The examples are just ridic.

pkg.yihui.org/gglite/examp...

Hardest going soft launch ever.

#virology #science #vaccines #HepB

New virology pod from the brilliant Florian Krammer.

This week's episode of viroLOGICAL is about hepatitis B (and D) virus.

➡️ Spotify:
open.spotify.com/show/2LxUpjumK…

➡️ Apple Podcasts:
podcasts.apple.com/at/podcast/vir���

➡️ Podigee: https://virological.podigee.io/

The Flanders super group is warming up and it has a new band member 🎸🥁🎹🎤🚴‍♂️ #RVV26

On the balance of knowledge Nature Reviews Immunology - Ruslan Medzhitov shares his thoughts on the balance between generating data and developing theories in immunology, with a focus on exploring the rules that govern...

Free to access link: rdcu.be/e2DCZ

"You can count the feathers of every starling in a flock if you have the right technology but this will give you no insight into their murmurations. "

Britain must not squander its brilliance in biotech - United Kingdom News Beep Biotechnology is one of the most revolutionary, yet underappreciated, technologies of our time. This year alone, it promises personalised cancer vaccines,

Britain must not squander its brilliance in biotech

https://www.newsbeep.com/uk/413224/

Biotechnology is one of the most revolutionary, yet underappreciated, technologies of our time. This year alone, it promises…

dplyr 1.2.0 release notes: replace_values() , recode_values() , replace_when() , filter_out() cran.r-project.org/web/packages... #Rstats

The Carney doctrine Open comment thread on the PM's Davos speech

Carney's speech is brilliant. Here is a transcript. I suspect we will be feeling some serious pain in Canada shortly from the reaction
open.substack.com/pub/paulwell...

A Clinical Trial Nightmare

Prepare for the most groan-inducing CRO drug trial situation you’ve come across in a loooooong time:

Petition to rename the Midlands ‘The Neitherlands’

After you help your boss convert a doc to PDF

What Rosalind Franklin truly contributed to the discovery of DNA’s structure Franklin was no victim in how the DNA double helix was solved. An overlooked letter and an unpublished news article, both written in 1953, reveal that she was an equal player.

On the event of James Watson's death, I highly recommend this 2023 commentary from @matthewcobb.bsky.social and Nathaniel Comfort with crucial new insights into the discovery of the double helix. (And also check out Cobb's brand new biography of Francis Crick) www.nature.com/articles/d41...

The Empire State Building flanked by two buildings, under a broken cloudy sky.

Sometimes you just gotta look up and marvel about the things that human beings have built together.

The driver "managed to contact the control centre at Network Rail and get the train diverted onto the slow line", Calder says. "That was absolutely crucial because this train was scheduled to be travelling through Huntingdon station on the tracks with no platform at 125mph." "It didn't stop in the middle of nowhere, which would have been very difficult." Calder thinks this was handled in the "safest possible way" thanks to the "incredible professionalism from the driver and the police". Train drivers are trained on how to take appropriate action, he adds,

Next time someone tells you that train drivers "just push buttons" show them this from the BBC

Tchéky Karyo, star of Nikita and The Missing, dies at 72 The French actor was known for supporting roles in films that spanned nearly 40 years.

Oh non !
www.bbc.co.uk/news/article...

Pre-print alert! And this one really is a must read for anyone that does spectral #flowcytometry. It is a complete, fully-automated spectral unmixing pipeline that reduces error up to 9000-fold.

Want to get a tough sample, like lung, looking like this? Read more!

www.biorxiv.org/content/10.1...

I am genuinely impressed by large language models - they can absorb disparate components of text into some consolidated view, they can produce extremely good language and - with the right model - translate pretty well between languages and they are an excellent text based UI for humans to use. But..

Nobel Prize in Physiology or Medicine 2025 The 2025 Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries ...

Happy #treg day everyone - congratulations to Mary Brunkow, Fred Ramsdell, Shimon Sakaguchi and to all the immunologists who have contributed to this incredible field. See our collection: www.nature.com/collections/...

For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper?

You got it:
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...

Let's be honest: this is so much better (and more memorable) than the real one could ever have been.

One for the ages.

#LaVuelta25

Each other's? Do tell more...

Hypercapitalist hellhole or city of dreams? Behind the cliches, let me show you the real Dubai | Momtaza Mehri Everyone’s got an opinion about the city. But few in the west know the multicultural, unusual Dubai that I’ve seen up close, says poet Momtaza Mehri

Hypercapitalist hellhole or city of dreams? Behind the cliches, let me show you the real Dubai | Momtaza Mehri

Monoclonal antibodies were invented at the institution I did my PhD - MRC Laboratory of Molecular Biology in Cambridge.

A funny backstory to this is that Milstein tried to patent the finding, however, the MRC concluded that they were unable to "identify any immediate applications"..

Oopsie 🤦‍♂️

Wait, is that Bashar al-Assad???

Someone asked if I had plans for the fall.

It took me a moment to realize they meant "autumn," not the collapse of civilization.

Fifty years of monoclonals: the past, present and future of antibody therapeutics - Nature Reviews Immunology Fifty years ago, Köhler and Milstein introduced the world to hybridoma technology for the generation of monoclonal antibodies. Scientists have subsequently built upon this seminal discovery to develop...

Review @natrevimmunol.nature.com
Fifty years of monoclonals: the past, present and future of antibody therapeutics
www.nature.com/articles/s41...

A C. elegans model for a human disease

This is figure 2 showing how SNAP-tag engineering is aiming for faster and brighter fluorescence labeling

SNAP-tag is a widespread tool for labelling protein for bioimaging. An article published in Nature Chemical Biology presents SNAP-tag2 with increased labelling kinetics and brightness, which translates into a better performance in live-cell super-resolution imaging. go.nature.com/46fMIZd 🧪

I'm excited about a new @biorxivpreprint.bsky.social story that just went live! This one takes a #computational #immunology approach to understanding #tissueresident lymphocytes. The story highlights the extra value mathematical modelling can bring to biology. 🧵1/10

www.biorxiv.org/content/10.1...