Photo of a laboratory bay full of computers. Three scientists stand around one computer on one side of the bay, while two scientists examine another computer on the other side.
I love it when I walk into the lab and it looks like a staged photo for collaborative science.
The CASP experiment is about to start - and is still short on challenging prediction targets. Ligand complexes, RNA, …
“The Year in Clinical Micro” at #ESCMIDGlobal2026 🔬
A devastating reality:
⚠️ >3 million children died from AMR-related infections in 2022
🌍 Highest burden in Southeast Asia & Africa
💊 Many deaths linked to Watch & Reserve antibiotics
AMR is already a leading cause of child mortality.
IRB Barcelona invites applications for Group Leader positions in Chemical Biology (one) and Structural Biology (one) as part of its strategic effort to strengthen molecular sciences. The successful candidates will join a highly multidisciplinary and collaborative institute with strong expertise in cancer and metastasis, ageing and cell reprogramming, metabolism, cell differentiation, signal transduction, and gene expression, working at the interface of structural and computational biology, chemistry, and biology. IRB Barcelona is embedded in a vibrant scientific ecosystem and maintains close collaborations with major research infrastructures such as the Barcelona Supercomputing Center (BSC) and the ALBA Synchrotron, as well as leading research centres, universities, and hospitals in Barcelona. About IRB Barcelona IRB Barcelona (www.irbbarcelona.org) is a multidisciplinary research institute where scientists collaborate to address fundamental biomedical questions and unmet medical needs. The Institute currently hosts more than 500 members from around the world across 27 research groups. How to apply Applications should include a CV, letter of intent, brief (2-page) research proposal, and the names and contact details of at least three referees. Applications must be submitted via https://recruitment.irbbarcelona.org no later than 22 May 2026, quoting reference GL/26/01 (Chemical Biology) or GL/26/02 (Structural Biology). The successful candidates are expected to join in Q4 2026 or 2027, with flexibility depending on individual circumstances. For Informal enquiries, please contact the chair of the Search Committee (Prof. Xavier Salvatella, at xavier.salvatella@irbbarcelona.org) and for details and updates on the selection process please contact the Head of People at (irbglcall@irbbarcelona.org)
Was just asked to spread the word about this position.
Structural biology and Chemical Biology positions in Barcelona, one of the great cities of the world!
www.irbbarcelona.org/sites/defaul...
We are looking for an individual to develop a very strong, extramurally funded research program in Pharmacology or Toxicology relevant to Animal Sciences or Veterinary Sciences.
See the ad for more info.
#Canada #Academia #AcademicSky #USASK #Saskatchewan #WCVM
wcvm.usask.ca/departments/...
No needle needed: Health Canada approves epinephrine nasal spray for treating anaphylaxis caused by allergic reaction, by Nicole Thompson www.thecanadianpressnews.ca/national/mee... via @thecanadianpressnews.ca.web.brid.gy
Topline results of daraxonrasib's ph3 trial for pancreatic cancer are so incredible I can hardly believe them.
Median overall survival of 13.2 vs 6.7 months with chemo, i.e. ~doubling survival.
I'd like to see the data but this may be the biggest breakthrough in pancreatic cancer we've ever seen.
Congratulations to Dr. Andrew Boozary on receiving the 2026 Governor General's Innovation Award!
Dr. Boozary is recognized for leading the creation of Dunn House - Canada’s first hospital-led supportive housing initiative. Learn more about his work:
https://innovation.gg.ca/winner/dunn-house/
I am excited to share our most recent work collaborating with @centriolelab.bsky.social and @stearnslab.bsky.social to look at the ciliary base of mammalian multiciliated cells w/ cryo-ET, XL/MS, and U-ExM www.biorxiv.org/content/10.6...
Cover image of the Journal of Cell Science, Volume 139, issue 6. Image shows a red macrophage on top of a grid of blue dots. Inside of the macrophage are green and yellow dots.
My labs most recent publication made the journal cover! The image shows a macrophage trying to eat blue dots that mimic dying cells. Red is the macrophage membrane, orange and green are two proteins involved in removing dead cells.
The paper: journals.biologists.com/jcs/article/...
There’s too much bad news these days
To uplift you, check out this @ourworldindata.org story on how cervical cancer rates have declined greatly among younger generations with vaccination!
ourworldindata.org/hpv-vaccinat...
Work in progress: sars-2 clearly increases risk of tuberculosis activation in central Ontario, on a timeline that is consistent with T cell injury. It does not impact risk of non tuberculous mycobacterial infections
More follows
The call including details on how to apply: https://candidate.hr-manager.net/ApplicationInit.aspx?cid=3010&ProjectId=158638&DepartmentId=19974&MediaId=4917 Job and person profile: https://employment.ku.dk/documents/job-and-personal-profile-bio.pdf
Do you want to be my boss?
