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Posts by Saudat

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Evolutionärer Pfusch? Die enge Passform bei der menschlichen Geburt In dieser Podcast-Episode erklärt die Evolutionsbiologin Dr. Barbara Fischer die spannende Herausforderung der menschlichen Geburt: das Verhältnis von Kopfgröße Neugeborener zum mütterlichen Becken. O...

Barbara Fischer (KLI Group Leader for Evolutionary Biology) was interviewed for an episode of a podcast by Springer Medicine Vienna with the title “Evolutionärer Pfusch? Die enge Passform bei der menschlichen Geburt”

🎧 Listen (in German): springermedizin-hoergang.podigee.io/316-evolutio...

1 day ago 3 2 0 0
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💐 Congratulations to our Postdoctoral Fellow Marcelo Domingos de Santis on his new publication! 👏👏👏

"On 'Hennig’s Dilemma' and the Post-Systematics Wars"

www.kli.ac.at/en/the_kli/n...

5 days ago 9 3 0 0
Species-specific oxygen sensing governs the initiation of vertebrate limb regeneration Why mammals cannot regenerate limbs like amphibians do presents a long-standing puzzle in biology. To uncover the underlying differences, we compared amputation responses of embryonic mouse (Mus musculus) and Xenopus laevis tadpole limbs. Lowering ...

🚨 Why can’t mammals regenerate limbs like frog tadpoles or salamanders?
In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸
🔗 www.science.org/doi/10.1126/... #EvoDevo

1 week ago 262 111 21 10

Wrote a news article about our recent study on thermal limits🌡️

3 weeks ago 11 6 0 0

Excited to share my first preprint from my PhD w/ @justinmcrocker.bsky.social. We show that cell type-specific regulatory dominance promotes robustness and evolutionary innovation through interallelic transcriptional hubs, potentially expanding the mutational paths available to diploids. (1/18)

1 month ago 42 22 1 3

What if our assumption that regulatory networks are highly conserved is wrong? And every accession, individual, subspecies, etc does things very differently using the same tools?

1 month ago 10 3 2 0

Take from it what you want, but it's remarkable that the Greens in Baden-Württemberg, who just won the federal state elections, are considered, at the same time,

1. the most conservative Greens in the country
2. the most consequential on environmental policies
3. the most successful on the ballot

1 month ago 8 3 2 0

The Stochastic Pacemaker: Cumulative Behavioral Noise Drives Morphological Plasticity in Pea Aphids www.biorxiv.org/content/10.64898/2026.03...

1 month ago 0 1 0 0
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Gene regulatory networks: from correlative models to causal explanations Nature Reviews Genetics - In this Perspective, Maizels and Briscoe discuss the limitations of current models of gene regulatory networks and outline solutions to harness data abundance without...

New Perspective form Rory Maizels & me: "Gene regulatory networks: from correlative models to causal explanations"

Gene regulatory networks are supposed to give us mechanistic explanations of development, so why are we drowning in 'hairballs' of statistical correlations?

rdcu.be/e7zx7

1 month ago 122 46 2 2
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Society for the Study of Evolution Site description

Applications now open for the Graduate Research Excellence Grants! These provide evolutionary biology research funds for early and advanced Master’s and PhD students. Proposals due May 18.
www.evolutionsociety.org/content/soci...

1 month ago 22 26 0 0
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🌟📣We are happy to announce another new publication on the obstetrical dilemma, co-authored by Barbara Fischer and Philipp Mitteroecker:

"Over the edge: Empirical evidence for the cliff-edge model of obstetric selection"

www.kli.ac.at/en/the_kli/n...

Congratulations to the authors! 👏👏👏

2 months ago 4 1 0 0
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Inference and Visualization of Complex Genotype–Phenotype Maps Abstract. Understanding how biological sequences give rise to observable traits, that is, how genotype maps to phenotype, is a central goal in biology. Yet

Martí-Gómez et al. developed gpmap-tools, integrating models for inference, phenotypic imputation, and error estimation from multiplex assays of variant effect data or natural sequences in the presence of genetic interactions.

🔗 doi.org/10.1093/molbev/msag023

#evobio #molbio #compbio

2 months ago 3 2 1 0
Postdoctoral position in “Genomic signatures of adaptive evolution along the fast-slow life history continuum” (m/f/d) 80-100% The Department of Systems Analysis, Integrated Assessment and Modelling (SIAM) has an opening for a

Postdoc @eawag.bsky.social apply.refline.ch/673277/1341/...

2 months ago 3 6 0 0
Krasileva Lab – Research Lab

📣 Our lab is seeking a postdoc to study mutation mechanisms in fungi using cutting-edge sequencing + computational biology. No active posting/grant right now, but we’re excited to host postdoc fellowship applicants in our comparative immunology team.
Interested? Reach out DM email. krasilevalab.org

2 months ago 18 16 0 0
Fig. 4. of Kraus 2026. Normal mammalian cardiogenesis and ambiogenic events hypothesized to be required for proper outflow tract development during placentation, along with associated developmental and phylogenetic phenotypes.

Fig. 4. of Kraus 2026. Normal mammalian cardiogenesis and ambiogenic events hypothesized to be required for proper outflow tract development during placentation, along with associated developmental and phylogenetic phenotypes.

