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Posts by grumpyhobbit

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Changing of the guard!
#roc #peregrine #falcon

1 week ago 1020 82 7 2
Rows of tulips in a field

Rows of tulips in a field

Tulip fields at the Roozengaarde, Mt Vernon, Washington🌷
📸George Mamar

1 week ago 942 80 17 2
Abstract
Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disorder, characterized by symptoms such as post-exertional malaise (PEM) and cognitive impairments. This study assessed reaction time (RT) metrics in three-dimensional (3D) visual tasks with the aim of objectively quantifying the cognitive impairments in ME/CFS patients compared to controls. Methods: A total of 120 participants (60 ME/CFS patients and 60 controls) were recruited at the Department of Ophthalmology, Universität of Erlangen-Nürnberg. RT was assessed using a virtual reality–oculomotor test system, presenting 3D stimuli at three disparity levels (275″, 550″, and 1100″) within three gaming repetitions (R1, R2, and R3). Mixed-effects models were used to evaluate group differences, with age and gender as covariates. Pairwise contrasts were calculated to assess changes across repetitions. Fatigue self-assessments were recorded by validated questionnaires, (FACIT Fatigue Scale, Chalder Fatigue Scale, Bell Score and Health Assessment Questionnaire), and their correlation with RT metrics was portrayed using a Spearman correlation matrix. Results: Estimated means (EM-means) for RT were significantly prolonged in ME/CFS patients compared to controls at disparity 275″ (1969 ms vs. 1384 ms; p = 0.0001), 550″ (1409 vs. 1071 ms; p = 0.0012) and 1100″ (1126 ms vs. 891 ms; p = 0.00223). Age was a significant covariate (p < 0.001), while gender showed no effect. Both groups demonstrated improvements in RT over repetitions; however, ME/CFS patients showed a significantly lower improvement compared to controls, reaching significance in R3 (p = 0.0042). RT metrics did not correlate with patients’ self-assessment scores. Conclusions: ME/CFS patients showed consistently slower RTs compared to controls, particularly in later, easier gaming repetitions, potentially reflecting the impact of fatigue.
Keywords: ME/CFS; post-exertional malaise; PEM; reaction time; 3-dimensional; Pos…

Abstract Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disorder, characterized by symptoms such as post-exertional malaise (PEM) and cognitive impairments. This study assessed reaction time (RT) metrics in three-dimensional (3D) visual tasks with the aim of objectively quantifying the cognitive impairments in ME/CFS patients compared to controls. Methods: A total of 120 participants (60 ME/CFS patients and 60 controls) were recruited at the Department of Ophthalmology, Universität of Erlangen-Nürnberg. RT was assessed using a virtual reality–oculomotor test system, presenting 3D stimuli at three disparity levels (275″, 550″, and 1100″) within three gaming repetitions (R1, R2, and R3). Mixed-effects models were used to evaluate group differences, with age and gender as covariates. Pairwise contrasts were calculated to assess changes across repetitions. Fatigue self-assessments were recorded by validated questionnaires, (FACIT Fatigue Scale, Chalder Fatigue Scale, Bell Score and Health Assessment Questionnaire), and their correlation with RT metrics was portrayed using a Spearman correlation matrix. Results: Estimated means (EM-means) for RT were significantly prolonged in ME/CFS patients compared to controls at disparity 275″ (1969 ms vs. 1384 ms; p = 0.0001), 550″ (1409 vs. 1071 ms; p = 0.0012) and 1100″ (1126 ms vs. 891 ms; p = 0.00223). Age was a significant covariate (p < 0.001), while gender showed no effect. Both groups demonstrated improvements in RT over repetitions; however, ME/CFS patients showed a significantly lower improvement compared to controls, reaching significance in R3 (p = 0.0042). RT metrics did not correlate with patients’ self-assessment scores. Conclusions: ME/CFS patients showed consistently slower RTs compared to controls, particularly in later, easier gaming repetitions, potentially reflecting the impact of fatigue. Keywords: ME/CFS; post-exertional malaise; PEM; reaction time; 3-dimensional; Pos…

New from Germany

3D Virtual Reality Performance Metrics as a Future Fatigue Biomarker in Myalgic Encephalomyelitis/Chronic Fatigue
Syndrome (ME/CFS)

www.mdpi.com/2227-9059/14...

#MEcfs #PwME

1 week ago 8 3 1 0
Video

Yesterday morning was peak Saguaro! 🌵 🌼 (13 blossoms?!)

