RESEARCH PAPER: tRNA synthetase activity is required for stress granule and P-body assembly
By Baymiller et al. and Stephanie Moon
➡️ https://genesdev.cshlp.org/content/40/7-8/475.full

Stephanie Moon
#translation #ribosome #granule #stress

Eukaryotic ribosomes also hibernate and SNORe.. identification of a new hibernation factor in yeast and fungi, which interacts with rRNA #ribosome 💫

🆕 ADVANCE ONLINE 🆕

RESEARCH PAPER: tRNA synthetase activity is required for stress granule and P-body assembly
By Baymiller et al. and Stephanie Moon
➡️ genesdev.cshlp.org/content/early/2026/01/13...

Stephanie Moon
#translation #ribosome #granule #stress

Proud to share our latest preprint! 🥳
Using a multidisciplinary approach, we uncover a dual function of the snR37 H/ACA snoRNP - combining pseudouridylation with ribosome chaperone activity within a single RNP.🔬🧬
Challenging the traditional view of snoRNP function. 👇
#cryoEM #ribosome #RNA #snoRNA

"Dynamics of A-Minor Interactions in the Bacterial Ribosome"

Christian Steinmetzger (@stonebutcher.bsky.social) talked at #Biochemistry2026 about his work on this topic in the group of @katjapetzold.bsky.social.

#Biochemistry #Ribosome #ChemSky #ChemBio #NMR
CC: @gdch.de

How can nature make #peptides covering chemical space beyond the proteinogenic amino acids using the #ribosome?

Wilfred van der Donk talked at #Biochemistry2026 about the power of ribosomally-synthesized and post-translationally modified peptides #RiPPs.

pubs.rsc.org/en/content/a...
#Biochemistry

The selfish ribosome The ribosome is responsible for protein synthesis in all cells, and is the largest energy consumer in the cell. We propose that the ribosome originated as a mutualistic symbiont of an RNA-dependent RN...

On #ribosome addiction and early life 🌌 arxiv.org/abs/2602.23268 by @mkrupovic.bsky.social

Ribosome transfer via tunnelling nanotubes rescues protein synthesis in pancreatic cancer cells - Cell Communication and Signaling Cell Communication and Signaling - Pancreatic ductal adenocarcinoma (PDAC) is considered as one of the deadliest types of cancer. Tunnelling nanotubes (TNTs) are thin, membranous, intercellular...

Huh? 😱 #Ribosome #RNASky cell-to-cell ribosome/r-proteins transfer?!
link.springer.com/article/10.1...

"The collision propensity of specific #ribosome subpopulations increases with molecular age."

#Ribosome #RNASky Aged ribosomes do not elongate well on positively charged residues

Spring is almost here 🌸 and so is conference season!

🔬 RNA Leaders
📅 Mar 17–19 | 📍 Vienna
Meet our CEO, Max, to discuss ribosome profiling & tRNA-seq solutions.

🔬 RNA Club Rhineland
📅 Mar 27 | 📍 Bonn
Our Sales Director Lutz will be in the Rhineland area from Mar 25–28.

#RNA #Ribosome #tRNAseq

rRNA expansion segments mediate hibernating ribosome formation. www.science.org/doi/10.1126/... and www.biorxiv.org/content/10.6... #Ribosome 🧪

1/4 Our preprint “Modulation of the RNase P/MRP complex and mitochondrial ribosome enhances cytosolic ribosome coordination and sustains longevity” is now live @biorxivpreprint.bsky.social 📄 #agingbiology #ribosome 👉www.biorxiv.org/content/10.64898/2026.02...

The #ChlamyDataset has now been used to elucidate the protein extensions of the #chloroplast #ribosome 💚

🧵 🔽 an explanation for the extra extension in the chlororibosomal proteins #Ribosome #RNASky 🧪

Which ribosomal subunit does chloramphenicol target? 🧫💊 #ribosome #chloramphenicol #pharmacology ... Continue to: www.youtube.com/watch?v=-SBl...

