Figure showing the principle of the GRACE reporter: CRISPR mutagenesis inactivates an uORF that inhibits GFP translation. Below are several examples of Drosophila wing imaginal discs expressing GRACE and Cas12a+ under control of different Gal4 drivers.

Mapping #CRISPR activity patterns with GRACE. In vivo gene editing sometimes happens at unexpected places. Reporters, such as GRACE, light up the cells that have been mutated. Flies are at @vdrc-flies.bsky.social and plasmids @addgene.bsky.social

Described here:
www.nature.com/articles/s41...

Check out the latest publication of our #SFB1324 members Michael Boutros @michaelboutros.bsky.social and Fillip Port!

Header image for the PhD position "Advanced genome engineering to investigate Wnt signaling in animals."

Join us in Heidelberg for your PhD! If you are excited about CRISPR genome engineering and would like to develop and apply new methods to investigate Wnt signaling in different model systems, than this project is for you. More info here:

my-hbigs.uni-heidelberg.de/site/index.p...

🧪🧬🔬

Universität Heidelberg verteidigt Status als Exzellenzuniversität – Rektorin Frauke Melchior: „Großartige Gemeinschaftsleistung hat zum Erfolg geführt“ www.uni-heidelberg.de/de/newsroom/...
#universität #heidelberg #uniheidelberg #Exzellenzstrategie #ExStra

We are excited that our collaborative research center on Mechanisms and Functions of Wnt signaling has been funded for a third funding period by the German Research Council.

@sfb1324.bsky.social
@uniheidelberg.bsky.social
@hlsalliance.bsky.social
@dfg.de

www.uni-heidelberg.de/en/newsroom/...

This is fantastic! Working in this consortium #SFB1324 has been great support as junior PI, an inspiring atmosphere and exciting science. Thanks to our reviewers for their input, to the #DFG for funding this exceptional Wnt hub, and to our speaker @michaelboutros.bsky.social for driving this forward

The SFB1324 on Wnt signaling with a strong COS contribution has been prolonged by the DFG! Great achievement! (@acebronsp.bsky.social, @josephinebageritz.bsky.social, @lsaunders.bsky.social, @ilohmann.bsky.social, Thomas Holstein, Ulrike Engel, Suat Özbek)

Universität Heidelberg mit drei Förderanträgen für Sonderforschungsbereiche erfolgreich – Für die Verlängerung von zwei transregionalen ... www.uni-heidelberg.de/de/newsroom/...
#universität #heidelberg #uniheidelberg #sfb #forschung #förderung #dfg #lebenswissenschaften #medizin #mathematik

Our #SFB1324 has been granted continued funding for an additional period by the #DFG 🎉🥳
A big thank you goes to all #SFB1324 members for your efforts and we are looking forward to inspiring collaborations.
@michaelboutros.bsky.social

Next Tech Program Open till 2/27/2026
Technician + engineering support for junior research group leaders at Alliance institutions.
👉strengthens junior research group leaders’ technical capacity by funding
👉one full-time technical position.
www.health-life-sciences.de/opportunities/nexttech

Check out the latest publication of our #SFB1324 member Suat Özbek!

Check out the latest publication by our #SFB1324 members. Holger Bastians, @acebronsp.bsky.social and @michaelboutros.bsky.social

Check out our latest publications by our #SFB1324 members Tianzuo Zhan, Jeroen Krijgsveld and @michaelboutros.bsky.social !

Cross-species comparison reveals therapeutic vulnerabilities halting glioblastoma progression - Nature Communications Understanding the growth dynamics of GBMs can help expand therapeutic options. Here, authors use a cross-species computational approach to compare GBM cells to healthy neural stem cells, identifying p...

Check out our latest publication by our #SFB1324 members Ana Martin-Villalba and Anna Marciniak-Czochra! @natcomms.nature.com
www.nature.com/articles/s41...

Michael Boutros @michaelboutros.bsky.social und Josephine Bageritz @josephinebageritz.bsky.social stellen unseren SFB 1324 vor. (only in German)

Check out our latestest publication! @ilohmann.bsky.social @josephinebageritz.bsky.social @michaelboutros.bsky.social
#SFB1324, #Wntsignaling

First preprint from the Bageritz Lab!
Key contributions from Laura Schütze and @mariamusillo.bsky.social, and many helping hands across the lab. Thanks to @cosheidelberg.bsky.social & @sfb1324.bsky.social for their support.
www.biorxiv.org/content/10.1...
#MuscleDevelopment #WntSignaling #SFB1324

@michaelboutros.bsky.social @josephinebageritz.bsky.social

Wissenschaft im Gespräch: Kommunikation der Zellen –
Reihe „Überlebensstrategien“: Wissenschaftler des SFB 1324 stellen ihre Arbeit im Austausch mit Journalist Wolfgang Heim vor – neuer Filmbeitrag abrufbar www.uni-heidelberg.de/de/newsroom/...
#universität #heidelberg #uniheidelberg