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🔬IGMM (CNRS/ Univ Montpellier) is hiring Group Leaders in Innovative Biology. @cnrsbiologie.bsky.social @cnrs.fr @umontpellier.bsky.social
📅 1 May–15 June 2026
📩 search2026@igmm.cnrs.fr
📎Full information 👇
#LifeScience #MolecularBiology #Research #PI #CNRS

5 days ago 24 28 1 0
Coordination des instances du Comité National

#ESR #VeilleESR

Tribune de la C3N du #CNRS signée par plus de 700 scientifiques (membres du comité national, directrices et directeurs d'unités) pour alerter une nouvelle fois sur les conséquences des coupes budgétaires

c3n-cn.fr/2026/04/10/b...

3 days ago 26 19 1 1

Thanks to everyone involved and to our funding agencies @fr-genomics.bsky.social @agencerecherche.bsky.social @frm-officiel.bsky.social
5/5

5 months ago 1 1 0 0

📣📣 Deadline approaching 📣📣 (Please re-post)

If you are thinking of starting (or moving) your lab, do not miss the opportunity to apply to join us at the
@i2bcparissaclay.bsky.social

Diversity of topics, interdisciplinary environment and excellent platform support! Recommended!

1 week ago 9 12 0 0

We identify robust replication origins functioning across diverse chromosomal contexts and confirm a model where CFSs arise from transcription-dependent repression.
Congrats to J. Mandelbrojt, C. Tonnerre-Doncarli, T. Baret, A. Masson. A great collaboration with M. Debatisse.

1 week ago 0 0 0 0
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Transcription at an inducible common fragile site reveals replication origin strength hierarchy Abstract. While genome-wide analyses in vertebrates suggest that transcription negatively regulates replication origin activation, thereby shaping the land

Our latest publication is out! @narjournal.bsky.social

academic.oup.com/nar/article-...

1 week ago 4 2 1 1
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A H3K27me3 reader complex couples H3K27me3 accumulation to nascent transcription of transposable elements in Paramecium - Genome Biology Background The ability to deposit histone H3K27-trimethyl (me3) marks is essential for transcriptional repression by Polycomb Repressive Complex 2 (PRC2). This is largely attributed to Polycomb repres...

Our latest publication is now out at Genome Biology!
link.springer.com/article/10.1...

We uncover a unique association between a H3K27me3 reader complex and active transcription.
A thread with our key findings: (1/8)

#TEsky #Polycomb #transcription #smallRNAs

1 week ago 86 39 4 3
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📢 Institut Jacques Monod Seminar

📅 April 14th
📍 Institut Jacques Monod

Next week, Andre Nussenzweig will present the Institut Jacques Monod seminar "Genome Stability in Post-Mitotic and Mitotic Cells"

➡️ buff.ly/UtRw3py

2 weeks ago 0 2 0 0
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#JobOffer

💼 Professeur en stabilité du génome
📍Institut Jacques Monod
📆 1e septembre 2026

Les candidatures sont ouvertes jusqu'au 3 avril 2026 16h🔗 u-paris.fr/recrutement-...

1 month ago 5 12 0 0
Spatial controls of homology search Homologous recombination is a conserved DNA double-strand break (DSB) repair pathway that uses an intact dsDNA molecule as a template. A filament of the RecA/Rad51 protein family catalyzes the search for this homologous template, in a process that minimally requires the collision of these two partners in the nuclear space. Orthogonal methodological developments recently revealed that this search for homology is a choreographed process under control by both 3D chromatin organizers of the structural maintenance of chromosomes (SMC) family and the structure and dynamics of the RecA/Rad51 filament. Here we review these advances that establish a novel framework for homology search, highlight the commonalities and distinctions between search facilitation strategies in eukaryotes and bacteria, and discuss outstanding open questions.

Our OA author manuscript is always available here: hal.science/hal-05520503

1 month ago 0 1 0 0
Flyer for symposium: https://ctrlepiedit.sciencesconf.org/

Flyer for symposium: https://ctrlepiedit.sciencesconf.org/

Very excited to announce the FIRST symposium on epigenome editing! These tools are becoming widely used in mol bio, ag & therapy. It's time to bring leaders together to discuss this rapidly growing and exciting field. And why not in Paris! Please register & share! (1/2) ctrlepiedit.sciencesconf.org

1 month ago 84 58 3 6

The Epstein files document what many women researchers have long experienced but rarely seen laid bare so starkly: exclusion operating behind closed doors, shaping who gets funded, invited, mentored, and taken seriously. How many of these networks, norms, and gatekeepers remain in place?

1 month ago 4443 1806 46 58

Or as the doi is not yet active ... www.biorxiv.org/content/10.6...

2 months ago 0 1 0 0

A beautifully crafted summary of the extraordinary discovery in the lab of my @mrclmb.bsky.social colleague @philholliger.bsky.social of a tiny RNA that can replicate RNA.

2 months ago 18 9 0 0
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Molecular basis for the activation of Aurora A and Plk1 kinases during mitotic entry - The EMBO Journal The evolutionarily conserved, intrinsically disordered protein Bora is critical for initiating the activation of mitotic kinases. Once phosphorylated at Ser112 by Cyclin A-Cdk1 kinase, phospho-Bora ac...

