#RNAsky

The Landscape and Regulatory Determinants of A-to-I RNA Editing in Escherichia coli and Pseudomonas aeruginosa Isolated From Patients With Urinary Tract and Ear Infections Here, we describe the occurrence, regulatory features, and predicted effect of RNA-specific sequence changes resulting from A-to-I RNA editing in E. coli a

doi.org/10.1093/infd... A to I editing in clinical isolates during infection 💫🦠 #UTI #microsky #rnasky

#RNAsky #RNAbiology

Validate User

Mistranslation from an endogenous tRNA variant in human pan-genome cell lines doi.org/10.1093/nar/... " a natural genome-encoded human tRNA mutant causes mistranslation in cells derived from healthy individuals" with impact on modification and fragmentation
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#RNAsky #RNAbiology #ViroSky #VirEvol

#RNAsky #RNAbiology

#RNAsky #RNAbiology

Purification of post-transcriptionally modified tRNAs for enhanced cell-free translation systems Abstract. Transfer RNAs (tRNAs) are utilized by the ribosome to decode the nucleic acid alphabet. tRNA structure, stability, aminoacylation efficiency, and

Purification of native tRNAs from E. coli with their post-transcriptional modifications and translational activity 🦠 #rnasky #rnabiology academic.oup.com/nar/article/...

#RNAsky

#RNAsky

#RNASky #RNAbiology

Ribosome transfer via tunnelling nanotubes rescues protein synthesis in pancreatic cancer cells - Cell Communication and Signaling Cell Communication and Signaling - Pancreatic ductal adenocarcinoma (PDAC) is considered as one of the deadliest types of cancer. Tunnelling nanotubes (TNTs) are thin, membranous, intercellular...

Huh? 😱 #Ribosome #RNASky cell-to-cell ribosome/r-proteins transfer?!
link.springer.com/article/10.1...

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#Ribosome #RNASky Aged ribosomes do not elongate well on positively charged residues

Connect with researchers in #GeneRegulation, small RNAs, #StructuralBiology and more at the EMBO Workshop "RNA-guided genome protection" in #Caux, CH, 16–20 June 2026.

Deadine: 15 March

https://meetings.embo.org/event/26-genome-protection
#DNAsky #RNAsky #EMBORNAGenomeProtection #EMBOevents 🧪

Control of retrotransposon-driven activation of the interferon response by the double-stranded RNA binding protein DGCR8 Abstract. The type I interferon (IFN) response is the main innate immune pathway against viruses in mammals. This pathway must be tightly regulated to prev

I'm so happy to share our latest paper! Now out in @narjournal.bsky.social 🥳

Did you know that transposable elements embedded in mRNAs can form dsRNA and activate innate immunity? 🧬🦠 Have a look! academic.oup.com/nar/article/...

#TEsky #RNAsky #RNAbiology #immunity #NAR

codon usage About the Conference Codon usage bias—the preference for certain synonymous codons—is a key factor in genome regulation. Codon usage and synonymous codon mutations have been shown to influence gene ex...

Just a reminder - Please Register for the 3rd Codon Usage Conference in Montreal, Canada from May 31- June 3, right after the RNA Society Meeting.

Even if you can't go, please share! #RNA #RNAsky #RNAbiology

sites.google.com/view/codonus...

Great to see our review on ADAR1 and dsRNA sensing out in ATVB @ahascience.bsky.social today! Our understanding of the ADAR1-dsRNA-MDA5 axis in complex and rare disease is changing rapidly with important implications for therapy --> worth a read. #RNAsky
www.ahajournals.org/doi/10.1161/...

Global dissemination of npmA mediated pan-aminoglycoside resistance via a mobile genetic element in Gram-positive bacteria - Nature Communications The authors investigate the distribution of the aminoglycoside resistance gene npmA in Gram-positive bacteria via a mobile genetic element, highlighting its global presence and cross-species transfer ...

multi resistance dissemination with rRNA modification enzyme on mobile genetic element 🦠 #AMR #RNAbiology #rnasky

#RNASky #RNAbiology

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#RNAsky 🤩🤩🤩🤩🤩🤩🤩

Join us tomorrow (Feb 19) for a live discussion on overcoming key limitations in conventional #RNASeq, including incomplete transcript capture and structural bias, and exploring newer approaches that improve data resolution and confidence.

Register via the link in the comments.

#RNA #RNASky

#RNAsky

Decoding RNA–protein interactions using high-throughput methods RNA-binding proteins (RBPs) constitute a diverse class of proteins essential for every stage of the gene expression process. Many RBPs are also linked to human diseases and pathologies. Understandi...

Happy to share the first review article from our lab!

We discuss the landscape of available high-throughput approaches for profiling RNA–protein interactions in vitro and in vivo.

We hope it will be useful when designing your next experiment.

www.tandfonline.com/doi/full/10....

#RNAsky

#RNAsky

Do you want to understand how RNA #splicing decisions are made? We‘ve got a PhD position open for you (see 👇👇)!!
Please share #RNAsky and RT!

tinyurl.com/4ztu9cb9

🧵 🔽 an explanation for the extra extension in the chlororibosomal proteins #Ribosome #RNASky 🧪

#RNAsky

I’m super excited to be opening a lab at WEHI. We’ll be focussing on how double-stranded RNA is regulated in cells, how failures in these pathways drive disease and new therapies to manipulate inflammatory responses to RNA.

#newPI #RNAsky