🧬 RNA Modifications Newsletter – February 2026 ⛸️ issue #8

⛸️🧬 February RNA Modifications Newsletter

From CRISPR-triggered tRNA tail cleavage to temperature-responsive rRNA modifications, ribosome QC, and pathway-specific rRNA modification during biogenesis.
#RNAmods #Epitranscriptomics #Ribosome #Translation #tRNA #rRNA

What is wrong with your mRNA drug? Is it the UTR? The ribosome?
With ReCet, our reconstituted cell-free translation system, you can test ribosomes, cytoplasm, and mRNA independently—and get results in ~1 hour via luciferase or WB. Learn more: zurl.co/3Evlj

#ribosome #mRNA #cellularbiology

Archaeal Arc-P & Arc-A ribosome hibernation factors from deep-sea methanogen Methanolobus #ribosome #RNASky

Archaeal ribosome hibernation factors on the roll lately, check out the SriA, C; SirB, D with distinct ribosome binding #ribosome #RNASky

The Employee Spotlight is back! ✨
Meet Michele, our Tech Support Specialist. With a PhD in Biomolecular Sciences and deep RiboSeq expertise, he’s more than just tech support— he's an all-round scientist and a patient teacher in our practical workshops. Get to know him! #ribosome #employeespotlight

The DinG exonuclease acts as a primary quality controller to remove unprocessed ribosomal RNAs Abstract. Bacteria lacking DEAD-box RNA-helicases often show reduced growth and aberrant maturation of ribosomal subunits resulting in fewer active ribosom

#RNAsky #RNAbiology #ribosome 🦠

Mechanistic insights into E. coli recovery from growth arrest Bacteria survive hostile conditions in clinically relevant conditions by shutting down protein synthesis, but how they restart growth remains poorly understood. Here, we use an E. coli delta-rimM stra...

Role of RimM ribosome maturation factor in recovery after protein synthesis arrest 🦠 #ribosome #rnasky #rnabiology

We’re starting 2026 on the road 🧬
Meet Davide this month at RNA Workshop (Bern) and RNA UK 2026 (Windermere)!
Come chat translatomics, discover our solutions, and grab some Immagina gadgets 😎

#RNA #Translatomics #Ribosome

Proximity-specific ribosome profiling reveals the logic of localized mitochondrial translation Development of LOV-domain-controlled ligase for translation localization (LOCL-TL), an optogenetic approach for monitoring translation with codon resolution at any defined subcellular location under p...

Proximity-specific ribosome profiling #ribosome #rnabiology in mitochondria
www.cell.com/cell/fulltex...

RNA Modifications Newsletter - January 1st, 2026 - Winter Edition ❄️ Issue #7 - Happy new year!

🧬❄️ RNA Modifications Newsletter - Jan 2026 is out!
RNA mods, ribosome remodeling, codon effects, nanopore detection, translation under stress - winter edition

❄️🧫From hypoxia-driven rRNA methylation to tRNA-linked virulence and ribosome structure.
#RNAsky #RNAbiology #Ribosome #microsky

Evolution of the ribosomal exit tunnel through the eyes of the nascent chain The ribosomal exit tunnel is a universally conserved feature of the large subunit that directs the nascent polypeptide chain into the cellular environment and is involved in co-translational folding, ...

Just in time for 2026! 🎆 Presenting a nascent-centric view on the shape of the ribosomal exit tunnel topology, based on MD-derived occupancy maps for 55 distinct ribosomes. 🧶🧬🖥️
📄 Read the preprint: biorxiv.org/content/10.6...

#StructuralBiology #Ribosome #CryoEM #Evolution #Biophysics

How medically important antimicrobials bind to the 30S ribosomal subunit in a bacterial pathogen Ribosomes translate the genetic code in mRNA to synthesize proteins in all living organisms. Decoding of mRNA occurs in the small subunit of the ribosome and is mediated by tRNA anticodons. Regions ne...

1/ Our new preprint is out on biorxiv on how antibiotics bind to bacterial 30S subunits, please repost. #ribosome #antibiotics #microsky #rnasky doi.org/10.64898/202...