Stimulating keynote from @jojofoth.bsky.social on advancing phage therapy for chronic respiratory infections in cystic fibrosis, addressing key translational challenges from clinical pathways and phage biobanking to delivery, diagnostics, and public engagement at #Microbio26.
At the first day of #microbio26
Great to see exciting work from @megllewellyn.bsky.social on how expression context shapes the protection provided by bacterial defence systems. Comparing chromosomal and plasmid-encoded systems highlights how regulatory architecture influences defence effectiveness.
DefensePredictor: A machine learning model to discover prokaryotic immune systems
#microbiology #prokaryotes #CRISPR #MicroSky
@science.org
www.science.org/doi/10.1126/...
@multidefence.bsky.social bowling is on. The quality is perhaps lacking
Highlights from our recent participation!
Members of the Multi-Defence Consortium presented both talks and posters on phage defence systems — showcasing exciting progress across the field.
Great discussions, great science, and we’re excited to share more soon!
#MicroEvo25
@multidefence.bsky.social
Antibiotics & phage infectivity
www.findaphd.com/phds/project... (4/4)
🦠 Defence systems & AMR
www.swbio.ac.uk/files/2025/1...
www.swbio.ac.uk/programme/ho... (3/4)
🧬 MADS–CRISPR interaction www.findaphd.com/phds/project... (2/4)
🔬 Interested in bacterial immune systems & AMR, or how antibiotics affect phage infectivity?
Three SWBio DTP PhD project opportunities linked to the MultiDefence consortium are now open (1/4)
#PhD #DoctoralTraining #ResearchCarrers #LifeSciences #phagesky #AMR #microsky #PhDPositions
More info & tickets see poster and link: sites.exeter.ac.uk/vanhoutelab/...
(2/2)
🦠🧬 Join us for a workshop on Phage Therapy in Liverpool (25 Nov 2025)!
A 1-day free event bringing together clinicians, academics, regulators & industry to discuss the future of phage therapy; happening in tandem to a 2-day focus meeting on Microbial Evolutionary Dynamics (1/2)
Happily representing @multidefence.bsky.social at the #EESMicrobiology in Heidelberg!
Come to my poster if interested in prophage-mediated phage defence!
Also don't miss @emgoodall.bsky.social's talk today, and @alekseiagapov.bsky.social and @davvi36.bsky.social posters!
Presenting a poster about Pseudomonas defence systems at #EESMicrobiology in Heidelberg. If you happen to like it, don't forget to check out our consortium @multidefence.bsky.social
Great to get together in Manchester last week for our consortium’s annual meeting – halfway through our 5-year collaboration! Inspiring discussions, exciting updates, and lots of ideas ahead. Excited for what’s next! 💡🔬🤝 #Science #Microbiology #TeamScience
Edze Westra kills viruses @multidefence.bsky.social
As part of the @multidefence.bsky.social consortium, we worked with a globally curated dataset of >4,000 P. aeruginosa (from 10.1126/science.adi0908) to reveal differences in the number and composition of defence systems between isolates from (and not from) cystic fibrosis cases 2/n
Great to be in Manchester for the annual @multidefence.bsky.social meeting, with Luna and Simon!
Passing through the Borders on the train to Manchester for the annual @multidefence.bsky.social meeting
This work was led by the incredible @charlotteechong.bsky.social 💻 🧬 as part of the @multidefence.bsky.social sLoLa consortium funded by @ukri.org BBSRC and in collaboration with a wonderful set of new (and old!) colleagues 9/n
www.findaphd.com/phds/project...
A funded PhD studentship is available for a joint project between my lab and @andreashaag.bsky.social @uniofstandrews.bsky.social
🔬 Three fronts in bacterial defense!
At EMBO symposium this week in Paris, our PIs showcased:
• @mfwhite2.bsky.social: cyclic nucleotide defence signaling
• Prof. Stineke Van Houte: prophage warfare in P. aeruginosa
• Prof. Tim Blower: autoregulating toxins & phage defence
We had fantastic poster presentations at the EMBO symposium the Immune System of Bacteria in Paris this week
Coming back to Microbial Warfare session today we have @charlotteechong.bsky.social giving a talk about "Genomic analyses to infer defence system interactions among global Pseudomonas aeruginosa populations" at 12:15
@samriddhigupta.bsky.social gave her poster presentation today at #Microbio25 about discovering new counter-defence systems in prophage genomes
Second poster session starting soon #Microbio25
We also have a couple of poster presentations today 255 from @drramabht.bsky.social, 282 from @anna-k-richmond.bsky.social, 062 from Meg Llewellyn and 068 from Jasmine Thomas-Campbell. All cool stuff about defence systems!