AlphaFold modeling & new assays for mitotic kinase activation in E. coli (#MITOKINAC) reveal molecular basis of specific Aurora A & PLK1 activation through Bora during mitotic entry
Lionel Pintard @ccdlab.bsky.social et al
#RefereedPreprint ℅ @reviewcommons.org
link.springer.com/article/10.1...

2 months ago 10 7 1 0
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Required reading for everyone interested in the synthetic genomics - @adrianwoolfson.bsky.social's new book 'On the Future of Species' is published today (Charles Darwin's birthday). Here's the man himself at the launch last night at @dauntbooks.bsky.social in Marylebone. (Photo: Wes Robertson)

2 months ago 3 2 0 0
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Events for February 2026 06-07 July 2026 | Munich, GermanyDNA Replication and Its Impact on Genome and Chromatin MaintenanceWe are RepliFate, a European Training Doctoral Network dedicated to understanding how DNA replication...

We go live!!!

Join us Munich July5-7th to hear exciting research on #Replication by leaders in the field

AND !! registration is FREE 🥳 (but mandatory) - we hope to see many in Munich 🍺 @helmholtzmunich.bsky.social

@replifate.bsky.social @epicrossborders.bsky.social

replifate.eu/event/meetin...

2 months ago 32 28 1 1
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DNA translocation by the CMG helicase: the helical inchworm model Abstract. In all cells, hexameric helicases drive the unwinding of parental chromosomal DNA at replication forks to provide the single-stranded DNA templates required by replicative DNA polymerases. D...

Happy to share our perspective on the DNA translocation mechanism by the CMG helicase.

DNA translocation by the CMG helicase: the helical inchworm model url: portlandpress.com/biochemsoctr...

2 months ago 16 10 0 1
Portail Emploi CNRS - Offre d'emploi - Poste de chercheur postdoctoral en trafic membranaire fondamental et sécrétion du collagène (H/F) Assurez-vous que votre profil candidat soit correctement renseigné avant de postuler

Postdoc job alert at Institut Jacques Monod in Paris! Interested in fundamental membrane trafficking? We seek a postdoc to study collagen secretion as a model for core principles of how cells and their environment build each other. emploi.cnrs.fr/Offres/CDD/U...

2 months ago 16 25 0 1
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Gladys Mae West obituary: mathematician who pioneered GPS technology She made key contributions to US cold-war science despite facing huge barriers as a Black woman.

No joke: I got angry hate mail today for writing an obituary of a Black woman scientist—because the person felt she did didn’t deserve the recognition.

Which just makes me want to share it again: www.nature.com/articles/d41...

2 months ago 48307 19770 1367 809

Ever worried that your redesigned genome might not replicate as expected? Well, help is at hand with a genome language model for replication origins from the Boemo lab (with a little bit of help with some new data from us). www.biorxiv.org/content/10.6...

2 months ago 3 1 0 0
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✍️ The Cadoret Lab contributed to a new publication

📖 @natcomms.nature.com
📃 DNA methylation and lncRNA control asynchronous DNA replication at specific imprinted gene domains
🔗 www.nature.com/articles/s41...

2 months ago 3 3 0 0
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📣 16th edition of the French 3R meeting “Replication, Recombination, Repair” - Registrations are open!

📆 May 18 to 21, 2026
📍 Belambra Club Presqu’île du Ponant in La Grande-Motte, France

🔗 www.2026.3r-meeting.fr/page/home/

2 months ago 4 3 0 2
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Do you work in DNA replication, genome maintenance, chromosome organisation, chromatin maintenance, or a related field? 🧬

Join us for #EESReplication – submissions are welcome from researchers at all career stages!

20 – 23 October 2026
Send your abstract by 28 July: s.embl.org/ees26-13-bl

2 months ago 11 4 1 0
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We are hiring!

2 months ago 24 36 2 3
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Great response so far for the DNA Repair Meeting in April 2026 ! 🧬

A few poster spots are still available.

✨ Early-bird registration extended to February 28th
✨ New invited speakers added: check the site: dnarepairmeeting-egmond2026.com

Don’t miss this outstanding meeting!

3 months ago 6 4 1 0
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Ploidy-dependent modulation of DNA replication kinetics in Xenopus DNA replication in multicellular organisms follows a tightly regulated spatio-temporal program. Although the mechanisms underlying this replication program remain only partially understood, studies in...

We are pleased to share a new preprint on BioRxiv www.biorxiv.org/content/10.6....
@ijmonod.bsky.social.

3 months ago 1 2 0 1
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The Expanding Roles of Homologous Recombination Proteins in Genome Stability
@labvincenzo.bsky.social review how RAD51 shields DNA from nucleolytic processing, promotes fork reversal, suppresses replicative DNA gaps, binds abasic sites to avert cytotoxic conversion
link.springer.com/article/10.1...

3 months ago 18 5 0 0

I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!

3 months ago 154 63 23 2
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One more upcoming appointment with great science via the Genome Integrity Italian Network (GiiN). Don't miss it, just join via the link 👇

3 months ago 11 7 0 1