L’hypusination de eIF5A contrôle la progression du cancer de la prostate Le cancer de la prostate est le plus fréquent chez les hommes en France et devient particulièrement dangereux lorsqu’il se propage à d’autres parties du

#ResultatScientifique🔎| Des scientifiques ont découvert que la protéine eIF5A, activée par hypusination, agit comme un "chef d’orchestre" et contrôle la progression du cancer de la prostate

✍️ @fredericbost.bsky.social
📕 @natcomms.nature.com
▶️ buff.ly/VEaXQ5C

buff.ly/kbKOfBG

I am thrilled to share the final programme for the upcoming Annual Proteomics Gathering organized by @ypic.bsky.social in Madrid. Check out the QR to see the full list of speakers and talks themes. It looks like a very promising event! 👩🏻‍🔬🔬🎓 Looking forward to welcome all the attendees on April 16th!

Phosphorylation-driven signaling plays a central role in how cells communicate. In this study, together with @saezlab.bsky.social , we revisit the EGF signaling pathway and ask: How well does our traditional understanding hold up in the era of modern phosphoproteomics? www.nature.com/articles/s41...

@map-proteomique.bsky.social was delighted to present its expertise at the first edition of the @crcm.bsky.social Symposium (Centre de Recherche en Cancérologie de Marseille), with contributions from Célia Jardin and Émilie Baudelet

@map-proteomique.bsky.social was delighted to present its expertise at the first edition of the @crcm.bsky.social Symposium (Centre de Recherche en Cancérologie de Marseille), with contributions from Célia Jardin and Émilie Baudelet

Once again a great collaboration with @ibmm-balard.bsky.social @map-proteomique.bsky.social and other !!!

We’re excited to announce the arrival of our new @brukercorporation.bsky.social timsTOF HT — engineered for deeper, faster proteomic discovery at the IMM proteomics platform, part of @map-proteomique.bsky.social

In the heart of winter, the mimosa blooms like fireworks, celebrating the arrival of the New Year.

Happy new year from Marseille proteomics @map-proteomique.bsky.social. Wishing you a great end of year. New year, new projects - follow us in 2026!

Season’s greetings from MAP @map-proteomique.bsky.social. Wishing you happy holidays and a great end of year. New year, new projects - follow us in 2026!

Syntenin Controls Extracellular Vesicle-Induced Tumour Migration by Regulating the Expression of Adhesion Proteins on Small Extracellular Vesicles - PubMed Despite extensive proof for the tumour-supporting function of cancer-derived small extracellular vesicles (sEVs), attributions of pathological effects to specific sEV subpopulations are poorly described. In this study, we aimed to characterise a distinct sEV species under the control of Syntenin, a …

New paper from @crcm.bsky.social & @map-proteomique.bsky.social , in collaboration with the @uni-muenster.de and @uni-goettingen.de !📄🔗 pubmed.ncbi.nlm.nih.gov/40831280/
Excited to have contributed to this work!

📢Publication Alert🌶️! The human cell line phosphoproteome ATLAS has just been released! Generated by analysing 33 human cell lines the team regroup over 200,000 class I phosphosites! Congratulations to @jesperolsenlab.bsky.social! #MagReSyn #Phosphoproteomics #samplepreparation

Proteomics analysis of flow cytometry-based isolated pathogen-containing phagosomes at The University of Manchester on FindAPhD.com PhD Project - Proteomics analysis of flow cytometry-based isolated pathogen-containing phagosomes at The University of Manchester, listed on FindAPhD.com

I have a PhD position available with start date September 2026 at the University of Manchester.

Proteomics analysis of flow cytometry-based isolated pathogen-containing phagosomes

Due to funding requirements, this position is for UK home students only.

www.findaphd.com/phds/project...

Evosep Curiosity Days I Amsterdam, Netherlands Curious on Evosep technology and its applications? Expand your knowledge on February 5 at Evosep Curiosity Days in Amsterdam, Netherlands.

Save the date: February 5th, 2026 for Evosep’s Curiosity Day in Amsterdam.

Expect an exiting full-day program of knowledge sharing, networking, and opportunity to learn more about Evosep technology.

Register here: evosep.com/evosep-curiosity-days-amsterdam-netherlands

A big thanks to Matteo Levy for taking a break from his Master’s exam preparations next week to share, at the monthly MaP meeting, his research conducted during his apprenticeship at @map-proteomique.bsky.social @crcm.bsky.social. An exciting topic: the development of immunopeptidomics!

