In this week's glossary carousel we explain:
• Dysplasia
• Lesion
• Pancreatic intraepithelial neoplasia (PanIN)

Understanding these early biological changes helps researchers identify opportunities for earlier detection and prevention.
#PancreaticCancer #CancerResearch #EarlyDetection

🚨 500,000 #pancreaticcancer deaths in 2020. The biggest challenge: We can’t diagnose it in time. #WorldCancerDay reminds us that every diagnosis remains a race against time
And we’re committed to develop a biomarker panel that can reliably detect PDAC at its earliest stages
#UnitedByUnique #WCD2026

Excited that Prof. Klaus Pantel was speaker at the Inaugural EUnetCCC Educational Seminar in Barcelona yesterday, contributing "Liquid Biopsy: From Discovery to Clinical Implementation"

#EUnetCCC #LiquidBiopsy #pancreaticcancer #precisiononcology #EUfunded

Today is #WorldPancreaticCancerDay 💜
#Pancreaticcancer is projected to become the second leading cause of cancer-related deaths in Western societies by 2030. A stark reminder of why our work matters.
Today, our thoughts are with all patients and families affected by this devastating disease. 💜
#WPCD

Approaches to early cancer diagnosis and the impact of artificial intelligence in oncology | Webinar YouTube video by PANCAID

How is #AI transforming early cancer detection?
Experts from @phireproject.bsky.social, PANCAIM and PANCAID explore how data, innovation & collaboration drive precision oncology.
🎙 Moderated by Federica Zanca (EIC)
📺 Watch now: www.youtube.com/watch?v=aUhZ...

#CancerResearch #AIinOncology

Congrats Steffi!

Honored to share some big news: I’m now tenured as a W3 Professor of Organic Chemistry @UniCologne! Immensely grateful to all the group members who contributed to this journey🙏 — this milestone is ours to share. @ChemUniCologne #OrganicChemistry #Tenure 🍾🎉🧪🧬

🚨 New PANCAID Masterclass!
How is #AI transforming pancreatic cancer research?
Dr Núria Malats & Sergio Sabroso (CNIO) explain its role in early detection and #precisiononcology.

▶️ https://youtu.be/H-_Xv3H7fZI
@nuriamalats.bsky.social @cniostopcancer.bsky.social 

#CancerResearch #PancreaticCancer

PHIRE, PANCAID, PANCAIM Approaches to early cancer diagnosis and the impact of artificial intelligence in oncology Register for our webinar 15 October 2025 14:00 - 15:00 CEST Registration link: https://events.teams.microsoft.com/event/1fba7a3a-b605-4bcd-9b99-2076044436a7@ea8b78d9-ccc1-45ec-94de-369c8af49a53 More information: https://pancaid-project.eu/news-events/events/ Funded by the European Union

Join our webinar “Approaches to Early Cancer Diagnosis and the Impact of Artificial Intelligence in Oncology”!
@phireproject.bsky.social, #PANCAIM & @pancaid.bsky.social are proud to discuss how AI is transforming #oncology.

🔗 Register: events.teams.microsoft.com/event/1fba7a...

#CancerResearch

New #award for #EarlyCareerResearchers!

You can now apply for our Meeting Award, which will support participation in the conference #Biochemistry 2026 (March 16-18, 2026) with 500 € and give you a one-year, free membership in our Division!

en.gdch.de/network-s...

#ChemSky #ChemBio #ECR @gdch.de

Genomic and chemical characterization of cytotoxic Ahp-cyclodepsipeptides from Phormidium using Thamnocephalus platyurus bioassay Toxic benthic cyanobacterial mats have been identified globally as a potential health hazard since they can produce potent cyanotoxins. Such mats have…

Thrilled to see our study on novel toxins from cyanobacteria blooms in #Fribourg in STOTEN! Our results indicate that Phormidium is the producer of cyanopeptolins, whose side chains are crucial for their activity.

Great collaboration with Pilar Junier

www.sciencedirect.com/science/arti...

🔦 PANCAID Partner Spotlight: @uu.se
The labs of @masoodkamali.bsky.social & @globischlab.bsky.social bring cutting-edge EV, proteomics & metabolomics expertise to PANCAID.
🟣 Working together on biomarker discovery in WP2.

@scilifelab.se
#Metabolomics #CancerResearch

Thanks for highlighting our recent fecal metabolite study.

The Mass Spectrometry Query Language (MassQL) is an open-source language for instrument-independent searching across mass spectrometry data for complex patterns of interest via concise and expressive queries without the need for programming skills.

www.nature.com/articles/s41...

The study was published in the United European Gastroenterology (UEG) Journal. Thanks to our other co-authors Fan Yang, Sara Nikolic and Miroslav Vujasinovic. The aim of our study is to identify fecal metabolites towards a non-invasive detection of pancreatic diseases. #metabolomics #biomarkers

Differences in the Fecal Metabolome of Autoimmune Pancreatitis Patients Background Chronic pancreatitis is a risk factor for pancreatic cancer. Autoimmune pancreatitis is a unique form of chronic pancreatitis that is primarily characterized by its immune mediate etiolog.....

