El nou edifici que acolllirà grups de recerca de 5 centres #BISTCommunity i enfocat en medicina de precisió va prenent forma.

👉www.ara.cat/societat/horitzo-2028-gr...

🔬A new mechanism explains how protein production is regulated in #FattyLiver under metabolic stress.

📰 Science Advances

✍️ Raúl Méndez, Eulàlia Belloc, Vittorio Calderone, Mercedes Fernández, @idibaps.bsky.social @ptck72.bsky.social et al.

➡️ https://shorturl.at/UtRVB

📌 DOI: 10.1126/sciadv.aea4125

Our linker histone H1 paper is featured on the cover of the April 10 issue of #ScienceAdvances.
www.science.org/doi/10.1126/...
A molecular dynamics simulation of nucleosomes and linker histone H1, with single-H1 trajectories (background). 🎉 Full cover caption: www.science.org/toc/sciadv/1...

Postdoc position:Computational Biophysics of Disordered Proteins, Lindorff-Larsen group, University of Copenhagen, Denmark https://tinyurl.com/REWIRE-PD Deadline May 3rd, 2026

We are hiring a postdoc in computational biophysics and machine learning studies of intrinsically disordered proteins

We aim to study the function of IDPs by combining CG MD, ML and bioinformatics in collaboration with @tanjamittag.bsky.social & @rhp-lab.bsky.social

tinyurl.com/REWIRE-PD

📢 We are #hiring!

#GroupLeader positions open at #IRBBarcelona in #ChemicalBiology and #StructuralBiology.

Application deadline: May 22, 2026

𝗚𝗿𝗼𝘂𝗽 𝗟𝗲𝗮𝗱𝗲𝗿 𝗶𝗻 𝗖𝗵𝗲𝗺𝗶𝗰𝗮𝗹 𝗕𝗶𝗼𝗹𝗼𝗴𝘆
➡️ shorturl.at/1tE3n

𝗚𝗿𝗼𝘂𝗽 𝗟𝗲𝗮𝗱𝗲𝗿 𝗶𝗻 𝗦𝘁𝗿𝘂𝗰𝘁𝘂𝗿𝗮𝗹 𝗕𝗶𝗼𝗹𝗼𝗴𝘆
➡️ shorturl.at/eKiJn

#IRBJobs #Jobs #AcademicSky

#paper #highlight February 2026

Oligomerization enables the selective targeting of an intrinsically disordered region by a small molecule

By S. Bielskutė-García et al in #ScienceAdvances

sbe.es/highlights-p...

@xsalvatella1.bsky.social
@irbbarcelona.org
@icreacommunity.bsky.social

📢 Upcoming Seminar | Join us for a plenary seminar this Friday, with Dr. @adelaljord.bsky.social, from the @crg.eu.

🤝 Hosted by Dr. @xsalvatella1.bsky.social 

Register here ➡️ https://shorturl.at/A9VMZ

#IRBBarcelona #Seminar

Happy to announce that my institution, @irbbarcelona.org, is opening two group leader positions, 1 in chemical biology and 1 in structural biology, to strengthen our expertise in molecular sciences: please spread the word !

More specifically: @icreacommunity.bsky.social, @irbbarcelona.org, @ageinves.bsky.social, @themarkfdn.bsky.social, @contracancerinv.bsky.social, @caixaresearch.bsky.social, @erc.europa.eu

Oligomerization enables the selective targeting of an intrinsically disordered region by a small molecule The druggability of intrinsically disordered regions.

Our work on how oligomerization can enable selectively targeting intrinsic disorder with small molecules is now out in Science Advances: www.science.org/doi/10.1126/...). Congratulations Stase Bielskute and @borjaml.bsky.social and thanks to the collaborators and funders !

IDPSeminars is back TOMORROW! Come see @tanjamittag.bsky.social and @xsalvatella1.bsky.social ! Not to be missed!!

STI1 domain engages transient helices to mediate Dsk2 phase separation and proteasome condensation - The EMBO Journal Ubiquitin-binding shuttle proteins are important components of stress-induced biomolecular condensates in cells. Yeast Dsk2 scaffolds proteasome-containing condensates via multivalent interactions wit...

Yeast ubiquilin Dsk2 scaffolds proteasome-containing condensates under stress via multivalent interactions – @castanedalab.bsky.social et al show how dynamic interactions among its STI1 domain & transient helices in its disordered region promote its phase-separation
link.springer.com/article/10.1...

The image illustrates a principle by which homomers can be polymerized by mutations or by multivalent small molecules.

In 2017 we showed that homomers evolve on the edge of supramolecular self-assembly. Here we show how to exploit this vulnerability so that ALL homomers can become bona fide drug-🎯. Delighted that Aim 3 of our @erc.europa.eu finally polymerized! Manuscript: 👉 rdcu.be/e27bT

An excellent review on a fascinating topic !