1 week ago 6829 778 176 31
Illustration off some sharks but they are based on citrus. Lemon sharks are real the others are just for fun heh

Illustration off some sharks but they are based on citrus. Lemon sharks are real the others are just for fun heh

dose of vitamin sea 🍋
#art #sharks

1 week ago 2962 900 14 4
Male Indian Golden Oriole (Oriolus kundoo)...their appetite for caterpillars and beetles helps manage insect populations in the tree canopy. A profile view of a vibrant, bright-yellow songbird perched on a textured tree branch. It has solid black wings, a black tail, and a distinct black streak extending through its eye. Its sharp, pointed beak is a pale reddish-pink, and it is looking upward toward green leaves.

Male Indian Golden Oriole (Oriolus kundoo)...their appetite for caterpillars and beetles helps manage insect populations in the tree canopy. A profile view of a vibrant, bright-yellow songbird perched on a textured tree branch. It has solid black wings, a black tail, and a distinct black streak extending through its eye. Its sharp, pointed beak is a pale reddish-pink, and it is looking upward toward green leaves.

Male Indian Golden Oriole (Oriolus kundoo)...their appetite for caterpillars and beetles helps manage insect populations in the tree canopy. #birds #wildlife #photo #ecology #nature

1 week ago 1673 135 14 3
Preview
Surprise RNA Discovery Challenges Long-Held Beliefs About How Genes Work Scientists have identified a new RNA molecule that may play a key role in improving survival in cancer patients.

scitechdaily.com/surprise-rna...

1 week ago 7 2 0 0
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Vermilion Flycatcher (Pyrocephalus rubinus): A 14cm (5.5in) bird that bucks the trend of Flycatcher species mostly having what is described as "drab" plumage! Found in open country, they feed on insects often flying from a perch & catching mid-air. Photo by Banook Rodarte in Yuma, Arizona, USA #bird

1 week ago 2009 170 15 6
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A little mid-weight reading

1 week ago 12 1 1 0
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An orphaned baby kangaroo needs our help to survive. These little joeys are vulnerable and require constant care and love after losing their mothers.

1 week ago 7546 1008 149 61
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Lita Lacson, contemporary Filipina artist.

"Tomorrow in Yellow."

"Watercolor."

1 week ago 4801 477 90 20
Bhumisparsha Mudra (Earth Witness) Buddha statue .  Seated, with left hand remaining on dhyana mudra with cat, asleep.

Bhumisparsha Mudra (Earth Witness) Buddha statue . Seated, with left hand remaining on dhyana mudra with cat, asleep.

Taking refuge🪷

1 week ago 8037 814 80 33
Video

A less than regular visitor came by this afternoon, a male Costa’s hummingbird with that amazing purple gorget! Also some nice squeaks and wing hums.
#birds #BirdBuddy cam

1 week ago 5172 572 99 19
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Cannon Beach, Oregon

1 week ago 4790 416 83 14
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Red-headed Trogon.

The Red-headed Trogon is a species of bird in the family Trogonidae.
A brightly-colored bird of dense evergreen forests, usually seen perched quietly on a mid-story perch.

📸: @rameshkarmakar_wildlife

1 week ago 440 38 5 1
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Video

We Ride at Dawn

1 week ago 10866 1480 208 117

This just in: The Pope is soft on crime! Also we hear he's into forgiveness and shit like that!

1 week ago 85 17 1 0

what a bunch of fuckin bullshit

1 week ago 84 11 8 0

“we don’t need access ramps to the shop, wheelchair users don’t come here“

why don’t the wheelchair users come to the shop, I wonder

1 week ago 65 10 0 0
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My flower painting 🌼

1 week ago 1960 127 55 5
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Good morning!
This tiny “snow fairy” is actually one of the most magical little birds on the planet - the long-tailed tit!

In winter, they puff up so much they look like floating snowballs with wings. Photography by @y.odamon

1 week ago 5146 497 9 22
Photo of host and guest
the following text:

Special Feature
The Science Behind Brain Fog
  In this episode, Haylie Pomroy speaks with Dr. Theoharis Theoharides about the scientific foundations of brain fog. Together, they clarify its definition, physiological mechanisms, and how it presents across various illnesses and cognitive disorders.

Dr. Theoharides further examines the relationship between brain fog and inflammation, explains how viral infections can contribute to the development of chronic illness, and discusses the role of microglia in neuroinflammation.

He also reviews supplements that may help inhibit microglial activation, explains alpha-gal syndrome, and outlines relevant laboratory testing that can assist individuals experiencing brain fog in gaining clearer insight into their current health status.

