The biggest sustainability challenges are rooted in biology we’re still learning to understand. Hi-C helps build better genomes and unravel microbial communities that support healthier soils, stronger crops, and more resilient ecosystems. Happy 🌎 Day from Phase Genomics.
Long reads get you contigs. Proximo™ Hi-C Kits for Plants get you chromosomes you can put to work or meaningful trait / QTL mapping and functional analysis.
Tell us about your research and take 20% off through May 1👇
info.phasegenomics.com/hi-c-plant-g...
One oat line has more structural variation than a panel of wheat lines. That finding, from the 1st chromosome-scale oat assembly, led to a 30-line hexaploid oat pangenome published in @nature.com using HiFi + Hi-C.
Full breakdown from senior author Jeff Maughan, PhD, in the clip below:
Your research budget just got a little more room to grow. Take 20% off Proximo™ Hi-C Kits for plant genomics until May 1st.
Hi-C unlocks chromosome-scale insights from your long reads. Get started here 👇
info.phasegenomics.com/hi-c-for-plants
New in the Journal of Water and Health: ProxiMeta™ Hi-C metagenomics improves antimicrobial resistance tracking in wastewater.
Key findings:
→ 2,816 traits detected
→ 554 genes linked to hosts
→ 52.9% of genes were ARGs
🔗 iwaponline.com/jwh/article/...
32% off ProxiMeta™ Hi-C kits ends 3/15 (then save 16% through end of month).
You’ll get:
✅ High-quality MAGs from complex samples
✅ More complete genomes than traditional binning
✅ Accurate host attribution for phages, plasmids, and AMR genes
👉 info.phasegenomics.com/march-magness
March MAGness is here! Score special pricing on ProxiMeta™ Hi-C kits for metagenomics & microbiome studies in everything from complex soil samples, to gut microbiomes, to bioreactors:
🔬 32% off | March 2–15
🔬 16% off | March 16–31
Get started here 👇
info.phasegenomics.com/march-magness
FISH finds what it's looking for, and only what it's looking for. In a new study in @AjHematologyshows, Hi-C confirmed FISH findings, plus chromothripsis, CN-LOH & complex rearrangements that FISH probes can’t pinpoint.
🔗onlinelibrary.wiley.com/doi/epdf/10.1002/ajh.702...
New Nature Plants study using Proximo™ Hi-C shows how a hybrid eelgrass species inherited low-light tolerance genes from its deep-water parent that could change how we approach coastal restoration.
More from Todd Michael, PhD & team at @salkinstitute.bsky.social l 📄 www.nature.com/articles/s41...
New Publication in @plosbiology.org: Optimized Hi-C analysis (Z-score filtering) boosts specificity & reveals virus-host interactions using Phase Genomics’ ProxiMeta™ Hi-C: 79 genus-level matches + 293 new linkages in well-studied, climate-critical soils.
journals.plos.org/plosbiology/...
"A year and a half ago, we couldn't have resolved this hybrid genome."
New tech (long reads + Hi-C) let researchers separate parental haplotypes in eelgrass revealing which genes drive low-light tolerance. Todd Michael, PhD breaks down how:
Phase Genomics IRL: a few days together in Portland for real-time collab & creativity. Aligning on new products, pressure-testing ideas, a little fun behind the wheel. It’s how we build even better Hi-C tools for the researchers who rely on them.
A few of our favorite moments👇
Tissue prep drives variability early in Hi-C workflows. A new STAR Protocol adds cryogenic tissue grinding before crosslinking, with safe pause points for optimized lab workflows.
See how it improves reproducibility & library quality → star-protocols.cell.com/protocols/4702
Wheels up ✈️ Our CEO Ivan’s headed to Newport Beach for Microbes in Wastewater.
He’ll show how ProxiMeta™ links microbes, phages & the mobilome to track #AMR in wastewater. No coding. Just discovery. If you’ll be in Newport for the conference, say hi to
@ivanliachko.bsky.social
We heard you. Our 25 in ’25 promo is extended through Jan 16.
