL: www.southwest.com/citizenship/...

Southwest’s website is failing to redirect from the “planet“ URL that’s printed on the cups. Bluesky maybe using a cache?

Environmental Sustainability Initiatives | Southwest Airlines At Southwest Airlines, we pride ourselves in promoting a healthier Planet. Learn about the efforts we are taking to achieve carbon neutrality by 2050

On a recent Southwest flight, I was served a beverage in a bamboo cup that had Southwest.com/planet printed on it.

When I tried to visit that address in a web browser, I got a 404 error on the Southwest website. However, as I’m writing this post in Bsky, it appears to be resolving successfully. 🤔

How Freaked Out Should We Be About All These Small Earthquakes? | KQED We bring together earthquake scientists to answer all your questions and tell us the latest in the science of quakes.

🎙️ON AIR:

We're joined by earthquake scientists, who will answer all your questions and tell us the latest in the science of quakes.

❓What are your earthquake questions — about our area, preparedness, warning systems?

📻 Listen:

For the M4 earthquake on the Hayward fault near the Claremont this past September (9/22), which happened at 3 AM, both me & my wife we’re awakened by the P wave, so we both experienced the S wave when it hit!
bsky.app/profile/trut...

#seismology #HaywardFault
@berkeleyseismo.bsky.social

Fact vs. Fiction:
“You should never run outside or stand in a doorway during an earthquake.”
Let’s break it down. 👇

Illustrations by Jasmina El Bouamraoui and Karabo Poppy Moletsane are licensed under CC0 1.0 creativecommons.org/publicdomain...

I remixed the image by vertically stacking the originally wide horizontal banner format. My new version is still CC0.

@creativecommons.bsky.social

Why should I donate to @wikipedia.org & where does my money go? (FAQ) donate.wikimedia.org/wiki/FAQ#Why...?

I got this nice graphic in a thank you email from @wikimediafoundation.org "...helping us build a world where people everywhere have access to free & fair information"

#OpenAccess #Knowledge

Note that the one repost on X came from me, as well as one of those likes

Taking it at face value, this example suggests that Bluesky is >100x enriched over X for users interested in this topic, which covers the intersection of life science/drug development/bioinformatics/AI

#Bsky #Twitter #Xitter

Interesting X vs Bsky comparison that reflects on userbase science engagement: identical post below by @scifri.bsky.social posted at same time on both X & 🦋 had 10x more reposts & likes on @bsky.app which has about 15x fewer users (40M vs 600M).
#scicomm #sciSky #science 🧬