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Posts by Rosaura Brisuela

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Exploiting correlations across trials and behavioral sessions to improve neural decoding Animals share common patterns of brain activity across trials and sessions. Exploiting this shared structure improves the prediction of behavior from neural activity, scales across many sessions and b...

“offers interpretable alternatives to deep-learning-based foundation models”

Exploiting correlations across trials and behavioral sessions to improve neural decoding: Neuron www.cell.com/neuron/fullt...

2 months ago 7 5 0 0
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The Infinity Machine A NYT Bestseller and masterpiece on how AI Grew Up by Sebastian Mallaby

How did AI grow up over the past 15 years? The riveting story is expertly told in this exceptional new book THE INFINITY MACHINE by Sebastian Mallaby. Here is the link to our conversation
erictopol.substack.com/p/the-infini...

3 days ago 42 11 3 1
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On April 19, 1898, Camillo Golgi first described what we now call the Golgi apparatus - a structure so striking and unusual that it took more than 50 years for scientists to accept it wasn’t just an artefact.

April 19 is #GolgiDay! Celebrate the cell’s most iconic and best organelle.

4 days ago 49 11 2 2

Everything you wanted to know about #cilia & #signaling in one big beautiful poster format from field thought leaders @wachtenlab.bsky.social & @sorentc.bsky.social- from our just live @jcellsci.bsky.social Special Issue… 🤩🤩🤩

5 months ago 14 8 0 0
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Single-dose psilocybin rapidly and sustainably relieves allodynia and anxiodepressive-like behaviors in mouse models of chronic pain - Nature Neuroscience Hammo et al. show that a single dose of psilocybin rapidly and sustainably relieves both chronic pain and anxiodepressive-like behaviors in mice by restoring prefrontal activity through partial agonism at 5-HT2A and 5-HT1A receptors.

A single dose of #psilocybin induces a rapid and sustained reversal of both mechanical allodynia (pain) and anxiodepression-like states in adult male and female mice

www.nature.com/articles/s41...

6 months ago 9 1 0 0
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We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...

6 months ago 123 44 5 2
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Mitoxantrone Hydrochloride Targets APP and LRRK2 to Improve Neurodegeneration in Parkinson's Models www.biorxiv.org/content/10.1101/2025.10....

6 months ago 1 1 0 0
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Cracking organisms’ energy code Researchers define rules governing how growing microorganisms use energy efficiently

Jonathan Rodenfels @mpi-cbg.de, Pablo Sartori @gimmfoundation.bsky.social, and Tommaso Cossetto identified two thermodynamic rules governing the growth and energy utilization of single-celled organisms. Publication in @nature.com Communications. www.mpi-cbg.de/news-outreac...

6 months ago 24 6 1 1
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🧠📈 Do neurons of a feather flock together? Not quite.

New evidence shows that neurons of the same specific type tend to avoid each other in space, supporting the mosaic hypothesis in the cortex.

📄 Read the @cp-cellreports.bsky.social study: www.cell.com/cell-reports...

6 months ago 38 11 3 0
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The history and future of resting-state functional magnetic resonance imaging - Nature This Review provides an overview of the history of resting-state functional MRI research, which has helped to reveal the spatiotemporal organization of the brain, and discusses how it can contribute f...

When I first started working with resting state fMRI as a postdoc, there was a lot of skepticism about what we could learn from it. 20 years later, it's hard to imagine where the field of neuroscience would be without it. Here's a summary 🧠 www.nature.com/articles/s41...

10 months ago 169 77 1 2

Hey Keri, some nuclei wear their emotions on their chromatin 🤭 I’m sure this is not in any epigenetic text books. Ironically, I captured this on a Lattice Light Sheet microscope a few years back which protects cell from phototoxicity.

7 months ago 35 8 1 0
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Field notes from a weekend PI at the #microscope: vesicle cargo lanes lighting up in real time like @FedEx. This is the ML1N PX domain in a fibroblast. Hot damn, there’s mind-blowing action under the surface of cells: this video shows 2 min of time 🤯 #Cellbio #MicroscopyMonday #SciArt #SciComm

7 months ago 52 13 2 0

Age-related microbiome metabolites modulate splicing and chromatin accessibility in the brain www.biorxiv.org/content/10.1101/2025.10....

6 months ago 3 2 0 0
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Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social

7 months ago 108 46 2 5
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We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

7 months ago 348 118 16 8
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Our new preprint is about the airway epithelium microtubule network, cilia, basal body protein composition, averaging of volumetric fluorescence data, and expansion microscopy.
Four years of very hard work from our very talented Emma van Grinsven. www.biorxiv.org/content/10.1... (1/N)

7 months ago 41 16 2 1
Volume EM uncovers hidden tissue contacts - 2025 - Wiley Analytical Science The largest repository of validated, free and subject-focused e-publications and online seminars in analytical science covering latest techniques, equipment, original research, editorials, and industr...

I wrote an article summarizing our recent findings of beta cell cilia - neuron contacts. It was fun to elaborate a bit on the exploration of #openaccess #volumeEM datasets: analyticalscience.wiley.com/content/arti...

7 months ago 7 3 0 1
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Inside a cerebral organoid: a fluorescent lumen shines through 🧠✨ #FluorescenceFriday

6 months ago 33 4 1 0
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#FluorescenceFriday: getting ready for #GEF25, playing with Ciarán's stunning ExM data

6 months ago 119 21 6 0
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Bringing some more ExM to #FluorescenceFriday with what appears to be a frustrated cell division in fibroblasts.

More details in Alt-text.

6 months ago 49 8 5 0
Image of a fluorescently labeled adult mouse kidney showing AQP2 staining of collecting ducts and connecting segment in green and alpha SMA staining of the arterial tree in magenta. The collecting ducts look like squiggly branches.

Image of a fluorescently labeled adult mouse kidney showing AQP2 staining of collecting ducts and connecting segment in green and alpha SMA staining of the arterial tree in magenta. The collecting ducts look like squiggly branches.

For this #FluorescenceFriday, a gorgeous image of an adult mouse kidney labeled with AQP2 and alpha SMA antibodies. AQP2 (green) marks the collecting duct and distal connecting segment while SMA marks the arterial tree. Courtesy of talented postdoc Sarah McLarnon.

6 months ago 116 32 5 0

Deep Learning-Based Control of Electrically Evoked Activity in Human Visual Cortex www.biorxiv.org/content/10.1101/2025.09....

6 months ago 4 1 0 0
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Heroico colegio militar mexicano #desfile2025

7 months ago 0 0 0 0
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One of the people I'm indebted the most for creating stunningly beautiful #mesoSPIM samples was Martina Schaettin - who tragically passed away in March this year. To honor her memory, Elkhan Yusifov created an award - submit your best #microscopy images & videos! www.linkedin.com/company/mart...

8 months ago 63 16 2 2
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Thomas Deininger uses plastic waste to create sculptures,or should I say,works of Genius!!!!!!

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PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Familial transmission of neural representations for mental arithmetic across two generations | PNAS www.pnas.org/doi/10.1073/...

8 months ago 0 0 0 0
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The neural correlates of ongoing conscious thought Cognitive Neuroscience; Psychology; Techniques in Neuroscience

The neural correlates of ongoing conscious thought: iScience www.cell.com/iscience/ful...

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