We are looking for a new Head of Department
Our Department covers biology broadly, from molecular biophysics 🧬 to ecology 🌱 & biodiversity 🐋, and coordinates teaching in several BSc and MSc programmes🧑🎓
Located in Copenhagen, one of the world's most liveable cites 🚲 🌞 🌥️
I am so sad to hear about the passing of the great Andreas Engel. Beyond the many scientific accomplishments of his career, he was an amazingly kind person who helped me a lot when I started my own lab. You will be missed Andreas 💔
Dear colleagues, With deep sadness I share the news that Andreas Engel passed away last Wednesday, at the age of 82, after a courageous fight against an aggressive caner. Only half a year ago, he was out hiking in the Italian mountains with his wife Barbara, walking 160 km in a single week. Andreas trained as a physicist in Bern, Switzerland, before heading to John Hopkins University in Baltimore for his postdoctoral work. He then led a research group at the Biozentrum in Basel, and in 1985 took on the role of a group leader in research and development at Ilford Ltd. in Fribourg, Switzerland. In 1987, he joined forces with his colleague Ueli Aebi to establish the Maurice E. Müller Institute at the Biozentrum of the University of Basel. Together, Ueli and Andreas served as professors for structural biology there for almost a quarter century, leaving a lasting mark on the field of structural biology as we know it today. Andreas Engel was a true pioneer. He was among the first to apply atomic force microscopy (AFM) with the tip operating under water, and one of the earliest researchers to perform 3D reconstructions using scanning transmission electron microscopy, achieving remarkable high-resolution maps of porin 2D crystals by STEM. He became a leading expert in membrane protein 2D crystallization, and his group played a key role in the determination of the first aquaporin structure, in collaboration with Peter Agre and Yoshinori Fujiyoshi. As he approached retirement from Basel, Andreas founded the Center for Cellular Imaging and NanoAnalytics (C-CINA) of the University of Basel, which in 2009 operated among others one of the very early Titan Krios instruments. From 2008 also held a professorship at Case Western Reserve University, Cleveland, followed by a position at TU Delft in the Netherlands in 2013. In 2020, he was among the founding members of CryoWrite, a company in Basel that he led as CEO until recently. His contributions to science, to the tools of str…
Photo of Andreas Engel
Sad news on the passing of Prof. Andreas Engel, a pioneer in the field of cryo-EM (shared with the 3DEM community by Henning Stahlberg).
Andreas' kindness, warmth, and enthusiasm for science and his colleagues will be missed.
John and Gautier pose for a photo
Gautier in group meeting with a party hat and party noisemaker
Gautier loses an arm wrestle with Thamiya
A young Gautier wraps David in bubblewrap
It was @courbongautier.bsky.social 's last day in the lab.
He came to the lab, did some amazing science, had some fun, and leaves an accomplished scientist. And he leaves this place, and all of us here, changed for the better.
Bob at the Grand Hotel in Stockholm ahead of the Nobel Prize ceremony in 2017
Bob giving a speech at Joachim Frank's 80th (+2) year birthday celebration in New York in 2022.
Truly the end of an era.
Bob Grassucci in New York was one of the pioneering cryo-EM facility managers during the field's development (along with the likes of Deryck Mills in Germany, John Berriman in the UK, Bill Tivol in California, and others). Unsung heros of the cryo-EM resolution revolution.
A great human being.
RIP Stephen Lewis
A group photo of Ian with some of his friends from the 20th Floor Molecular Medicine. Everyone but Ian is wearing a tee shirts with a picture of Ian on it.
Congratulations on a great PhD defense @ianyyen.bsky.social!
I've enjoyed discussing the finer points of cryo-EM with Ian, being on his advisory committee, and having him as an "honorary group member" these past 6 years.
We've been we've been working on this for quite a while now (hopefully published soon). Grateful to @proftracypalmer.bsky.social for concinving me & @lislowe.bsky.social that mycobacteria produce inter-bacterial toxins. Team science, led by @sambenedict5.bsky.social www.biorxiv.org/content/10.6...
Bittersweet moment to give special thanks to the late Kiyoshi Nagai and former colleague for developing the yeast expression system that we made use of in this work.
Our work with the Brun lab on the in situ architecture of the Caulobacter crescentus Tad pilus machine is published in mBio. Amazing collaborative effort led by James Iarocci @jamesiarocci.bsky.social
FACT OF THE DAY. 26 March 1953. In a huge medical breakthrough, US medical researcher Dr Jonas Salk announced that he had created the first polio vaccine. Polio cases fell from 58,000 per year in 1952 to 6,000 by 1958. Salk’s vaccine was replaced by a new one developed by Albert Sabin in 1962.
Tuberculosis remains the world’s deadliest infectious disease.
Lalita Ramakrishnan’s group, @cellbiol-mrclmb.bsky.social & @medcambridge.bsky.social, studies how TB thrives, including what drives its drug tolerance.
Read more: new.express.adobe.com/webpage/GdOa...
#LMBintheNews #WorldTBDay #EndTB
One of the deadliest diseases in history is still here. TB kills 1.3M people every year.
On #WorldTBDay, VIDO researchers are advancing vaccines, drug targets, and new models to help stop TB.
Read more: www.vido.org/news/2026/ad...
@usask.ca @jeffchenmycolab.bsky.social
#WorldTBDay #TB
Happy to announce that my institution, @irbbarcelona.org, is opening two group leader positions, 1 in chemical biology and 1 in structural biology, to strengthen our expertise in molecular sciences: please spread the word !
We filled day 3 with #cryoEM core knowledge covering foundational math, data analysis workflows and reconstruction practicals.
Thanks to Fred Sigworth, David Jeruzalmi & Collin McManus (#cryoSPARC practical).
Ready for a deeper dive?
cryoemprinciples.yale.edu
@structurabio.bsky.social
At the #cshlcourses cryo-EM course, Rich Waldo from @structurabio.bsky.social gave us a tutorial on cryoSPARC and did a fabulous job! I was honored to be used for an Einstein from noise demo.