💐 Congratulations to our 2025 KLI fellow, Nina Kraus @ninakraus.bsky.social, on her new publication in the Journal of Experimental Biology on
"Environmentally dependent developmental induction as a potential driver of heart evolution"!
👏👏👏

📃 doi.org/10.1242/jeb....

2 months ago 7 4 0 0
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Chill-tolerant Drosophila species maintain electrogenic muscle membrane potential to resist cold-induced depolarization Summary: Unlike chill-sensitive Drosophila that lose muscle membrane polarization in the cold, chill-tolerant species can maintain polarization via preservation of Na+/K+-ATPase-driven electrogenesis,...

Why are some Drosophila flies paralyzed at cold temperatures, and others aren't? 👇

2 months ago 4 3 0 0
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A detailed characterization of the #Drosophila yolk-GAL4 transgene used for expression in the fat body shows that the Gal4 induces physiological defects in adult females.

Learn more in #GENETICS about new alternative fly lines that mitigate this effect: buff.ly/SxA6L1E

2 months ago 3 3 0 0
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Seminars

Tanja Schwander is closing the #PopGen Seminar winter term by speaking tomorrow on "Origins and consequences of unorthodox reproductive modes: Insights from stick insects". Our #PhD students look forward! Full schedule and streaming details at popgen-vienna.at/news/seminars/ #evolution

2 months ago 3 2 0 0
Continent-wide differentiation of fitness traits and patterns of climate adaptation among European populations of Drosophila melanogaster #Drosophila PubMed link

Continent-wide differentiation of fitness traits and patterns of climate adaptation among European populations of Drosophila melanogaster
#Drosophila

7 months ago 1 2 0 0

Morphomechanics and Developmental Constraints in the Evolution of Ammonites Shell Form https://pubmed.ncbi.nlm.nih.gov/27921363/ #EvoDevo

3 months ago 1 2 0 0
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Join our KLI Colloquium:
"On Experimental Models of Developmental Plasticity and Evolutionary Novelty"
Speaker: Patricia BELDADE (Lisbon University)
🕒 15 Jan 2026, 3:00 PM CET
🗺️ at KLI, join online via ZOOM (link & info: www.kli.ac.at/en/the_kli/n...)

3 months ago 11 5 0 1
Text: Society for the Study of Evolution, American Society of Naturalists, Society of Systematic Biologists, Undergraduate Community at Evolution Program. Applications due January 20, 2026.

Text: Society for the Study of Evolution, American Society of Naturalists, Society of Systematic Biologists, Undergraduate Community at Evolution Program. Applications due January 20, 2026.

Are you an undergrad interested in ecology, evolution or related fields? Apply by January 20 for our Undergraduate Community at Evolution program! This program provides funding, mentoring, and a presentation opportunity at #Evol2026. www.evolutionsociety.org/content/educ...

3 months ago 13 19 1 0
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Why does life explore so few of the forms it could possibly take? Using fractal descriptors, this #scienceadvances paper shows that Earth’s biosphere clusters around simple shapes, reflecting deep evolutionary constraints. @artemyte.bsky.social @manlius.bsky.social www.science.org/doi/pdf/10.1...

3 months ago 229 76 5 6
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Multivariate trait evolution: models for the evolution of the quantitative genetic G-matrix on phylogenies Abstract. Genetic covariance matrices (G-matrices) are a key focus for research and predictions from quantitative genetic evolutionary models of multiple t

How do genetic variances and covariances evolve over deep time? This paper unifies quantitative genetics and macroevolution with analytical models for G-matrix evolution on phylogenies, enabling new tests of multivariate trait evolution.
academic.oup.com/evlett/artic...

4 months ago 25 9 1 0
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Generative epigenetic landscapes map the topology and topography of cell fates | PNAS Epigenetic landscapes were proposed by Waddington as the central concept to describe cell fate dynamics in a locally low-dimensional space. In mode...

Very happy to share our 'Evoscape' paper, now published in PNAS ! www.pnas.org/doi/10.1073/...

4 months ago 78 27 1 0

Hooray! It's finally out

4 months ago 11 3 0 0

Istanbul people, an Astronomer needs your help!

4 months ago 1 1 0 0
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RegEvol: detection of directional selection in regulatory sequences through phenotypic predictions and phenotype-to-fitness functions Regulatory DNA controls when and where genes are expressed, making it a key driver of phenotypic evolution. Yet detecting selection in non-coding regions remains difficult, as most approaches rely on ...

I'm excited to present this new model to detect positive selection on regulatory sequences, which has been 3 years in the making!
Thanks to Alexandre Laverré and @phylogenetrips.bsky.social for their amazing work on this project. 😃
doi.org/10.1101/2025...
Thread!

4 months ago 22 6 1 2

Excited to share that I’m starting a research group at MPI for Biology Tübingen — and we’re recruiting PhD students!

We are offering two fully funded PhD positions on sex determination and development in Hymenoptera 🐜🐝.

Please share with prospective students who might be interested.

4 months ago 11 9 1 0
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***Super cool-project alert***⚠️ Come work with @dirkmetzler.bsky.social and me in trying to understand how transcriptional noise evolves in a phylogenetic context 🧬 Deadline 15th Dec 2025 (Project funded by @dfg.de @gevol.bsky.social)

4 months ago 16 19 0 0