An all-in-one pipeline for the in vitro discovery and in vivo testing of Plasmodium falciparum malaria transmission blocking drugs - Nature Communications Current antimalarials often fail to target mature stage V gametocytes. To aid antimalarial drug discovery, the authors present a preclinical malaria transmission-blocking drug research platform, using engineered parasites, that facilitates the screening for gametocytocidal compounds in vitro and the evaluation of transmission-blocking drug activity in vivo.

An all-in-one pipeline for in vitro discovery and in vivo testing of Plasmodium falciparum #malaria transmission-blocking drugs

@SwissTPH.ch #DrugDiscovery #parasitology

SSPH+ | Generative Artificial Intelligence for Data Analysis: A Randomised Controlled Trial in a Public Health Research Institute ObjectiveTo assess the competence of students and academic staff to use generative artificial intelligence (GenAI) as a tool in epidemiological data analyses...

Can ChatGPT help analyse public health data?

A new study by Swiss TPH explored this question through a randomised controlled trial with students and researchers, using ChatGPT to conduct an epidemiological data analysis as a tool or an addition to R/Stata.

New pipeline to identify malaria transmission-blocking drugs The Biomolecular Screening Facility has contributed to a successful collaborative study led by Till Voss (Swiss Tropical and Public Health Institute, University of Basel), resulting in the development of a robust, all in one pipeline for the discovery and testing of transmission blocking drugs against Plasmodium falciparum. This multidisciplinary effort combines a high-throughput in vitro assay with a novel in vivo model, enabling systematic evaluation of compounds that target mature stage V gametocytes - the only forms of the parasite that infect mosquitoes.

New pipeline to identify drugs blocking #malaria transmission

It combines a high-throughput in vitro assay & a mouse model, enabling evaluation of compounds targeting the parasite's mosquito-infecting forms

@SwissTPH.ch

Heartfelt congratulations to Aita Signorell for having been awarded the venia docendi by @unibas.ch!

With a background in Biology (MSc) and Biochemistry (PhD). Aita has spent the past 15 years working in clinical and implementation research.

The program for the 4th Swiss Implementation Science Conference «True IMPACT – Providing Innovation for Patients and the Public» (🗓️ 12–13 Feb 2026) is now live. 📢 Register & check out the schedule: www.ifis.uzh.ch/en/impact.html @nursing.mstdn.nursing.unibas.ch.ap.brid.gy @impact-swiss.bsky.social

Unser 4. Jahresbericht ist publiziert. Möglicherweise das detaillierteste nationale Monitoring von nichtionisierender Strahlung weltweit.
@swisstph.ch

Swiss TPH Welcomes High Number of New Students With the start of the autumn semester, Swiss TPH warmly welcomes over 90 new master’s and PhD students from across the globe. The number of master’s students increased over the last years, reflecting ...

Welcome to the new semester!
Over 90 students from 30 countries started at Swiss TPH 👋🏼

👥 Meet our consortium partners!
Finally, we are introducing the team from @swisstph.ch - another driving force in MARKOPOLO. They play a key role in assessing the #health #effects of #environmental #pollutants.

🔗 Read more about the work: markersofpollution-markopolo.eu/about/consor...

The autumn semester @unibas.ch is about to start and we are looking forward to welcoming 25 new PhD and 62 new MSc students at @swisstph.ch. About 1/2 of our students are from abroad, many from the Global South, creating a unique diverse atmosphere and many opportunities to learn from each other! 🌍🤗

Read more here: www.nccs.admin.ch/nccs/en/home...

Ces résultats rappellent que la chaleur peut avoir de graves conséquences sur la santé et qu’il faut agir pour mieux protéger la population.
Le Swiss TPH suit la mortalité liée à la chaleur en Suisse pour l’Office fédéral de la santé publique (OFSP) et l’Office fédéral de l’environnement (OFEV).

De nouvelles données du monitoring sur la mortalité liée à la chaleur montrent : En 2024, environ 326 décès ont été attribués à la chaleur – moins que durant les deux étés précédents, en 2022 et 2023. L’été a été le sixième plus chaud jamais enregistré en Suisse, surtout au sud du pays.

Die Ergebnisse zeigen deutlich, dass Hitze die Gesundheit belastet und es Schutzmassnahmen braucht.
Das Swiss TPH führt das Monitoring der hitzebedingten Todesfälle in der Schweiz im Auftrag des Bundesamts für Gesundheit (BAG) und des Bundesamts für Umwelt (BAFU) durch.

Neue Zahlen aus dem Monitoring der hitzebedingten Sterblichkeit zeigen: Im Sommer 2024 waren etwa 326 Todesfälle der Hitze geschuldet – weniger als in den zwei vergangenen Sommern 2022 und 2023. 2024 war der sechstwärmste Sommer in der Schweiz, mit besonders hohen Temperaturen in der Südschweiz.

The findings highlight the health impact of heat and the urgent need for protective measures.
Swiss TPH monitors heat-related mortality in Switzerland on behalf of the Federal Office of Public Health @bag.admin.ch and the Federal Office for the Environment @bafu.admin.ch.

Rising temperatures & more frequent heatwaves are a clear signal of #ClimateChange – and pose a risk to public health.

New figures of the heat-related mortality monitoring show:
- In summer 2024, ~326 deaths were attributed to heat – less than in 2022 & 2023
- Summer 2024 was the 6th warmest in 🇨🇭

Swiss-African Science Diplomacy is a powerful driver of innovation and global collaboration. In our new Policy Brief you learn:
1️⃣How science diplomacy advances foreign policy and scientific cooperation.
2️⃣How Swiss-African science diplomacy can be strengthened.