Save 25% on Phase Genomics Hi-C kits via direct order, book a complimentary bioinformatics consult, and access discounted full-service ProxiMeta™ packages.
Get started → info.phasegenomics.com/25-in-25
Bees carry more than nectar. Their gut microbiomes buzz with plasmids, sharing tetracycline resistance genes across hives. Chris Robinson, PhD from Irene Newton, PhD’s lab used Hi-C to track these mobile elements & explore colony-specific patterns traditional metagenomics misses.
Stuck on Hi-C data? First 25 researchers to email get a free consult with our computational scientists—whether you're using our kits or another provider's.
Email info@phasegenomics.com with "25 in '25 Bioinformatics Promo" in the subject line to claim yours.
Save 25% on Hi-C kits through Dec 31. From complex plant genomes to metagenome binning, Phase Genomics brings clarity to your toughest research questions. Email info@phasegenomics.com with "25 in '25 Kit Promo" in the subject line to claim your discount.
🌿 Scientists produced a high-quality, chromosome-scale genome for American pickleweed, a salt-loving, tetraploid marsh plant. With ~80k genes and detailed methylation data, this resource paves the way for understanding salt-tolerance & supporting salt-marsh conservation.
🔗 bit.ly/3XAQ7vT
New at #AMPath2025: He Fang, PhD, will showcase Genomic Proximity Mapping® (GPM) and CytoTerra® in #sarcoma.
Stop by Level 2, 258ABC on 11/13 from 2:30 – 3:30 pm ET to discover how GPM uncovers hidden structural variants and mosaicism in challenging archival samples.
🌿 New in @NaturePlants! Researchers used Phase Genomics’ Hi-C to build a haplotype-resolved chromosome-scale #genome of a hybrid eelgrass (Zostera marina × Z. pacifica), revealing genomic clues to low-light tolerance that could boost coastal restoration. www.nature.com/articles/s41...
Big spotlight on Genomic Proximity Mapping® (GPM®) from Elsevier's JMD: See how UW researchers use our GPM platform, CytoTerra®, to detect cryptic structural variants and mosaicism missed by standard tests. Full press release from @elsevierconnect.bsky.social: www.elsevier.com/about/press-...
Phase Genomics Hi-C helped untangle the pomegranate genome, ordering contigs into chromosome-scale scaffolds, clarifying chromosome counts & revealing domestication patterns. Full study from the Volcani Center: link.springer.com/article/10.1...
Phase Genomics’ Hi-C tech helped undergrads assemble the “best duckweed genome yet,” giving them hands-on research experience, boosting PhD prospects, and advancing plant biology. Full story from Alex Harkess at HudsonAlpha on YouTube: na2.hubs.ly/H01P7mG0
Hi-C at scale is reshaping plant biology. With Phase Genomics’ kits, Alex Harkess & HudsonAlpha have published dozens of genomes, uncovered how rising CO₂ alters chromatin structure, and explored how climate change ripples through living systems. 🔗 youtu.be/5-Ub7FnpHzs?...
Happy #WorldPhageDay.
Tiny, abundant, and anything but boring, phages shape microbial communities, move genes around, and can tip the balance in all kinds of ecosystems.
The catch: to know a #phage only you must know its host. ProxiMeta Hi-C technology gives us that link.
🌳 New chromosome-level Ulmus minor (field elm) genome unlocks clues to Dutch elm disease resistance. Using long reads and Hi-C, the team built this 2.1Gb genome and mapped clusters of resistance genes conserved across elm species to aid restoration.
na2.hubs.ly/H01HQ2Q0
ProxiMeta™ Hi-C fills the missing link in shotgun metagenomics, connecting viruses to hosts & revealing hidden microbial relationships. Hear more from Phil Hugenholtz & Phase Genomics CEO Ivan Liachko on how Hi-C unlocks the microbiome → www.youtube.com/watch?v=DYMv...
Skip the computational guesswork. Hi-C / proximity ligation reveal complete chromosomal architecture based on actual intracellular contacts.
From plant genomes to metagenomes, Phase Genomics delivers chromosome-scale assemblies traditional methods can’t: phasegenomics.com/resources-an...
