I’m grateful for the opportunity to share our work at the “67th Annual Drosophila Research Conference” in Chicago, IL.

I was also honored to serve as a poster judge for the “Cell Division and Cell Growth” session.

#DROS26 #Drosophila #Wnt #Hox #Adipose #Metabolism #EMBOReports

Fly Bayou group at #DROS26! It was great to see many of them in person after monthly virtual meetings.

Adipocyte heterogeneity regulated by the Bithorax Complex-Wnt signaling crosstalk in Drosophila - EMBO Reports Adipocytes play essential roles in lipid metabolism and energy homeostasis, with regional differences affecting their functions and disease susceptibility. However, the mechanisms underlying this regi...

Regional adipocyte heterogeneity supports metabolic homeostasis, yet mechanisms remain unclear. This study reveals that the interplay between Wnt/Wingless signaling and Hox proteins (Abd-A and Abd-B) defines the regional heterogeneity in Drosophila.

link.springer.com/article/10.1...

Transcriptional Regulation of Lipid Metabolism by Wnt Signaling and Hox Protein Cues
#Drosophila

Transcriptional coupling of telomeric retrotransposons with the cell cycle The life cycle of telomeric retrotransposons is transcriptionally linked to host cell-cycle machinery via E2F1 in Drosophila.

Transcriptional coupling of telomeric retrotransposons with the cell cycle | Science Advances www.science.org/doi/full/10....

Distinct effects of CDK8 module subunits on cellular growth and proliferation in Drosophila url: journals.biologists.com/dev/article/...

bpod.org.uk/archive/2024...

Wnt/Wingless signaling promotes lipid mobilization through signal-induced transcriptional repression | PNAS www.pnas.org/doi/abs/10.1...

Liu, M., Xie, X. J., Li, X., Ren, X., Sun, J., Lin, Z., Hemba-Waduge, R. U., Ji, J. Y. (2023). Transcriptional coupling of telomeric retrotransposons with the cell cycle. bioRxiv, www.biorxiv.org/content/10.1...

Hemba-Waduge, R. U., Liu, M., Li, X., Sun, J. L., Budslick, E. A., Bondos, S. E., Ji, J. Y. (2024). Metabolic control by the Bithorax Complex-Wnt signaling crosstalk in Drosophila. bioRxiv, www.biorxiv.org/content/10.1...

Wnt/Wingless signaling promotes lipid mobilization through signal-induced transcriptional repression | PNAS The Wnt/Wingless signaling pathway plays critical roles in metazoan development and energy metabolism, but its role in regulating lipid homeostasis...

Liu, M., Hemba-Waduge, R. U., Li, X., Huang, X., Liu, T. H., Han, X., Wang, Y., Ji, J. Y. (2024)s. Wnt/Wingless signaling promotes lipid mobilization through signal-induced transcriptional repression.. JProc Natl Acad Sci U S A, 121(28):e2322066121 www.pnas.org/doi/abs/10.1...