A new study published in the April issue of #GENETICS uses #yeast model to identify that the ribosomal protein ASC1 reduces TDP-43 toxicity via autophagy, revealing a new regulatory pathway in the neurodegenerative disease ALS.
🔗 buff.ly/bzGCa41
Latest study from @hainerlab.bsky.social probes the functions of nucleosome remodeling complexes in higher-order chromatin organization in mice.
Learn more in the April issue of #GENETICS: 🔗 buff.ly/cDQzB28
Short-read sequencing data processing requires multiple steps and computational tools, impacting #reproducibility across projects and laboratories.
WeavePop, a #reproducible and #scalable workflow, helps align, explore, and analyze genomic variants.
🔗 buff.ly/hPlv0jJ
Quality assessments of long-read sequences remain challenging due to the lack of tools that carry all the metrics for genome evaluation.
PAQman integrates multiple commonly used tools and metrics, allowing quality assessment within a single framework.
🔗 buff.ly/Wy29wEJ
The April issue of #G3journal highlights two new #bioinformatics tools 🛠️ 🧬
👉 PAQman for applications in long-read sequencing and
👉 WeavePop for short-read sequencing data
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On April 18, 1905, William Bateson introduced the term “genetics,” giving identity to the study of heredity and variation. 🔗 Learn more: buff.ly/Yuqq3aC
📢 NEW GENOME ALERT
A haplotype-aware and chromosome-scale genome assembly of allohexaploid tall fescue, a predominant forage and turf grass, provides a new resource for mapping and functional genomic studies.
Paper in #G3journal: 🔗 buff.ly/bDwi3Ro
The April issue of #G3journal features a genetic selection-based prediction model that incorporates fixed environment-specific means, random additive genetic effects, and other factors to develop training sets for rice, barley, and maize breeding programs.
🔗 buff.ly/Q6k2ETZ
How do haploid and diploid cells evolve in the natural isolates of the #yeast Saccharomyces cerevisiae?
Dive deep into these experimental results that reveal genetic signatures in haploid vs diploid strains.
Paper in #G3journal: 🔗 buff.ly/J4kixfb
📖 Read this important perspective piece in the April issue of #GENETICS that outlines the limitations of Mendelism in genotype-phenotype mapping and advocates for new experimental paradigms to understand context-dependent genetic effects.
🔗 buff.ly/4OAZJS2
Congrats Michael O’Connor, recipient of the 2026 Edward Novitski Prize! An emeritus professor at the University of Minnesota, he remains active at the bench and has made foundational contributions to developmental genetics.
🔗 Read more: buff.ly/6zuD34Y
@alecchristensen.bsky.social et al. evaluated the ability of commercially available medium-density and high-density SNP arrays for white-tailed deer to accurately identify genetically related individuals within a wild population. 🦌
Learn more in #G3journal: 🔗 buff.ly/gau5c1f
📢 NEW GENOME ALERT
The first high-quality genome sequence of Umbelopsis nana, a soil saprotrophic fungus, presents a crucial resource for the genus as well as for future comparative genomic studies.
Learn more in #G3journal: 🔗 buff.ly/lLsLa62
Get ready for #Yeast26! Show your yeast pride at Asilomar with official #Yeast26 merch—featuring shirts, mugs, notebooks, totes, and more inspired by the community that makes this meeting so special. 🛍️Browse the collection: buff.ly/2MMgPPn
PS. Early registration closes tomorrow!
A new study investigated the molecular mechanisms underlying responses to sublethal thermal stress in aquatic #Daphnia by examining shifts in gene expression and fitness.
Find more in #G3journal about the pathways involved in the thermal stress response. buff.ly/kROeC6q
A new study investigates the relationship between double-stranded breaks and genome-wide mutation patterns in #Drosophila. 🪰
Read about the findings in #G3journal: buff.ly/MMSuAZ6
🚨TODAY AT 5PM 🚨
Don’t miss Nicole Torosin’s “From academia to entrepreneurship” workshop where she discusses her path toward a non-traditional academic career.
Make sure you’re registered: buff.ly/h6wieKi
New research in #G3journal probed the relationship between nutrition and reproduction in #Drosophila, identifying a core transcriptional response to diet and a female-specific, diet-dependent transcriptomic program in response to mating. 🪰
Paper from @maxreuter.bsky.social: 🔗 buff.ly/7WKQ7Oy
Join us in congratulating @schacherer.bsky.social of @unistra.fr, recipient of the 2026 GSA Medal! His work pushes the boundaries of population and functional genomics.
🔗Read more: buff.ly/HpkjVzU
NOVA proteins as key regulators of alternative splicing and circular RNA regulation.
In #G3journal, read about the #transcriptomic and mutant analyses showing the regulations of age-associated circular RNAs by RNA-binding protein NOVA-1 in #Celegans.
🔗 buff.ly/X7hccKj
The April issue of #GENETICS features a genetic screen in #yeast Saccharomyces cerevisiae, identifying MFB1 as a suppressor gene of #mitochondrial protein import clogging—with implications on cell growth inhibition and mitochondrial DNA destabilization. 🔗 buff.ly/fdrvCqE
📢 NEW GENOME ALERT
In #G3journal, @krynadachowska.bsky.social et al. present a high-density linkage map and chromosome-level assembly of spruce bark beetle, revealing an inversion-rich genome that will be a crucial resource for comparative genomic studies. 🪲
buff.ly/7hiXUon
Learn about the new SNP-based genetic linkage map of stevia anchored to a chromosome-scale genome assembly and how it will identify new molecular markers and breeding strategies to improve our favorite sugar substitute.
Paper in #G3journal: 🔗 buff.ly/R7nFNR5
🪰 #Dros26 has come and gone—and what a week it was. From a guitar-fueled opening to buzzing poster sessions, researchers shared advances in fly biology, behavior, and beyond. Thanks to all who joined us for another incredible year!
Read a recap by @gnemeth.bsky.social on G2G: buff.ly/x31gZFt
New research in #G3journal demonstrates that #Celegans oocyte surface proteins EGG-1 and EGG-2 are not required for fertilization but play an important role in the organization of eggshell structural components and oocyte plasma membrane proteins.
🔗 buff.ly/FDaqw8g
Updates from:
Caenorhabditis Genetics Center
CartograPlant, @treegenes.bsky.social
CottonGen
Genome Database for Vaccinium
GrainGenes
Legume Information System
@maizegdb.bsky.social
Mondo
PeanutBase
@pombase.bsky.social
@sorghumbase.bsky.social
SoyBase
@tairnews.bsky.social
@xenbase.bsky.social
2/2🧵
Databases and knowledgebases are essential infrastructure for genetics research—supporting data sharing, discovery, and reproducibility across the field.
Read the full April #GENETICS issue: buff.ly/YQA781d
1/2🧵
The latest work in #GENETICS from @hoosierflyman.bsky.social presents the natural history, taxonomy, physiology, and genome of Leptopilina malgretoutensis, a virulent parasitoid of #Drosophila dunni flies from the Eastern Caribbean. buff.ly/H4imAKC
In #GENETICS, @christophrau.bsky.social et al. leveraged the diversity in the mouse Collaborative Cross population to identify novel genetic loci associated with cardiac physiology and pathophysiology through variation in β-adrenergic stress responses. buff.ly/6ji4zuj
Nicole Torosin from GNR8 Personal Training is discussing her nontraditional career path in “From academia to entrepreneurship” next week on April 14. Learn how she built a company offering hyperpersonalized, genetically guided training services. Register now: buff.ly/m0BBnzk