New policy brief: Towards Strong Swiss–African
Science Diplomacy

Key recommendations:
1️⃣ Align strategies & clarify roles
2️⃣ Strengthen presence & secure funding
3️⃣ Drive learning through evidence-based monitoring

Read the full policy brief here: www.swisstph.ch/fileadmin/us...

Release schema-48.0 · SwissTPH/openmalaria Release of OpenMalaria version 48.0. Update to version 48.0: https://github.com/SwissTPH/openmalaria/wiki/SchemaUpdateGuide Changelog: https://github.com/SwissTPH/openmalaria/wiki/Changelog Example...

🚨 OpenMalaria v48.0 is out!
Major updates:
🦟 Elimination model improvements
📊 Heterogeneous intervention coverage
📝 Simplified XML structure
🔗 Download: github.com/SwissTPH/ope...
📋 Changelog: github.com/SwissTPH/ope...
#OpenMalaria #GlobalHealth #Epidemiology @thekidsau.bsky.social @swisstph.ch

Drs Fredros Okumu, Joel Odero, Derek Charlwood, Bart Knols & April Monroe discuss safeguarding #malaria control gains in #Africa through #species #sanitation & #structural #resilience. @sbohvm.gla.ac.uk‬ @uofglasgow.bsky.social‬ @swisstph.ch‬ @unibas.ch

www.cell.com/trends/paras...

Investitionen in die globale Gesundheit lohnen sich, gerade für die Schweiz Der Rückzug der USA aus der Finanzierung globaler Gesundheitsprogramme setzt Menschenleben aufs Spiel. Auch die Schweiz wird die Folgen spüren – und sollte darum ihre Führungsrolle verstärken.

The article was originally published as an opinion piece in @nzz.ch am Sonntag: www.nzz.ch/nzz-am-sonnt...

Global Health: A Smart Investment for Switzerland Eva Herzog, President of the Swiss TPH Board of Governors, reflects why it's time for Switzerland to lead and not retreat in global health.

Efforts to improve global health have saved millions of lives worldwide – however, this progress is under threat.

@evaherzog.bsky.social, President of the Swiss TPH Board of Governors, reflects why Switzerland should continue to invest in global health, taking a leading role rather than retreating.

Globale Gesundheit: Eine kluge Investition für die Schweiz - Eva Herzog Ständerätin

Das Engagement für die globale Gesundheit hat in den letzten Jahrzehnten weltweit Millionen von Leben gerettet. Warum dieser Fortschritt auf dem Spiel steht und welche Folgen das für den globalen Sünden, aber auch für uns hat, zeige ich im Meinungsbeitrag in der NZZ am Sonntag auf: bit.ly/4l3Nn3A

An image showing the ARTIC and Pathoplexus logos connected by blue lines, with the text "Hiring: post-doc/software engineer" and "Global open-source pathogen tools" and "Join Swiss TPH, Work on ARTIC2 and Pathoplexus, Basel, Switzerland"

📢New job posting!📢
Are you excited by the idea of building global infrastructure to make pathogen sequencing more accessible, interpretable, and equitable? 🧑🏻‍💻🧬

My group at @swisstph.ch has an opening working with ARTIC2, @pathoplexus.org, & Loculus - read on!

1/5

Early Testing for Legionella Improves Pneumonia Care Routine testing for Legionella in hospitalised pneumonia patients leads to faster diagnosis and better-targeted treatment, according to a new study led by the Swiss Tropical and...

Routine testing for Legionella in hospitalised pneumonia patients leads to faster diagnosis and better-targeted treatment – says a new study led by Swiss TPH.

The findings also underscore the need to promote shorter antibiotic treatment in line with national guidelines.

@unibas.ch

📬 The first MARKOPOLO Insights #newsletter is out, featuring consortium news, publications, new report by EEA and much more! 🗞️

🔗 Read the full newsletter here: mailchi.mp/82b8fd2e0d51...

@martinroosli.bsky.social @eea.europa.eu @swisstph.ch @climair.bsky.social @concentris.bsky.social

Temporal Change of Outdoor RF-EMF levels in four European Countries: a Microenvironmental Measurement Study Over the past two decades, the amount of transmitted mobile data has increased rapidly. It is unknown whether the implementation of the new technologi…

New data, same message❗ Mobile phone radiation📳 in outdoor environments in Belgium 🇧🇪, The Netherlands 🇳🇱, Spain 🇪🇸 and Switzerland🇨🇭 has not increased between 2016 and 2023 despite x-fold increase in mobile data transfer.
@etaineu.bsky.social @swisstph.ch

www.sciencedirect.com/science/arti...

A map of the socioecological system

The Lancet Commission on #OneHealth is live ⚡

“[The Commission] provides a cutting-edge appraisal of where One Health has come from, where it is now, and what a viable future should be”, say authors.

Explore findings & 10 expert recommendations ⤵️
bit.ly/3TMa6WD

Combination Therapy Improves Treatment of Whipworm in Children A new clinical trial led by Swiss TPH and partners on Pemba Island, Tanzania, has shown that combining moxidectin with albendazole is far more effective than current standard...

A new clinical trial led by Swiss TPH & partners on Pemba Island has shown that combining moxidectin with albendazole is more effective than current standard treatment for whipworm infections in school-aged children.

The results might inform future guide-lines for soil-transmitted helminth control.

Digital Tools Help Identify Severe Illness, but Hospital Access Remains a Barrier A study coordinated by Swiss TPH, in collaboration with partners in India, Kenya, Senegal and Tanzania, has found that introducing pulse oximeters and digital clinical decision...

Pulse oximeters and digital clinical decision support tools are transforming how we identify severe illness in children – but only if they reach the care they need.

Findings from the Tools for Integrated Management of Childhood Illness (TIMCI) consortium ⬇️