New paper in Genes & Dev: we dissected how Sox2 — a key pluripotency TF — is regulated by a distal enhancer cluster (SCR) 100 kb away. The results challenge simple models of cohesin-mediated loop extrusion of gene regulation. genesdev.cshlp.org/content/earl... 🧵
Germ cells have their own versions of core transcription factors and fertility depends on them.
We're hiring a PhD student to figure out how! 📢
Fly genetics + proteomics + genomics. Fully funded.
Aarhus University 🇩🇰
Deadline May 1 👇
Please share with anyone who might be interested!
I could not agree more!
Thank you @impvienna.bsky.social for featuring our next career step! The support that Ulrich @hohmannulrich.bsky.social and I received from our postdoc labs (@pauligroup.bsky.social, @juliusbrennecke.bsky.social and @plaschkalab.bsky.social), and now from @imbmainz.bsky.social has been key!
Want to map protein-RNA interactions? Check out our new iCLIP3 protocol. Featuring steamlined library prep and visualisation of protein-RNA complexes without radioactivity! Bioinformatics workflow on top :)
With the Müller-McNicoll and Zarnack labs!
@zarnack-group.bsky.social @mixmue.bsky.social
Our most recent work on the “function and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social
doi.org/10.1016/j.ce...
Read the thread👇 for the highlights of our findings.
How does the piRNA pathway solve the self vs. non-self problem? 🧬
Since piRNAs come from single-stranded RNA, how does the cell choose the right ones? For years, "piRNA clusters" were seen as THE privileged source. But are they really special and earmarked for biogenesis? (1/19)
@lorenzoorts.bsky.social previously worked as a postdoctoral fellow at @impvienna.bsky.social in Austria. She will establish a new lab at IMB to investigate how mRNA translation is activated in the early embryo. Welcome to IMB Laura! 💐
Read more here: www.imb.de/about-imb/ne...
Great to have you as close neighbour and as 2nd fish lab at IMB Laura!
Ulrich’s research will help advance our understanding of RNA biology & gene regulation, as well as how these mechanisms might be altered during viral infections & other diseases.
@hohmannulrich.bsky.social comes from the @impvienna.bsky.social / @imbavienna.bsky.social
www.imb.de/about-imb/ne...
Welcome Ulrich! Looking forward to having you as a colleague here at IMB!
New lab just dropped 👇
www.wur.nl/en/vacancy/f...
Become our new colleague (and next door neighbor) and lead a chair/group/department of Biophysics at Wageningen University. Reach out to me for info and please spread!!!
Recruiting a postdoc for a fun project on insect immunity. An international consortium will study the role of the microbiome&phages in resilience to infection.
Please repost!
www.radboudumc.nl/en/vacancies/160441-postdoctoral-researcher-bioinformatics-of-microbiome-virus-host-interactions-in-insects
Early bird registration deadline of our joint meeting in Potsdam between March 10-13, 2026 - “Joint international meeting of the German @gfeev.bsky.social, Dutch (DSDB), and #SEBD for #DevBio “Development & Regeneration” is approaching fast. Please apply before the 15th of January!
🔍 #AskZebrafish: Does anyone in the US or Canada have any of the following mutant #zebrafish lines and would be willing to share?
tert, klotho, cxcl12a, cxcl12b, cxcr4a and cxcr4b
Any leads would be appreciated! (Yes, we know ZIRC has some frozen but trying to find live)
The Vienna BioCenter Summer School 2026 call is open for talented undergrads, it's a great opportunity for students who are interested in graduate study in the life sciences. Diana Pinheiro from the IMP is recruiting!
https://training.vbc.ac.at/summer-school/
Interested in the unexpected? How about a link between piRNAs and maternal histone mRNAs … Great collab with @sebastianfalk.bsky.social, @koenig-lab.bsky.social and Florian Steiner.
#piRNA #histone #mRNA #maternal #RNAbiology #RNASky
www.biorxiv.org/content/10.6...
If only you’d have had access to AF Miguel…😊. But thanks for kicking off the evo-side of this project at the time!
This doesn’t help my case Ewart😂. I’m very disappointed though about my home country 😊
Thanks for the great (not small!) input into this story Peter.
What a way to start the new year with one more submission to BioRxiv. This one is on how GTSF-1 enable RdRP activity in nematodes (for Piwi aficionados: correct, it does not affect Piwi😊)
www.biorxiv.org/content/10.6...
This nicely shows how the city of Mainz prioritizes bike-usage…one can get sued for not cleaning the walkway along your house, but the city leaves bike trails (but not car lanes of course) covered in ice…
Happy to share two BioRxiv manuscripts from our lab. One on genetic Argonaute interaction and unexpected non-correlation between small RNAs and their targets:
doi.org/10.64898/202...
The second on IDR processing and IDR-mediated Argonaute loading control:
doi.org/10.64898/202...
Merry Xmas😊
Was a pleasure to work together! (And it still is😊)
Very happy to be able to advertise our latest paper:
A genetic framework for RNAi inheritance in Caenorhabditis elegans | EMBO reports www.embopress.org/doi/full/10....
If you are an enthusiastic, motivated and team-oriented life science researcher-in-spé, we are looking for you! We offer excellent science and working conditions. For more info on projects please see. Please help me spread this🙏
www.imb.de/students-pos...
If you are an enthusiastic, motivated and team-oriented life science researcher-in-spé, we are looking for you! We offer excellent science and working conditions. For more info on projects please see. Please help me spread this🙏
www.imb.de/students-pos...