Weekly recap in ACR Journals banner - Arthritis & Rheumatology cover

New in Arthritis & Rheumatology #Medsky

CHI3L1 may contribute to systemic sclerosis endothelial-to-mesenchymal transition
doi.org/10.1002/art....

Dynamic changes in antibody titers predictive of systemic sclerosis disease progression
doi.org/10.1002/art....

↓

There's that and scientific literature has long shown cloud seeding to be inconclusive or minimally effective. I have found some people can't distinguish sales pitch from science in their "own" research

Synthesising genomes: Future promises, past metaphors - Making Science Public Yesterday morning I was packing for a holiday and briefly listened to the Today programme on Radio 4, just at the time that Pallab Ghosh was talking about a new initiative funded by the Wellcome Trust, namely a new Synthetic Human Genome (SynHG) project. I didn’t really have time to listen or read about it ...

This is a nice discussion by @bnerlich.bsky.social of the sci comms issues raised by the recent report of a "synthetic human genome project". There is something of a car crash going on between habitual ways of talking about biology and genomes and what...
blogs.nottingham.ac.uk/makingscienc...

Fascist cosplay.

ICE: The only government agency where a ski mask and no badge means “official business.”

"There has to be a way of letting the world realise this could be the beginning of the end. This is potentially the start of the decay of the oceans, which is going to be the start of the decay of mankind."
Powerful webstory 😱 about algae bloom thanks to Exxon's deceit and fossil-bribed politicians.

A fungi that can ‘eat you from the inside out’ could spread as the world heats up | CNN Infection-causing fungi responsible for millions of deaths a year will spread significantly to new regions as the planet heats up, new research predicts —and the world is not prepared.

A fungi that can ‘eat you from the inside out’ could spread as the world heats up

Not "could" but will spread in a non-linear fashion

My advice: keep your hands clean and do not enter with dirty fingers any opening in your body.

Clinics are hotspots of resistant fungi

How the humble chestnut traced the rise and fall of the Roman Empire The chestnut trees of Europe tell a hidden story charting the fortunes of ancient Rome and the legacy it left in the continent's forests.

Chestnut imperialism www.bbc.com/future/artic...

Thames Water boss ordered to tell MPs if executives received bonus payments Chris Weston, boss of Britain’s biggest water company, faces questions over ‘paused’ executive bonus scheme

Well done @amcarmichaelmp.bsky.social for challenging slippery Thames Water bosses for misspeaking (aka lying) about bonuses. Telling porkies to a Select Committee is serious. @weownit.org.uk @cathobbs.bsky.social @takebackwater.bsky.social www.theguardian.com/environment/...

Brain metastases Nature Reviews Disease Primers - An estimated 20% of all patients with cancer will develop brain metastases, with the majority of brain metastases occurring in those with lung and breast cancer and...

#Medsky🧪 #immunosky #oncosky #neurosky Up to 20 % of metastatic 🧠 tumors arise from primary BC www.nature.com/articles/s41... While primary #breastcancer is curable if caught early, metastatic tumors have significantly poorer survival rates. #Brainmetastases,

Article 1, Section 9 of the US Constitution: no person holding any office of profit or trust under them [The United States], shall, without the consent of the Congress, accept of any present, Emolument, Office or Title of any kind, whatever, from any King, Prince, or foreign State.

The New York Times describes Trump getting bribed with a plane as "raises substantial ethical issues" because they're too lazy to read the f****** Constitution.

Here it is:

🚨Earth's energy imbalance more than doubled in recent decades🚨

'if surprises lie ahead, for example, from unexpectedly large aerosol forcing (Hansen et al., 2023), or an unexpected loss of climate stability, then the imbalance is the first place this can be detected'
doi.org/10.1029/2024...

When my friends began to have babies and I came to comprehend the heroic labor it takes to keep one alive, the constant exhausting tending of a being who can do nothing and demands everything, I realized that my mother had done all these things for me before I remembered.

I need help: I‘m building an open data flood risk portal for #Denmark. I need around 500 Gb storage and need to host around 5 containers serving a couple of web services. As it is just a side project, what is the cheapest way to host it?

What would the energy companies hate?

If we didn't need them anymore.