Congrats to @vladyslavdovhalyuk.bsky.social for his first author publication detailing differences in the fecal metabolome of autoimmune and chronic pancreatitis. This study is another close collaboration with our medical experts from @maloehr.bsky.social lab. onlinelibrary.wiley.com/doi/10.1002/...

I am delighted to share our cover art with a creative design by our PhD student @ioannatsiara.bsky.social. Thank you #JAFC for selecting her art work on detailing the discovery of six phase II metabolites specific for a (poly)phenolic dietary intervention. #metabolomics pubs.acs.org/doi/10.1021/...

🎉 Calling all #Metabolomics students & ECRs!

We're offering a $500 AUD travel grant to support attendance at #Metabolomics2025 in Prague, Czechia!

🕛 Apply by April 20, 2025 (AEST)

👉 tinyurl.com/metabolomics...

#ANZMetSoc #TravelGrant #Student #ECR

Obituary - Per Jemth

This spring has not been as expected. While we still miss our amazing colleague Per Jemth we try to follow his advice to remember the good times and laugh a lot. www.sciencedirect.com/science/arti...

There are days in life that shake you.

I’m shattered 💔 to share that I just found out that the US Government terminated my 2024 NIH Director’s Early Independence Award (~$2 million), threatening my long-promised assistant professor job at Columbia University
& academic career... 1/🧵

Celebrate International Women's Day by reading the Special Issue of the Journal of Proteome Research, highlighting the essential contributions women scientists have made—and continue to make—in the fields of Proteomics and Metabolomics. ow.ly/eBcV50TWOpV #InternationalWomensDay 🧪

Characterizing the Sulfated and Glucuronidated (Poly)phenol Metabolome for Dietary Biomarker Discovery (Poly)phenols, bioactive compounds abundant in plant-based diets, have attracted interest for their potential role in preventing chronic diseases including cardiometabolic and neurodegenerative diseases. This study investigates the global sulfatome and glucuronidated metabolome in urine samples from 100 healthy adults collected pre- and postintervention following a 3-day (poly)phenol-rich intervention consisting of flaxseeds, raspberry powder, and soy milk. Using untargeted mass spectrometric metabolomics combined with selective phase II enzymatic treatment, we detected 156 sulfated and 143 glucuronidated metabolites in urine samples. Significant changes postintervention were observed for 91 sulfates and 94 glucuronides. Receiver operating characteristic curve analysis identified a combination of six polyphenol-derived key metabolites: glucuronidated daidzein and the sulfated compounds of pyrogallol, ferulic acid, 4-methoxyphenol, enterolactone, and resorcinol, which resulted in the best combination with the highest predictive AUC of 0.97. These findings underscore the utility of these metabolites as sensitive and selective biomarkers of (poly)phenol dietary intake.

Characterizing the Sulfated and Glucuronidated (Poly)phenol Metabolome for Dietary Biomarker Discovery #JAFC #MassSpec pubs.acs.org/doi/10.1021/...

Please contact us if you are interested in the investigation of sulfated and glucuronidated metabolites in biological samples and polyphenol interventions.

#metabolomics #chembio #microbiome #phaseIImodifications

Characterizing the Sulfated and Glucuronidated (Poly)phenol Metabolome for Dietary Biomarker Discovery (Poly)phenols, bioactive compounds abundant in plant-based diets, have attracted interest for their potential role in preventing chronic diseases including cardiometabolic and neurodegenerative diseas...

Check out our new publication on the investigation of phase II modifications as dietary markers. Big congrats for the dedicated work by our PhD student @ioannatsiara.bsky.social & our former Master's student Belén Hervás Povo in collaboration with Ana Rodriguez-Mateos. pubs.acs.org/doi/10.1021/...

Beyond excited to announce our in-person symposium to celebrate the 25th anniversary of ChemBioChem/ChemPhysChem!

Advances in Structural Analysis of Biomolecules
From Subcellular Imaging to Drug Design

October 23-24, 2025, Berlin

Please like and share: cbc-cpc2025.org

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

‼️PhD Position in Chemical Biology at the University Antwerp‼️#chembio

✔️Deadline: ‼️February 20, 2025‼️
✔️Find full details and submit your application here: www.uantwerpen.be/en/jobs/vaca...

Thank you @stephanhacker2.bsky.social for highlighting me talk at the fantastic #advancesChemBio conference. Great interactions with an exciting schedule in Frankfurt. #ChemBio #microbiome #metabolomics

Amazing talk by @globischlab.bsky.social at #AdvancesChemBio. He talked about studying the changes of metabolites produced by the microbiome in different diseases. Exciting chemical biology tools to enrich metabolites with various functional groups. (1/2) onlinelibrary.wiley.com/doi/10.1002/...

A great meeting on "Advances in Structural Analysis of Biomolecules" celebrating 25 years of ChemBioChem and ChemPhysChem will be happening on October 23rd and 24th in Berlin, Germany.
If you want to participate, you can already register and send in an abstract.
#chemsky #ChemBio
www.cbc-cpc2025.org