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Posts by Institut Imagine

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We are thrilled to host Dr. Isidro Cortés-Ciriano (@ebi.embl.org/ @sangerinstitute.bsky.social) for our weekly Monday Seminar.
He's sharing important insights on multimodal cfDNA profiling and novel single-molecule sequencing approaches for minimally invasive liquid biopsies in paediatric tumours. 🧬

1 day ago 5 2 0 0
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Happening now at @institutimagine! 🔬 Prof. Elisa Oricchio (Swiss Institute for Experimental Cancer Research) is taking the stage for our Monday Seminar.

She's diving into how integrating linear & 3D genomic analyses helps us understand tumor evolution & design new therapies. 🧬

#Cancer #Genomics

1 week ago 9 2 0 0
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🧫 Wrapping up today's fantastic MAGIC seminar is @manusingh.bsky.social (@inem-necker.bsky.social). His talk: "Single-Cell Mapping of the Reawakening of Ancient Foes in Ageing Disorders." A deep dive into the molecular & cellular mechanisms of Alzheimer. Thanks to all speakers & see you next week! 🧪

1 week ago 4 3 0 0
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🔒 How do we advance research while protecting patients? Simon Lévesque (@usherbrooke.bsky.social – Québec & @upcite.bsky.social) is taking the MAGIC stage to tackle "Federated Learning and Data Privacy." Crucial concepts for collaborative science and privacy-protection! 🧵

1 week ago 4 1 1 0
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📊 Next up at MAGIC: Antonio Rausell from right here at #InstitutImagine. He is discussing his latest work: "Predicting digenic interactions in rare diseases using graph neural networks." A powerful AI approach to complex genetics. 🧵

1 week ago 4 1 1 0
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🧬 We are LIVE at the weekly MAGIC seminar at Imagine! Kicking us off is @joshwaterfall.bsky.social (@institutcurie.bsky.social ) presenting "Improved Out of Distribution Embeddings with AutoEncoders." Fascinating insights into computational biology! 🧵

1 week ago 6 3 1 0
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Familial lupus associated with a P2RY8 variant: navigating the boundary between monogenic disease and genetic susceptibility to #lupus. New report from Clémence David, Marie-Louise Frémond @institutimagine.bsky.social and colleagues: rupress.org/jhi/article/...

@esidsociety.bsky.social

2 weeks ago 6 5 0 0
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Cancer : Paul Bastard, 25 millions de dollars pour renverser le combat contre les tumeurs Le chercheur de l'Institut Imagine tente de comprendre pourquoi certaines personnes à risque ne développent jamais de cancer. Un projet à front reversé, auréolé début mars d’un Cancer Grand Challenge,...

Le secret pour vaincre le cancer se cache peut-être chez ces fumeurs, buveurs et autres resquilleurs, une vie passée à coucher avec le mal sans jamais se faire prendre.Quest-ce qui les protègent ? Projet immensément prometteur @institutimagine.bsky.social @lexpress.fr
www.lexpress.fr/sciences-san...

3 weeks ago 4 3 0 0
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David, Frémond @institutimagine.bsky.social et al. identify a heterozygous P2RY8 E323G substitution in a father and son with cutaneous #lupus and enhanced type I #interferon signaling supports a role for P2RY8 in lupus causation rupress.org/jhi/article/...

3 weeks ago 5 2 0 0
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How do “super-avoiders” manage to stay cancer-free?

Set up to investigate this is Paul Bastard and team ATLAS – one of five newly funded teams awarded $25m (£20m) through Cancer Grand Challenges.

Watch the takeover episode (on YouTube): youtu.be/hAjvmBReo-8

3 weeks ago 4 1 0 0
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🏆 Le Pr Polak a reçu le prix Gilberte et Jacques Tacussel, récompensant le travail clinique et de recherche à long terme mené par toute son équipe sur le diabète du très jeune enfant, menant à découvrir les propriétés neuro-protectrices de molécules insulino-sécrétrices.

3 weeks ago 3 2 0 0
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EU-IFNp: a European study to decode the Natural History of Type I Interferonopathies | Institut Imagine

Institut Imagine is proud to lead a clinical research project named “EU-IFNp”, coordinated by Professor Marie-Louise Frémond. This is a multicentric European study dedicated to children and adults with genetic type I interferonopathies (IFNp-I) : www.institutimagine.org/en/eu-ifnp-e...

4 weeks ago 3 2 0 0
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🔴 Happening NOW at Institut Imagine! Dr. Mira Kassouf (WIMM, @ox.ac.uk) is presenting our Monday Seminar: "The role of facilitators in super-enhancers and gene regulation." 🧬 She is presenting her fascinating research on the intricacies of gene control! #Genetics #InstitutImagine

4 weeks ago 5 2 0 0
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Le Colloque « Génétique et Société » a réuni hier à l’Institut Imagine scientifiques, médecins, philosophes et représentants de la société civile, en partenariat avec le CCNE et l’Agence de la Biomédecine.

