Super excited to share this preprint! How do we disentangle underlying structure from the particular features of a learning episode to benefit future learning? We find that memory reactivation during sleep promotes this structure abstraction process.

www.biorxiv.org/content/10.6...

Delighted to share our discoveries about one of the brain's neurotransmitter systems:
www.biorxiv.org/content/10.6...

Together with colleagues at the @alleninstitute.org, we have learned a lot about a tiny cluster of neurons in the brainstem locus coeruleus (LC) that releases norepinephrine (NE). 1

www.science.org/doi/10.1126/...

"mental imagery reactivates the same sensory codes used during visual stimuli, suggesting the existence of a generative model capable of synthesizing detailed sensory contents from an abstract, semantic representation."

We're excited to share our new study on decoding brain activity in participants with post-stroke aphasia! We think this is an important step towards cognitive brain-computer interfaces for patients with language disorders

www.biorxiv.org/content/10.6...

1/8

And here’s the eclipse photo from Artemis II. I am in tears.

A crescent Earth seen setting behind a vast lunar landscape of craters.

NASA's first image from the Artemis II close flyby of the moon shows "Earthset," with a crescent Earth seen over the moon's cratered surface.

That's home. That's us.

This image of home just came down from the Artemis II crew.

Taken after their translunar injection burn, there are aurorae at top right and lower left, and zodiacal light at lower right.

Credit: NASA/Reid Wiseman

Thrilled and grateful to share our paper out today in
@nature.com (rdcu.be/fbd7J). We used a brain machine interface (brain computer interface, #BCI) to causally test the origin of the high-gamma band of local field potentials #LFP.
Results impact how we interpret many studies of #brain function

Science peeps! Excited to share first of two preprints just uploaded. This one concerns a person who hears sounds when she moves her eyes! We could actually record these sounds and verify they were connected to eye movements 1/
www.biorxiv.org/content/10.6...

Computational framework to predict and shape human–machine interactions in closed-loop, co-adaptive neural interfaces - Nature Machine Intelligence Madduri et al. introduce a computational framework grounded in control and game theory to model co-adaptation between users and decoders in neural interfaces. This framework enables a principled desig...

If you're interested in emerging ideas in neural interfaces, I humbly suggest my lab's latest: www.nature.com/articles/s42...

Neural interfaces create dynamic interactions between the brain & devices. This means mean we need new engineering approaches beyond typical ML to "decode" a static brain

More new results, this time from the amazing Lily Kramer! 🎉
“Sequential experience reshapes population representations in visual cortex” doi.org/10.64898/202...
Visual experience unfolds in time. We asked how temporal structure reshapes population activity in visual cortex.
🧪🧵1/

New preprint: our lab’s first Alzheimer’s paper! “Loss of neuronal population organization links pathology to behavior in a model of Alzheimer's disease”
www.biorxiv.org/content/10.6... 🧪🧵1/

🧠What if increasing neuronal firing could actually reduce fMRI connectivity?
📡What drives long-range fMRI connectivity?

I’m very excited to share that my PhD work is now out as a preprint
Check this out! 👇
doi.org/10.64898/202...

This brain–computer interface decodes attempted finger movements from cortical activity and translates them into keystrokes at 22 words per minute, potentially transforming communication for individuals with ALS or spinal cord injury! 🧪

www.nature.com/articles/s41...

A complete set of canonical nucleobases in the carbonaceous asteroid (162173) Ryugu - Nature Astronomy Samples returned from the asteroid Ryugu contain all five canonical nucleobases (A, G, C, T and U). Their presence in Ryugu and Bennu supports the hypothesis that carbonaceous asteroids contributed to the prebiotic chemical inventory of early Earth.

Samples returned from the asteroid Ryugu contain all five canonical nucleobases (A, G, C, T, U). Their presence in Ryugu and Bennu supports the hypothesis that carbonaceous asteroids contributed to the prebiotic chemical inventory of early Earth. http://dlvr.it/TRWtVp ☄️

Can electrical microstimulation be used to steer cortical population activity on- and off-manifold? Our new preprint says yes — using data-driven control in macaque PFC. Joint work with @gbarzon.bsky.social, Anandita De, Isaac Moran, Conner Carnahan, and Luca Mazzucato.

