Congrats to my labmates for their beautiful work!
They describe a new two-component system modulator, SamT, involved in enterobacterial acid stress response.
Make sure to check out the awesome double-hybrid experiment!
A polymerase ribozyme?! Welcome to the RNA world!
Color photograph of Joan Steitz (Joan Argetsinger Steitz), the distinguished American molecular biologist and biochemist renowned for her groundbreaking discoveries in RNA biology, including the identification of small nuclear ribonucleoproteins (snRNPs) essential to RNA splicing. She is pictured in a close-up portrait within a laboratory or research setting, smiling warmly and directly at the camera with an engaging, approachable expression that conveys enthusiasm and expertise. Steitz has gray hair pulled back, striking blue eyes, and is wearing large, elaborate dangling earrings adorned with purple gemstones and metallic accents. She is dressed in a rich purple blouse. The softly blurred background includes scientific elements such as lab benches, equipment, monitors, charts, and partial signage, evoking the environment of her long career at Yale University where she served as Sterling Professor of Molecular Biophysics and Biochemistry. #JoanSteitz #MolecularBiology #WomenInScience #Biochemistry #RNA
Biochemist/molecular biologist Joan Steitz was born #OTD in 1941.
She (& team) figured out how our cells read/use genetic instructions to make proteins. A key person who helped crack the code on RNA—the molecule that acts like a messenger between DNA & and the proteins our bodies need. #WomenInSTEM
How do we change that?
Our latest paper on protein expression and mRNA stability is out!
academic.oup.com/nar/article/...
Check out how to increase your protein output with a simple trick.
Congratulations to first author @Anna Lipońska, it was a great collaboration with the Aalberts group.
#RNAsky #ribosome #EGM
🫳 Metastable folding of Bacillus subtilis glmS ribozyme modulates turnover by RNase J1:
www.sciencedirect.com/science/arti...
#subtiwiki
In this study, we highlight the importance of the base composition of the first codons for protein expression. An increased abundance of adenine (A) and a decrease in guanine (G) enhance expression and improve mRNA stability. The mediator of this effect is the ribosome.
Standing on the shoulders of giants. Researchers (nodes) at early (red), mid (blue) and late (grey) career stage who have built on one another's work (edges). Large nodes are researchers whose work would not be recognized with journal level metrics but would be recognized with article level metrics. Credit: B. Ian Hutchins
Are authors fairly judged by assessing the #journals in which their work is published? @bihutchins.bsky.social &co reveal that most influential papers are published in lower tier journals, and more authors would be better recognized with #ArticleLevelMetrics #ALMs @plosbiology.org 🧪 plos.io/4oV58Ed
DusB links tRNA modification with oxydative stress response in V. cholerae! Congrats to @zeynepbaharoglu.bsky.social and colleagues!
RNA–RNA interactome approaches provide in vivo evidence for a critical role of the Hfq rim face in sRNA–mRNA pairing url: academic.oup.com/nar/article/...
Here I thought that this word described whatever I am doing with pancakes and french toast on sunday mornings!
An rRNA modification to adapt translation to anaerobic conditions!
Félicitations!!
The EMBO Gold Medal 2025 was awarded to Tanmay Bharat and David Bikard: www.embo.org/press-releases/embo-gold... 🧪
At #CellBio2025, the EMBO Gold Medal was handed over to David Bikard in recognition of his pioneering work on #GeneEditing.
Exametabolomics!
© Bayerische Staatskanzlei
Today, Minister-President Markus Söder awarded @jorg-vogel-lab.bsky.social the Bavarian Maximilian Order. Presented every two years, the award recognizes outstanding accomplishments in science & the arts and is regarded as one of the state’s highest honors. Congrats on the “Bavarian Nobel Prize”! 👏🎉
Very cool paper, studying mechanisms (and a toxin) targeting the ribosome, translation initiation and the use of Shine-Dalgarno motifs!
This is so photogenic!
BREAKING: Friday night massacre underway at CDC. Doznes of "disease detectives," high-level scientists, entire Washington staff and editors of the MMWR (Morbidity and Mortality Weekly Report) have all been RIFed and received the following notice:
Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here:
emploi.cnrs.fr/Offres/Docto...
Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.
hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!
Communiqué de presse : financement de la recherche publique : la communauté scientifique alerte sur un système à bout de souffle. #veilleESR, @info.gouv.fr @agencerecherche.bsky.social @cnrs.fr @franceuniversites.bsky.social @inserm.fr @inrae-france.bsky.social @enseignementsup-recherche.gouv.fr
Congrats to @mlejars.bsky.social for this really cool publication!
Tired of your somewhat easy life doing genetics in E.coli? Make it even way easier with Maxence's method!!
Truely beautiful work!
So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!
Exciting FULL PROFESSORSHIP at the Vienna BioCenter - Molecular Mechanisms of Disease Mechanisms: www.maxperutzlabs.ac.at/news/open-po... Come be our colleague!
Many congrats to Ninon Christol from our Microbial Gene Expression research unit, IBPC CNRS, as well as to @maximiliankohl.bsky.social from IBMC at Univ. Strasbourg, for their amazing poster prizes!
I am glad you enjoyed it!
Thanks a lot!