Did things settle out for you? May need to tackle the other end of the vessels in microcirculation and go after breaking down microclots.

Works well. Also increases AmpK like metformin.

Happy to speak with others re: metformin use - effectiveness and why it works. Extensive personal use and professional prescribing for LC and inflammatory conditions.

Both better and worse?

Thx for cross-posting

Thread with lots of useful papers measuring proteomics and other topics in #mecfs and #longcovid from 12/30/24.

Links included connect to discussion forum.

evidence that mitochondrial dysfunction is a major aftermath associated with SARS-CoV-2 infection…

the impaired Mitochondria leads to an accumulation of reactive oxygen species (ROS), triggering endothelial dysfunction, and leading to the passage of harmful molecules across the BBB

Detailed measurement from post covid blood. Shows dysfunction in immune / inflammatry response

So you don.t have to leave bluesky…. Here is the results summary

Study from Martha E PharmD.

Treatments that work for patients with me/cfs and long covid. Survey.

x.com/doc4care/sta...

Impact Using online questionnaires validated during in-person medical examinations and including two different control groups, our study compellingly supports and adds to previous clinical observations in the field. Our study provides valuable insights into the prevalence and characteristics of pediatric LCS, highlighting the significant quality of life and functioning impairment compared to control groups. By detecting neutrophilic granulocyte dysfunction in children with LCS, we shed light on a previously overlooked pathophysiological component of the condition. We demonstrate a significant correlation between clinical symptoms and superoxide production, further enhancing our understanding of the underlying mechanisms of pediatric LCS.

New from Hungary:

Long COVID syndrome in children: neutrophilic granulocyte dysfunction and its correlation with disease severity

www.nature.com/articles/s41...

"Neutrophilic granulocyte dysfunction was found in LCS children"

#LongCOVID #LongCOVIDKids #LCKids #PASC
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Thx.

@katha1970.bsky.social please add me to the long covid starter pack list. John Haughton MD, MS @doc4care on x and here.

@doc4care.bsky.social

Thx