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Posts by Mrityunjay (Jay) Gupta

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Cryo-EM Study and In Vivo Chemical Mapping of the Methanosarcina acetivorans Ribosome and Its Dimerization via a Repurposed Enzyme and Translation Factor Despite the overall conservation of ribosomes across all domains of life, differences in their 3D architecture, rRNA sequences, ribosomal protein comp…

Excited to see a new #ribosome structure of a methanogen M. acetovorans from Anwesha in JBC @asbmbjournals.bsky.social to understand DMS reactivity of rRNA! Check it out here -

6 months ago 1 0 0 0
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VariantFoldRNA: a flexible, containerized, and scalable pipeline for genome-wide riboSNitch prediction Abstract. Single nucleotide polymorphisms (SNPs) can alter RNA structure by changing the proportions of existing conformations or leading to new conformati

Heartiest congratulations to Kobie @kobiek.bsky.social on a well-deserved Editor's Choice article in NAR Genomics and Bioinformatics! Check it out here -

10 months ago 4 0 0 0
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Identification and characterization of shifted GU wobble pairs resulting from alternative protonation of RNA RNA can serve as an enzyme, small molecule sensor, and vaccine, and it may have been a conduit for the origin of life. Despite these profound functions, RNA is thought to have quite limited molecular ...

Happy to share the first #preprint from the Bevilacqua lab of 2025! Led by Dr. Saon, we show the presence of a shifted GU wobble base pair in RNA crystal structures that requires charged or tautomeric nucleobases. #chemsky #ChemBio Check it out here - www.biorxiv.org/content/10.1...

1 year ago 4 1 0 0

Happy new year Brian and team! 🎉🎉🎉

1 year ago 1 0 1 0
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My modest attempt at making a scholar word cloud.. Try it out for yourself! scholargoggler.com

1 year ago 4 0 0 0
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Mrityunjay Gupta ‪Pennsylvania State University‬ - ‪‪Cited by 26‬‬ - ‪Ribozymes‬ - ‪RNA Modification‬ - ‪RNA structure‬

I'm finally here! Hi - I'm Jay, and I am currently a postdoc with Phil Bevilacqua Lab at Penn State. Interested in #RNA structure, #ribozymes #chemicalbiology ! Hope to find more fellow RNA people! Check out my scholar profile here - scholar.google.com/citations?us...

1 year ago 7 0 0 0