Tiny, 45 base long RNA can make copies of itself https://arstechni.ca #biochemistry #originoflife #evolution #ribozymes #Science #Biology #RNA

Computational De Novo Design of Group II Introns Yields Highly Active Ribozymes Group II Introns (G2Is) are large self-splicing ribozymes with promising biotechnological applications. This study utilized RNA inverse folding to design three novel G2Is. The designed intron Arq.I2,...

Have you ever wanted to design large and complex ribozymes from scratch? I know I have!

We used RNA inverse folding to design synthetic Group II Introns (G2Is) from the bottom up, resulting in highly active #ribozymes that splice in E. coli without proteins!

#intron #RNAsky #SynBio 🧬🧵(1/n)

How did #RNA and #ribozymes evolve during the #OriginOfLife 🌍? Nghe proposes a 3-stage scenario 🧬 #evolution
➡️ doi.org/10.1002/1873-3468.70065

right.
@moranlabchem.bsky.social
i've never understood the RNA world hypothesis. #ribozymes my ass! are there any examples of a ribozyme catalysing a METABOLIC reaction? or indeed anything besides messing with RNA/DNA? does rRNA even help catalyse peptide synthesis?

When you have the chance to attend a talk and a book signing by the Nobel Prize winner in your field, you do it 😊 #thecatalyst #rna #ribozymes
www.instagram.com/p/DH6qpNyy7K...

Mrityunjay Gupta ‪Pennsylvania State University‬ - ‪‪Cited by 26‬‬ - ‪Ribozymes‬ - ‪RNA Modification‬ - ‪RNA structure‬

I'm finally here! Hi - I'm Jay, and I am currently a postdoc with Phil Bevilacqua Lab at Penn State. Interested in #RNA structure, #ribozymes #chemicalbiology ! Hope to find more fellow RNA people! Check out my scholar profile here - scholar.google.com/citations?us...

David Horning @salkinstitute showing you can evolve RNA with RNA - such cool results! 🤯 #ribozymes #RNA23