Photo of host and guest the following text: Special Feature The Science Behind Brain Fog In this episode, Haylie Pomroy speaks with Dr. Theoharis Theoharides about the scientific foundations of brain fog. Together, they clarify its definition, physiological mechanisms, and how it presents across various illnesses and cognitive disorders. Dr. Theoharides further examines the relationship between brain fog and inflammation, explains how viral infections can contribute to the development of chronic illness, and discusses the role of microglia in neuroinflammation. He also reviews supplements that may help inhibit microglial activation, explains alpha-gal syndrome, and outlines relevant laboratory testing that can assist individuals experiencing brain fog in gaining clearer insight into their current health status.

The Science Behind Brain Fog

www.youtube.com/watch?v=MSpE...

[Tom: I haven't watched this myself]

Image is from the AMMES April 2026 newsletter

#BrainFog

1 week ago 9 4 0 1
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Ruskin Spear (British, 1911-1990). Cat in a cardboard box (oil on board).

1 week ago 4446 584 53 20
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A painting of a stoat standing up and smiling as a snowflake lands on their nose. The background is changing seasons, with spring flowers and neon green grass at the bottom, shifting to summer grass, autumn grass and red leaves, and a snow topped mountain and branches at the top. There are little bugs investigating throughout (a monarch butterfly, a ladybug, and a bee.) The stoat is in the middle, and their fur color changes from brown to white to match the seasons.

A painting of a stoat standing up and smiling as a snowflake lands on their nose. The background is changing seasons, with spring flowers and neon green grass at the bottom, shifting to summer grass, autumn grass and red leaves, and a snow topped mountain and branches at the top. There are little bugs investigating throughout (a monarch butterfly, a ladybug, and a bee.) The stoat is in the middle, and their fur color changes from brown to white to match the seasons.

A stoat changing coats. ❄️🌷

1 week ago 2772 856 19 5
abstract expressionist study, gestural marks, fragmented forms, under a crescent moon, dark snow-capped Carpathians, a bright meteor splits the sky, colour field interaction, implied rather than literal, rhythmic composition --ar 5:7 --stylize 300 --v 7

abstract expressionist study, gestural marks, fragmented forms, under a crescent moon, dark snow-capped Carpathians, a bright meteor splits the sky, colour field interaction, implied rather than literal, rhythmic composition --ar 5:7 --stylize 300 --v 7

"Homecoming" #synthart #Artemis

1 week ago 2270 214 34 4
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Ice Out. Aurora & Milky Way In.

#landscapehotography
#nightphotography
#auroraborealis
#northernlights
#nightscapes
#minneosta
#fotosota
#bortle1

1 week ago 2001 206 13 4
4x4” acrylic painting of Orion splashing down with 3 red & white parachutes open against a blue sky with a couple clouds

4x4” acrylic painting of Orion splashing down with 3 red & white parachutes open against a blue sky with a couple clouds

you’ve moonscrolled your way to my art! I’ve been a full-time space artist since 2023 ✨

1 week ago 1096 100 9 0
Dunes with white sand under a cloudy blue sky. Various plants scattered on the dunes.

Dunes with white sand under a cloudy blue sky. Various plants scattered on the dunes.

Dunes at White Sands NM

#BlueskyMonday #ECK
#photography #landscape

1 week ago 1068 132 48 5
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Low tide sunset. 🌅

1 week ago 207 23 2 1
ME Action logo 
and the following text

ME Action: Join Us for #MillionsMissing 2026!  
In the U.S., new Medicaid rules will force people with ME and Long COVID to work 80 hours per month or lose their government health insurance, unless they can prove they have a "serious or complex medical condition” in order to get a "medically frail" exemption.  
​
We know that both are true for the majority of our community but, once again, we are having to fight to prove this to our health leaders. When ME is overlooked, people are denied the protections, services, and support that medically frail patients are supposed to receive. 
Read more here>>

ME Action logo and the following text ME Action: Join Us for #MillionsMissing 2026! In the U.S., new Medicaid rules will force people with ME and Long COVID to work 80 hours per month or lose their government health insurance, unless they can prove they have a "serious or complex medical condition” in order to get a "medically frail" exemption. ​ We know that both are true for the majority of our community but, once again, we are having to fight to prove this to our health leaders. When ME is overlooked, people are denied the protections, services, and support that medically frail patients are supposed to receive. Read more here>>

ME Action @meactnet.bsky.social : Join Us for #MillionsMissing 2026!

www.meaction.net/millionsmiss...

Also discusses there are plans for the UK for May

Image is from the AMMES April 2026 newsletter

#MEcfs #PwME

1 week ago 7 4 0 0