Thinking out loud: How inner speech can transform brain-computer interfaces What if the voice in our heads had the potential to revolutionize communication for people with paralysis or progressive disease that affected their ability to speak? Recent research shows that inn…

Can the voice in our heads revolutionize communication for people who can't speak?

Learn how inner speech is decoded from brain activity and the concerns it raises about protecting our private thoughts: pennneuroknow.com/2026/02/17/t... (by @kara-mcgaughey.bsky.social)

#PsychSciSky #SciComm 🧠🟦 🧪

Neuroscience has a species problem If neuroscience is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle.

The biggest problem holding neuroscience back right now isn’t data or tools, thanks in large part to the BRAIN Initiative.

It’s fragmentation across species. I wrote this to hopefully spark discussion around an issue that can only be solved as a community👇

www.thetransmitter.org/animal-model...

The basal ganglia output is often framed as a motor gate: corticostriatal circuits select an action, then GPi/SNr-thalamus helps release it. In humans, we find this same pathway carries cognitive variables embedded in movement signals—and even produces learning-relevant signals after feedback. 1/10

Writing a book worth reading *should* take time. It should take effort. The crafting of it and the thinking in it go hand in hand. And the rewards, for both the author and the readers, come from that effort. That the AI bros don't understand this is disturbing and revealing.

Building compositional tasks with shared neural subspaces Nature - The brain can flexibly perform multiple tasks by compositionally combining task-relevant neural representations.

Thrilled that my paper is out in the @nature.com. We explored how the brain builds complex tasks by compositionally combining simpler sub-task representations. The brain flexibly performs multiple tasks by dynamically reusing neural subspaces for sensory inputs and motor actions

rdcu.be/eRVUk

More than meets the eye: How different animals see the world What would it be like to see through the eyes of another animal? Learn how different animals see the world.

Ever wondered what it would be like to see through the eyes of another animal?

Explore the fascinating diversity of eye designs across the animal kingdom in this week's post by @catrinahacker.bsky.social: pennneuroknow.com/2026/02/10/m...

#PsychSciSky #SciComm 🧠🟦 🧪

Oregon primate center to negotiate transition to sanctuary The board of directors at Oregon Health & Science University, which runs the primate center, voted unanimously for the move.

BREAKING: The Oregon Health & Science University board of directors has voted to begin negotiations with the NIH about potentially transitioning the university’s primate research center to a sanctuary for the animals.

By @callimcflurry.bsky.social

#neuroskyence

bit.ly/4a6mycK

Our paper is out in @natneuro.nature.com!

www.nature.com/articles/s41...

We develop a geometric theory of how neural populations support generalization across many tasks.

@zuckermanbrain.bsky.social
@flatironinstitute.org
@kempnerinstitute.bsky.social

1/14

2026 is proving to be a wonderful year for first time fungi finds so far. Looks like this is the rarely recorded Henningsomyces candidus - tiny little macaroni-like tubes found on a very rotten piece of wood in Southeast England. #fungifriends #fungi #mycology #naturephotography

Sensory adaptation supports flexible evidence accumulation during perceptual decision making www.biorxiv.org/content/10.64898/2026.02...

Imagine wearing a #jellyfish as a helmet!?!
Well, that’s exactly what this juvenile jack is doing! Mostly immune to its sting, the jack has taken the jellyfish prisoner.

Shot using #scuba, out over the deep abyss, drifting at night.
#blackwater #blackwaterdiving #scubadiving #gug

When insects lose their minds: The fascinating world of parasitic fungi You might think mind control is the stuff of science fiction, but for many fungi it’s just what they do. Explore how parasitic fungi control the insects they infect.

You might think mind control is science fiction, but for some fungi it’s just what they do.

Explore the fascinating world of parasitic fungi and how they control infected insects in this week's post by @catrinahacker.bsky.social: pennneuroknow.com/2026/01/27/w...

#PsychSciSky #SciComm 🧠🟦 🧪

Our new paper (with @biotay.bsky.social) is out and on the cover story of @currentbiology.bsky.social !!!! Veronika, a Carinthian mountain cow flexibly uses a “multi-purpose tool” to scratch herself. A video and more information will follow in the comments.
www.cell.com/current-biol...