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Posts by Sophie de Carné (she/her)

You will be working in a rich, collaborative scientific environment, interacting with cancer scientists and bioinformaticians, and working closely with clinical teams.

For more info, follow this link 👇
adum.fr/as/ed/voirpr...

2 weeks ago 1 0 0 0

🚨 PhD opportunity in my and @phileast.bsky.social's labs.

If you are excited about exploring data generated by the latest genomic technologies to enhance our understanding of lung cancer biology, apply by 28/04.

Please share 🙂

#CancerResearch #jobinscience #PhD #Bioinformatics #Genomics

2 weeks ago 5 2 1 0
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We are recruiting!

We are searching for an exceptional postdoctoral fellow to lead the single-cell phenoscaping efforts of the REWIRE-CAN Cancer Grand Challenge @cancergrand.bsky.social

For more information and to apply please visit: www.ucl.ac.uk/work-at-ucl/...

3 weeks ago 8 8 0 0

Our circadian clock and cancer chronotherapy, a terrific
@scripps.edu review, open-access, related to below!
jci.org/articles/vie...

2 months ago 151 41 0 1

Cytokines are tricky to study, let alone in vivo. New tool to study cells that respond to cytokine receptor activation

3 months ago 11 2 0 0

Beautiful work and beautiful images.

3 months ago 1 0 0 0
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Somatic evolution following cancer treatment in normal tissue - Nature High-depth sequencing of non-cancerous tissue from patients with metastatic cancer reveals single-base mutational signatures of alcohol, smoking and cancer treatments, and reveals how exogenous factors, including cancer therapies, affect somatic cell evolution.

Nature research paper: Somatic evolution following cancer treatment in normal tissue

go.nature.com/48MhLvf

4 months ago 12 5 0 0

And we do not yet know what the impact will be on the rest of their lives.

4 months ago 1 0 0 0

If you are interested in how oncogenic RAS signalling influences the immune landscape of lung adenocarcinoma, our latest preprint on the subject is out on @biorxiv-cancer.bsky.social

#KRAS #lung #immuno-oncology #preprint 🧪

4 months ago 5 2 0 0
Video

Paul Nurse describing the main job of a PI

(From ‘The Thinking Game’, 2024)

5 months ago 181 53 2 5
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A plastic EMP1⁺ to LGR5⁺ cell state conversion as a bypass to KRAS-G12D pharmacological inhibition in metastatic colorectal cancer Abstract. Inhibitors of the oncogene KRAS hold promise for treating metastatic CRC (mCRC). Here we show that a selective, covalent small molecule inhibitor of the active (ON) conformation of RAS-G12D,...

Cell plasticity as a mechanism to evade KRAS inhibition in colorectal cancer.

#KRAS #CellPlasticity #CancerStemCell 🧪

5 months ago 8 1 1 0

Bravo 👏

5 months ago 1 0 0 0
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#ESMO25
Adam Gripping of @mdanderson.bsky.social discusses association of improved OS in #NSCLC and #Melanoma with administration of a mRNA COVID vaccine

Translational work showing mechanism of increased INF-alpha leading to immune priming

Phase III in development… @oncoalert.bsky.social

6 months ago 3 3 0 0
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Quels progrès dans la lutte contre le cancer ? (2/2) - L'Humanité Les pathologies cancéreuses sont mieux combattues. Les récentes découvertes liées à l’immunothérapie viennent s’ajouter aux thérapies ciblées et géniques. Mais des questions se...

📰 « Quels progrès dans la lutte contre le cancer ? »

@humanite.fr publie la tribune du Pr Fabrice André qui appelle à renforcer la prévention et la recherche sur les causes environnementales et comportementales des cancers, chez les 20-40 ans.↩️

www.humanite.fr/en-debat/can...

6 months ago 1 1 0 0

Yet another example of negative commercial determinants of health

Sunbeds are known to be especially harmful for young population, increasing the risk of skin cancer by 59%, according to the cancer research agency

And again yet, some governemnts prioritise (commercial) profir over (public) health

6 months ago 2 1 0 0

If you are looking for a postdoc position in a great lab with a fantastic PI, the Caswell Lab at UCL is recruiting 🙂

6 months ago 4 2 0 0
This is figure 5 from Wildfire smoke exposure and mortality burden in the US under climate change. It shows the mortality impacts of wildfire smoke PM2.5 and estimated mortality due to smoke 533 PM2.5 under future climate scenarios.

This is figure 5 from Wildfire smoke exposure and mortality burden in the US under climate change. It shows the mortality impacts of wildfire smoke PM2.5 and estimated mortality due to smoke 533 PM2.5 under future climate scenarios.

Increases in wildfires are expected to cause a notable increase in premature deaths, according to two studies in Nature.

go.nature.com/4mynauQ
go.nature.com/4nJoxI5
#medsky ⚒️ 🧪

7 months ago 19 10 1 0

Debbie, you cumulate successes! Congratulations. This is amazing.

7 months ago 1 0 1 0
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Très astucieux. Bravo !

7 months ago 1 0 0 0
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Gustave Roussy toujours 1er centre français et 1er centre européen en oncologie L’excellence de Gustave Roussy est une nouvelle fois reconnue par le magazine américain Newsweek, qui a classé l’Institut 1er centre de lutte contre le cancer en France et en Europe, et parmi les meil...

📰 @gustaveroussy.fr toujours 1er centre français et 1er centre européen en #oncologie.

En savoir plus ⤵

7 months ago 2 2 0 0

Congrats Emma! Well deserved.

7 months ago 0 0 0 0
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📰 La chercheuse Sophie de Carné nommée Young Leader par le Conseil franco-britannique.

7 months ago 3 1 2 0

Congrats @inigolanda.bsky.social and Stephanie Corgnac 👏

7 months ago 5 1 1 0

📌 great thread.

7 months ago 1 0 1 0
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Lung Cancer Prevention Laboratory Pioneering research in lung cancer to improve diagnosis, treatment and prevention

I am excited to announce that my laboratory @ucl.ac.uk is now open!

We are hiring so please contact us if you are interested.

www.caswelllaboratory.com

1 year ago 17 8 4 0

Very nice. Where is it?

8 months ago 0 0 0 0
The Past, Present and Future of Immunology Research – with Caetano Reis e Sousa
The Past, Present and Future of Immunology Research – with Caetano Reis e Sousa YouTube video by Francis Crick Institute

Join Caetano Reis e Sousa (@reisesousalab.bsky.social) as he describes how our immune systems work and his team’s research into better understanding dendritic cell receptors. www.youtube.com/watch?v=nBC9...

9 months ago 10 3 0 0
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I agree, Larry. I use it to get an overview of something I am not familiar with. I brainstorm with it. I ask for “brutally honest feedback” with a prompt that makes it challenge my thinking.
But I would not make it generate text from scratch. I have tried and it isn’t helpful.

8 months ago 1 0 0 0
Writing is thinking - Nature Reviews Bioengineering On the value of human-generated scientific writing in the age of large-language models.

Writing is thinking. A reminder on why scientists write, and why we should continue writing in the era of large-language models by Nature Review Bioengineering

@natureportfolio.nature.com
www.nature.com/articles/s44...
#AI #LLM 🧪

8 months ago 32 7 1 0

Depends… Does it have a bottle opener? 😅

9 months ago 1 0 1 0