Join 2026 BPS Lecturer Lewis Kay on Tuesday, February 24, 2:00 PM - 3:00 PM at #bps2026 for an informal discussion. Dr. Kay will share insights from his scientific career—from pioneering discoveries to lessons learned along the way—and reflect on how the field continues to evolve

📢  #MAINFRAME Symposium comes to Barcelona!

Experts in #AI, computational chemistry & small-molecule #DrugDiscovery meet to advance open, large-scale screening for 2,000+ human proteins.

📆 Mar 18–19
📍 Ateneu Barcelonès
ℹ️ https://shorturl.at/1aKKS

@ptck72.bsky.social

Head, Advanced Genomics Technologies Core Facility (Ref. CF/26/01) - IRB Barcelona IRB Barcelona invites applications for the position of Head, Advanced Genomics Technologies Core Facility. The successful candidate will report to the Director, Technology Strateg...

🚨WE'RE RECRUITING AT @irbbarcelona.org !!!!

--- ADVANCED GENOMICS FACILITY MANAGER ---

An amazing opportunity to help us drive the fight against cancer and other aging-related diseases using Single-cell, Bulk and Spatial genomics!!!!

APPLY NOW!!!!

recruitment.irbbarcelona.org/jobs/7124180...

How does protein folding change inside biomolecular condensates?

Our new preprint put forwards a framework for predicting this!! 🥳🥳🥳🥳 work by the talented @nathanieldhess.bsky.social

16 de enero de 2026 YouTube video by IRB Barcelona

You can’t miss this video we shared today during the tribute to Dr. #JoanGuinovart.

Today, the scientific community, institutional leaders, colleagues, friends, and family gathers to honour the life and legacy of the founder and first director of #IRBBarcelona.

🎥 youtu.be/_SJ5Rudj2ik

Unfortunately this seminar has been cancelled. We will reschedule it and share the details here.

📌 Don't miss our plenary #seminar this week, with Prof. Edward Lemke, from @unimainz.bsky.social. 

Host: Dr. @xsalvatella1.bsky.social, #IRBBarcelona

Register here ➡️ https://shorturl.at/I58yN

🧪

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.

Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.

Apply now ➡️ www.crick.ac.uk/careers-stud...

Snapshot of a condensate near a lipid membrane with Swedish Research Council and Malmö University logos.

I'm hiring for a PhD position at Malmö University, Sweden!

The project will focus on molecular modelling of proteins, lipids, and biomolecular condensates at cell membranes.

More details and application form: tinyurl.com/4zm92365

Please feel free to share!

@vetenskapsradet.bsky.social | @mau.se

Thank you Fundación @bbvaenespana.bsky.social for supporting our collaboration with Michael Krieg of @icfo.eu !

Is the Sagrada Família a Masterpiece or Kitsch? In the century since Antoni Gaudí died, his wild design has been obsessively realized, creating the world’s tallest church—and an endlessly debated icon.

Antoni Gaudí’s vision for the Sagrada Família, a church that’s been under construction for nearly 150 years, was never universally liked. George Orwell called the church “one of the most hideous buildings in the world.”

Autism is on the rise: what’s really behind the increase? Nature - RFK Jr has vowed to find out what’s responsible, but scientists say he is ignoring answers from decades of research.

RFK Jr has vowed to find out what’s responsible for the rise in autism diagnoses, but scientists say he is ignoring answers from decades of research

go.nature.com/47R4brs

Are you a computational biologist who loves the outdoors & is thinking about faculty positions? Then check this out:
eeik.fa.us2.oraclecloud.com/hcmUI/Candid...

Tenure track position at the University of Wyoming - amazing colleagues, beautiful landscape, and fantastic work-life balance.

New paper on transcription factor phase separation published from my colleague Aseem Ansari's and my lab: Reconciling competing models on the roles of condensates and soluble complexes in transcription factor function authors.elsevier.com/sd/article/S...

Exciting news: our Board of Trustees has appointed @monicabettencourt.bsky.social as the CRG's new Director. Prof Bettencourt-Dias is expected to take up the post in 2026, replacing Dr. Luis Serrano, who will continue to maintain a research group at the institute.
www.crg.eu/en/news/moni...

Four University colleagues win prestigious Royal Society of Chemistry prizes Four University of Manchester colleagues have been honoured by the Royal Society of Chemistry for their outstanding contributions to the chemical sciences.Professor Igor Larrosa has been selected to r...

Congratulations to RSC-ESR group committee member Adam Brookfield and his colleague, Dr Muralidharan Shanmugam, for winning the RSC Technical Excellence Prize for their operations of the EPSRC NRF for EPR in Manchester, UK. www.manchester.ac.uk/about/news/f...