🧵1/ Billionaires & corporations aren’t just sitting on piles of cash—they’re stockpiling #wealth so aggressively that it distorts the #economy. Think of it like monopoly, but real life: they’re buying up assets, driving prices up, and locking everyone else into renting forever. Without taxing them …

How little we’ve seen: A visual coverage estimate of the deep seafloor In decades of deep-sea exploration, humans have observed only 0.001% of the deep seafloor, leaving 66% of planet Earth unseen.

Fast-forward 4 years and a ton of research later, and my initial estimate remains the same--we've seen ~0.001% of the deep seafloor, an area approx the same as the size of Rhode Island.

@oceandiscleague.bsky.social published this work in @science.org Advances today: www.science.org/doi/10.1126/...

Just don’t forget:
“It is unnecessary for a prince to have all the good qualities I have enumerated, but it is very necessary to appear to have them .. to appear merciful, faithful, humane, religious.”
- Niccolò Machiavelli, The Prince, Ch. XVIII

"All capitalists want
capitalism for the masses
and socialism for the super
rich elites. That's kind of
the definition of capitalism
in my honest opinion."

- David Graeber

EPRI Webcast of Initial Findings from April 28, 2025 Iberia Blackout YouTube video by EPRI

If anyone wants to hear a bunch of power system experts talk about what we know about the Iberian blackout and what we don't, EPRI has you covered: www.youtube.com/watch?v=LNSt...

Early‐Warning Signals for Marine Anoxic Events Deoxygenation events in the eastern Mediterranean Sea show tipping point behavior at which the system abruptly shifted to an anoxic state Rise in variance and autocorrelation (“early-warning signal...

Transfer this paragraph to the whole Earth system:

"These statistical indicators (i.e, rise in autocorrelation and variance) are hallmarks of so-called critical slowing down, signaling a steady loss of resilience of the oxygenated state as the system approaches a tipping point"

Capisci?

#climate

England's water firms have paid out an astonishing £78,200,000,000 in dividends since privitisation - with 70% of investors currently being from overseas - Ian Overton in the @bylinetimes.bsky.social

Yet our bills go up? Why do we allow this con?!

Nationalise water now!

Intestinal mucosal immune responses induced by novel oral poliovirus vaccine type 2 and Sabin monovalent oral poliovirus vaccine type 2: an analysis of data from four clinical trials We found no evidence of differences in the intestinal mucosal immune responses induced by nOPV2 or Sabin mOPV2 and observed the strongest responses in infants.

This is good news.

Comparable immune responses (IgA & neutralising antibodies) with new oral polio vaccine compared to Sabin vaccine - hopefully can help interrupt circulating vaccine-derived poliovirus outbreaks.
@lancetmicrobe.bsky.social

#IDSky #ImmunoSky
www.thelancet.com/journals/lan...

"Labour.. say we just need to go further & faster. People think you're going in the wrong direction. They don't want you to go further & faster in taking away pensioners benefits or benefits from disabled people. They want you to stop & change direction"

Andrew Fisher is spot on!

Farmers in Iowa Are Caught in Trump’s Trade War (Gift Article) With high costs and low prices for their crops, soybean and corn farmers were already nervous as they planned for planting season this year. A big trade war isn’t helping.

Today’s serving of pablum on Iowa agriculture from the NYT has the distinction of being written by an Iowa farmer’s daughter.
It has many of the features you’d expect. Pick the medium size farm with the old tractors, only show the parts of the historical context making the farmers look sympathetic…

Techno-Optimism Won't Save the Day Your data is wonky

Let's get critical, critical 🕺

www.planetcritical.com/p/techno-opt...

Harnessing nature-based solutions to help combat flooding Natural England’s projects on the Wissey and Deben show how working with nature can combat flooding

What if wetlands could save our farms and our wildlife? A bold new approach by Natural England is taking root in Norfolk and Suffolk. Here's how it works ⤵️

@eastangliabylines.co.uk @naturalengland.bsky.social

Wanna see something cool?

At the Grammy's in 1976, Ella Fitzgerald and Mel Torme explained what jazz is.

The result? The crowd losing its mind. 🔥

May 4, 2007:

A nighttime supercell spawned 22 tornadoes in Kansas. Four were rated EF3+, and two were at least 1.5 miles wide. A devastating EF5 (the first rated using the EF scale) destroyed 95% of the town of Greensburg, killing 11 people and injuring 63.

Want safer city traffic? Welcome walkers and slow drivers down. Providence proved this 85 years ago.

In 1938-40, Rochester attempted to impose pedestrian control downtown. But Rochester's walking majority resisted control.