E-Cadherin Is a Structuring Component of Invadopodia in Pancreatic Cancer - PubMed The appearance of hybrid epithelial-mesenchymal (E/M) cells expressing E-cadherin is favourable for the establishment of pro-invasive function. Although the potential role of E-cadherin in cancer invasion is now accepted, the molecular mechanisms involved in this process are not completely elucidate …

🧬 New from @crcm.bsky.social & @map-proteomique.bsky.social! Dobric A. et al., pubmed.ncbi.nlm.nih.gov/40366255/ J Cell Mol Med 2025: E-Cadherin is a key structural component of invadopodia in pancreatic cancer. Excited to have contributed! 🔬 #PancreaticCancer #CellBiology

@map-proteomique.bsky.social is pleased to present today at the first joint symposium bringing together the prestigious research centers @ciml.bsky.social and @crcm.bsky.social

Discovering Glycosylation-Dependent Protein Function by Thermal Proteome Profiling Protein glycosylation regulates essential cellular processes including protein folding, stability, and cell-cell interactions; however, how aberrant glycosylation impacts protein function and interact...

Congratulations former postdoc @jfhevler.bsky.social (in transit to Roche) and the team on their work using thermal proteome profiling along with glycosylation perturbagens to discover glycan-dependent protein functions at the proteome scale 👏

www.biorxiv.org/content/10.6...

I don't know about a lot of things, but I didn't know about thermal proximity coaggregation (TPCA), or maybe I did. Still, dig it.

www.science.org/doi/10.1126/...

The Human Cell Line Phosphoproteome Atlas: A Deep Empirical Resource Revealing Kinase Activity Landscapes www.biorxiv.org/cont...

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#proteomics #prot-preprint

Isobaric labeling with the @thermofishersci.bsky.social TMT kit is super useful in proteomics! 🧬🔥
#Proteomics #TMT #MassSpec #ScienceLife

Isobaric labeling with the @thermofishersci.bsky.social TMT kit is super useful in proteomics! 🧬🔥
#Proteomics #TMT #MassSpec #ScienceLife

I will be at the 𝐃𝐈𝐀-𝐍𝐍 session @ 𝐓𝐡𝐞𝐫𝐦𝐨 𝐏𝐫𝐨𝐭𝐞𝐨𝐦𝐞 𝐃𝐢𝐬𝐜𝐨𝐯𝐞𝐫𝐞𝐫 & 𝐂𝐨𝐦𝐩𝐨𝐮𝐧𝐝 𝐃𝐢𝐬𝐜𝐨𝐯𝐞𝐫𝐞𝐫 User Meetings in Bremen, Germany, 𝟗-𝟏𝟏 𝐃𝐞𝐜𝐞𝐦𝐛𝐞𝐫. With some cool advances for DIA-NN on Thermo instruments. www.thermofisher.com/de/de/home/e...

Great to welcome Sébastien JeanJean, Senior Sales Manager France at @thermofishersci.bsky.social, to visit our new #OrbitrapAstral mass spectrometer installation today!
Big thanks to our funders — CPER, LNCC, @ibisa.net, Amidex, and @inserm.fr.
#MassSpec #Proteomics @insermpacacorse.bsky.social

Great to welcome Sébastien JeanJean, Senior Sales Manager France at @thermofishersci.bsky.social, to visit our new #OrbitrapAstral mass spectrometer installation today!
Big thanks to our funders — CPER, LNCC, @ibisa.net, Amidex, and @inserm.fr.
#MassSpec #Proteomics @insermpacacorse.bsky.social

In DIA-NN 2.3.0, we have added Deamidation (NQ) as an option in the GUI. There are good reasons for it :) You can try InfinDIA with any number of modifications selected, and check the RT differences between modified vs respective stripped peptides, for each mod - a way to validate peptidoform FDR.

With 𝗗𝗜𝗔-𝗡𝗡 𝟮.𝟯.𝟬 Preview (Academia-only for now), we showcase the transformative new capabilities that have been developed in the past months. Download: github.com/vdemichev/Di...

Recognition of Ovarian Tumor-Derived Non-canonical Peptide Induces Memory-Like Features in Natural Killer Cells Immune cell-based immunotherapy has emerged as a promising strategy for both hematologic malignancies and solid tumors. The adaptive properties of T and B cells, namely, antigen specificity and long-t...

🚨Publication alert🌶️: #Immunopeptidomics is a trending for good reason! A team from @ki.se identify ovarian tumor-derived peptide that induces memory-like features in natural killer cells, paving the way for new cancer immunotherapy strategies! www.biorxiv.org/content/10.1...

Recommendations for Quantitative Data-Independent Acquisition (DIA) Proteomics using Controlled Quantitative Experiments (CQEs) Advances in mass spectrometry and associated computational tools have resulted in the wide-spread adoption of Data-Independent Acquisition (DIA) for proteomics. Experiments using state-of-the-art inst...

Are you using DIA mass spectrometry in proteomics?

We have just put this paper online: www.biorxiv.org/content/10.1...

Here, we came up with some Recommendations for Quantitative Data-Independent Acquisition (DIA) Proteomics using Controlled Quantitative Experiments (CQEs)

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Proteomics Webinar: DIA with FragPipe, DIA-NN, and Skyline
Presenters: Eduard Sabidó and Brendan MacLean
When: Tuesday, September 16, 8am (Pacific Time)
Register Now ... skyline.ms/project/home...

#massspec #proteomics