1 month ago 3 1 0 0
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🔚 Clôture du colloque ! Pr Bana Jabri, Dr Marine Jeantet et Pr J.-F. Delfraissy partagent leurs ultimes réflexions sur l'évolution de la bioéthique en France. Merci de nous avoir suivis ! 👋

1 month ago 3 3 0 0
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✨ "Entre puissance, sagesse et compassion : quel avenir pour le vivant ?" Matthieu Ricard, généticien de formation et moine bouddhiste, nous offre cet après-midi un regard croisé inspirant sur notre rapport au progrès. 🌱

1 month ago 3 2 1 0
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🎙️ Pr J.-F. Delfraissy (CCNE) ouvre les débats : "Bioéthique, États Généraux, un enjeu de démocratie". Il rappelle une idée forte : refuser d'assumer le progrès, c'est risquer de renoncer à notre capacité d'agir. ⚖️

1 month ago 3 2 1 0
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🔴 C'est parti pour le colloque "Génétique et Société" (42e Séminaire P. Royer) ! Ouverture de cette riche journée par le Pr Bana Jabri (Inst. Imagine) et le Dr Marine Jeantet (Agence de la Biomédecine). Suivez notre live ! 🧬

1 month ago 4 3 1 0
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👏 Congratulations to Maria Alejandra Lizarralde-Iragorri on being awarded the highly prestigious Marie Skłodowska-Curie Postdoctoral Fellowship!

Maria will be carrying out her research in Hermine Laboratory, under the co-supervision of Sara El Hoss and Thiago Trovati Maciel.

1 month ago 4 1 0 0
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The STING HAQ haplotype and clinical non-penetrance in COPA syndrome. New report from Clémence David, Marie-Louise Frémond @mlfremond.bsky.social @institutimagine.bsky.social @upcite.bsky.social and colleagues: rupress.org/jem/article/...

#HumanDiseaseGenetics #InnateImmunity #inflammation

1 month ago 4 3 0 0
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Cerebral amebiasis due to #Acanthomoeba sp. in a patient with complete gp91phox deficiency. New report from Marie Roelens, Jacinta Bustamante and colleagues @hopitalnecker.bsky.social @institutimagine.bsky.social: rupress.org/jhi/article/...

@esidsociety.bsky.social

1 month ago 3 3 0 0

Welcome aboard! We're incredibly happy to have you as part of Imagine! 🎉

1 month ago 1 0 0 0

I am very happy to share that I've started my new position @upcite.bsky.social and opened my lab @institutimagine.bsky.social 🎉

In the lab we will study how differences in X-linked gene dosage between the sexes affect fetal growth and survival and contribute to sex differences later in life 👩‍🔬🧪🧬🧫

1 month ago 49 11 13 0
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🎙️ Live from Institut Imagine's Monday Seminar!

Dr. Edor Kabashi is currently presenting "From Charcot to ALS: Defining therapeutic avenues." Fascinating deep dive into the next steps for ALS treatments. 🧬✨

#InstitutImagine #ALSResearch #Charcot

1 month ago 5 3 0 0
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Autoantibodies neutralizing type I IFNs in 40% of patients with WNV encephalitis in seven new cohorts In 13 cohorts of individuals with WNV infection, the risk of WNV encephalitis is increased 20 to >>2,000 times by circulating auto-Abs neutralizing t

1/ Which human infectious disease is best understood in 2026? West Nile virus encephalitis, with 40% of cases attributed causally and mechanistically to auto-Abs neutralizing type I IFNs. doi.org/10.70962/jhi...

1 month ago 6 4 1 0
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STING haplotype alone does not fully account for disease expression in COPA syndrome @jem.org
rupress.org/jem/article-... @institutimagine.bsky.social

1 month ago 2 1 0 0
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What makes brain development unique across different species?
We’re diving into that exact question at our weekly Monday Seminar!

Prof. Denis Jabaudon (University of Geneva & Institut Imagine) is presenting his work: "Developmental gene expression driving species-specific cortical development." 🧠

1 month ago 6 1 0 0
Journée internationale des droits des femmes 2026 à l'Institut Imagine
Journée internationale des droits des femmes 2026 à l'Institut Imagine YouTube video by Institut Imagine

👩🏻‍🔬 À l’occasion de la Journée internationale des droits des femmes, l’Institut Imagine donne la parole à celles qui font avancer la recherche.

Voir la vidéo : www.youtube.com/watch?v=2v_W...

1 month ago 4 1 0 0
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DREPAMIR est lancé ! Cet essai de thérapie génique pour la #drépanocytose, la plus fréquente des maladies du sang en France, est porté en collaboration par @institutimagine.bsky.social, @ap-hp.bsky.social et @afm-telethon.bsky.social

ℹ️ 7M de personnes sont atteintes dans le monde

👉 afm-telethon.fr

1 month ago 6 4 0 0
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L'équipe internationale ATLAS, coordonnée par le Dr Paul Bastard de l'Institut Imagine, vient de décrocher un financement exceptionnel : jusqu'à 25 millions de dollars sur près de 5 ans, attribué par le prestigieux programme Cancer Grand Challenges !

1 month ago 4 4 0 0