Thank you Silva and @cruk-cityoflondon for hosting me

Special Issue on Women in Proteomics www.mcponline.org/ar...

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#proteomics #prot-paper

Community benchmarking and evaluation of human unannotated microprotein detection by mass spectrometry based proteomics www.nature.com/artic...



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#proteomics #prot-paper

This has now been published in print! Check it out:
www.science.org/doi/10.1126/...

The Brixen Summer School is back and is, as usual, building up a strong speaker list. Thank you @eupaproteomics.bsky.social @thermofishersci.bsky.social @biognosys.bsky.social @ionopticks.bsky.social @evosep.bsky.social for support!

My lab at the University of Birmingham have a fully funded 4 year PhD position available, focusing on the molecular mechanisms of the Alternative Lengthening of Telomeres (ALT).

Informal enquiries to r.a.broderick@bham.ac.uk

APPLICATION LINK:
sits.bham.ac.uk/urd/sits.urd...

a spongebob squarepants scene with a mailbox and a flower ALT: a spongebob squarepants scene with a mailbox and a flower

Hey @asms.org peeps. I’m running for VP for programs and I’d like your vote. Check out the asms web site for details and you will see an email with voting instructions in the near future. I approach this position with lots of experience organizing scientific conferences & I ❤️ asms. Please re-sky.

Now out! Led by @susana-sousa.bsky.social and Noa Amin, and thanks to our collaborators in the Harrington @icr.ac.uk and Stucki and Choudhary @jc4-jyoti.bsky.social labs

www.cell.com/cell-reports...

Translon: a single term for translated regions. #Translation @natmethods.nature.com

Thank you John and Julie @rna-julie.bsky.social for organising an amazing GRC meeting.

Day 3 of the #GRC on #microproteins #darkproteome with a lively discussion on mega big data analyses for human #ncORFs #sORFs! What a great group!!

Celebrating Al Burlingame's 41 years of the @asbmb.bsky.social Molecular and Cellular Proteomics meeting which he started before "proteomics" was a term. Congrats Al!

Gran Hotel Rey Don Jaime entrance

Loving day 2 of the #GRC for microproteins with @rna-julie.bsky.social! Great talks this mornjng and now I can’t wait until the next one in 2027!

An expanded reference catalog of translated open reading frames for biomedical research www.biorxiv.org/cont...

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#proteomics #prot-preprint

🚨 Has PRIDE helped your research?

Take 15 mins to tell funders why open data matters!
📊 Fill out the EMBL-EBI 2025 survey 👉
www.surveymonkey.com/r/QGFMBH8?ch...

Your feedback helps keep PRIDE open, FAIR & impactful.
🙏 Please share!
#FAIR #OpenData #Proteomics #MassSpectrometry #PRIDE

Integrating Alternative Fragmentation Techniques into Standard LC-MS Workflows Using a Single Deep Learning Model Enhances Proteome Coverage We built and characterised a mass spectrometer capable of performing CID (both beam type and resonant type), UVPD, EID and ECD in an automated fashion during an LCMS type experiment. We exploited this...

I am really pleased we managed to squeeze this story out during #ASMS2025. This is our contribution relating to the fantastic Omnitrap/Orbitrap. What we thought would be a straightforward conversation of our exploris-omnitrap turned into quite a journey. (1/n)

www.biorxiv.org/cgi/content/...

Here's an LC story from our lab. Unlike a lot of stories with titles phrased as questions, it's a maybe/ yes! Interesting for those high throughput proteome people!

ARID1A stabilises non-homologous end joining factors at DNA breaks induced by the G4 ligand pyridostatin ARID1A is a subunit of the BAF chromatin remodelling complex that is frequently mutated in cancer. It is challenging to predict how ARID1A loss impacts cancer therapy response because it participates ...

New preprint from the lab on ARID1A, G quadruplexes, and repair:
www.biorxiv.org/content/10.1...

Data Scientist in Sutton | The Institute of Cancer Research View details and apply for this Data Scientist vacancy in Sutton. Salary : Salary range £39,805 to £49,023 (depending on the experience) Reporting to: Professor Trevor Graham ...

Calling data scientists: we have opening in our Data Science core @icr.ac.uk to lead work around cancer spatial biology and single cell analysis. These are staff scientist type positions, ideal for someone who wants to help drive computational research. Apply here: jobs.icr.ac.uk/vacancies/12...

Congratulations John

Now is the time to reserve your spot for the 2025 Gordon Research Conference on #microproteins. Come join us in beautiful Barcelona in August!

www.grc.org/decoding-mic...

Another fave

Tom Maniatis and Silas Maniatis pose for a selfie at the stand up for science rally in Washington square park.

Had a pretty profound and revitalizing moment in life today. Stood up for science with my father (and lots of other scientists, and non-scientists too). Like my father’s father before us, we Maniatii don’t sit around when fascism is on the move.

Please share. 🙏🏻

Looking forward to welcoming the proteomics community to Liverpool this July!

a baby is crying in a crowd of people with the words `` great job '' written on it . ALT: a baby is crying in a crowd of people with the words `` great job '' written on it .

Congratulations wonderful ladies

PBRM1 directs PBAF to pericentromeres and protects centromere integrity - Nature Communications Centromere fragility can drive tumourigenesis, so protective mechanisms are important. Here, the authors suggest that the PBAF chromatin remodelling complex, which is frequently misregulated in cancer...

Check out our paper here to find out more about PBRM1’s role in protecting centromere integrity: www.nature.com/articles/s41... I’ve loved working with @kezlane.bsky.social, @thedownslab.bsky.social, @lillianwu.bsky.social and everyone else involved on this project over the last several years!

Petition: Cancel Trump’s state visit Stop Trump Coalition

stoptrump.org.uk/petition-can...

Comprehensive discovery and functional characterization of the noncanonical proteome - Cell Research Cell Research - Comprehensive discovery and functional characterization of the noncanonical proteome

Sometimes the #microprotein field needs to police itself.

I rarely see the point in sharing disapproval for published papers. Let bygones be bygones, I suppose.

Several days ago, however, a new paper came out. My assessment is that it is bogus.

#genomics
🧬 💻

1/

www.nature.com/articles/s41...

Donate to Support LA Proteomics Families, organized by USHUPO org USHUPO is raising funds for our LA Proteomics family who have been devastated by the recent … USHUPO org needs your support for Support LA Proteomics Families

The board of USHUPO has set up a GoFundMe site to support USHUPO members in the LA area. In particular these kinds of tragedies can impact graduate students and postdoctoral fellows hard. Here's the link. gofund.me/d73ac63a