Effects of CR ex vivo-cultured mice vibrissa HFs (n = 20). (A) Representative mice vibrissa HFs of each group after 3 d ex vivo-culture. (B) Effects of CR on the increase of HS length of HFs. Data are presented as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001 by two-tailed Student’s t-test. (C) Effects of CR on the cycle transition of HFs.

🧪 A CJNM study reports that Cyperus rotundus extract promotes hair growth by activating Wnt/β-catenin signaling, suppressing TGF-β1/BMP4/DKK1, and increasing IGF1, KGF, and VEGF. Effects confirmed in dermal papilla cells and mouse models.
📖 :
doi.org/10.1016/S187...

#HairGrowth #WntSignaling #CJNM

Get up to speed quickly on your cell biology knowledge with Bioss Pathway Maps

Hand-drawn by a scientific team #Autophagy, #Tumor #Immunology, #MAPK, #WNTSignaling and many others are available to download, print and share at your convenience
👉https://www.stratech.co.uk/our-partners/bioss/#pathways

IARS2 is upregulated in #PDAC, linked to poor prognosis, and drives proliferation and metastasis by stabilizing #βcatenin and activating #WntSignaling, with MSAB reversing these effects, positioning IARS2 as a therapeutic target.

#OpenAccess: doi.org/10.1016/j.ge...

Harnos Lab - Section of Animal Physiology and Immunology ——– What we work withWe study early Xenopus frog embryos: a powerful model for developmental biology. 🐸 Why frogsTheir embryos are large, develop outside the body, and are ideal for live imaging and e...

🚀 Check out the newly improved Harnos Lab webpages!

Our research on cell polarity, development, and migration - now with a fresh look.

👉 ueb1.sci.muni.cz/ofiz/en/harn...

#CellPolarity #DevelopmentalBiology #Xenopus #WntSignaling

Congratulations @michaelboutros.bsky.social and team for obtaining a third funding period by @dfg.de for @sfb1324.bsky.social. The Collaborative Research Center 1324 is a DFG-funded interdisciplinary research consortium of about 60 scientists focused on the Mechanisms and Functions of #WntSignaling

🛠️ New Method online!

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

👉 buff.ly/plPVqud

🖊️ @Dr_Andrology

#Urology #UrOnc #Wntsignaling

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

👉 buff.ly/lYT7Yem

#Drosophila #Development #Wntsignaling

Check out our latestest publication! @ilohmann.bsky.social @josephinebageritz.bsky.social @michaelboutros.bsky.social
#SFB1324, #Wntsignaling

First preprint from the Bageritz Lab!
Key contributions from Laura Schütze and @mariamusillo.bsky.social, and many helping hands across the lab. Thanks to @cosheidelberg.bsky.social & @sfb1324.bsky.social for their support.
www.biorxiv.org/content/10.1...
#MuscleDevelopment #WntSignaling #SFB1324

An overview of the current understanding of #WntSignaling in #StemCells and how Wnt pathway aberrations are associated with diseases, with a discussion on Wnt pathway targeting therapeutics in preclinical & #ClinicalStudies. #medsky
@uchicagocancer.bsky.social

#OpenAccess: buff.ly/0abWFhE

Structural Features of Glypicans and Their Impact on Wnt Signaling in Cancer

In a recent review paper out of the NIH, Hsi-En Tsao and Mitchell Ho detail the modulatory role of #glypicans in #Wntsignaling & underscore the need for better blueprints of glypican/Wnt/Fzd complexes. Check out their mini review 📝 onlinelibrary.wiley.com/doi/full/10....

This #MostRead review discusses the different #WntSignaling pathways and the roles of their signaling components in cellular processes, offering insights into the crosstalk between Wnt signaling and other major signaling pathways. #medsky
#OpenAccess:
www.sciencedirect.com/science/arti...

Researchers from @uchicagocancer.bsky.social summarize the current understanding of #WntSignaling in #StemCells, explore how Wnt pathway aberrations are associated with diseases, and discuss Wnt pathway targeting therapeutics in preclinical & #ClinicalStudies. #medsky
#OpenAccess:

The Wnt pathway regulates stem cell division, differentiation, and even links to diseases like cancer. This review tracks its evolving roles—and its potential for future therapeutic targeting. doi.org/10.1016/j.ge...
#WntSignaling #CellFate #RegenerativeBiology

A review to get you talking! Most downloaded article!

This paper outlines the different variants of #Wntsignaling, including canonical, noncanonical Wnt/PCP, and the noncanonical Wnt/Ca2+ pathway, and provides an overview of its components and the processes that crosstalk with it.

buff.ly/nhbP1ow

The evolving roles of Wnt signaling in stem cell proliferation and differentiation, the development of human diseases, and therapeutic opportunities

A review on the current understanding of #WntSignaling in #StemCells, how aberrations in the Wnt pathway contribute to diseases, with discussion on therapeutics targeting the Wnt pathway in preclinical & #ClinicalStudies. #medsky @uchicagocancer.bsky.social

#OpenAccess: buff.ly/jtlgcnH

Get up to speed quickly on your cell biology knowledge with #Biossusa Pathway Maps

Hand-drawn by a scientific team #Autophagy, #Tumor #Immunology #MAPK #WNTSignaling and more

Available to download, print and share
🔗https://www.stratech.co.uk/our-partners/bioss/#pathways

#pathwayposter #bioscience

Insights into the role of the Wnt signaling pathway in the regeneration of animal model systems

by K. S. Walczyńska, L. Zhu and Y. Liang

ijdb.ehu.eus/article/2201...

🔑 Wnt signaling pathway #WntSignaling, #RegenerationBiology, #AnimalModels, cell fate determination #CellFate, #TissueRepair

MAFB-mediated CEBPA regulated human urothelium growth through Wnt/β-catenin signaling pathway

This study shows that MAFB-mediated CEBPA expression is involved in the pathogenesis of #Hypospadias via Wnt/β-catenin signaling. #TranscriptionFactor

#OpenAccess: www.sciencedirect.co...

#MedicalResearch #Genetics #urology #cellbiology #hypospadias #Wntsignaling #ScienceInnovation