Using mosquitoes to vaccinate bats could curb the spread of deadly diseases Nature - But scientists say there are practical and ethical challenges to overcome before the strategy could be deployed in real-world settings.

Vaccinating bats could reduce the risk of these viruses infecting other animals, including people

go.nature.com/3NcXrwh

I'm thrilled to share that the first paper from my PhD is out today in @cp-immunity.bsky.social!
Here, we investigated how phagocytes, such as macrophages, handle microplastics (MPs) during their normal functions.
www.sciencedirect.com/science/arti...

🫁 AIR 2026 registration closing 19th Jan

Focused on respiratory infection, microbiomes and immunity, with amazing speakers.
Incl genomics, single-cell, spatial and systems approaches.

📍 Wellcome Genome Campus
📅 11–14 Feb

coursesandconferences.wellcomeconnectingscience.org/event/air-20...

Super interesting paper on Novel #Genetic Loci for Nontuberculous #Mycobacterial Pulmonary Disease. I'm glad to see that part of the validation was performed using our previous published data. Enjoy the paper! atsjournals.org/doi/10.1164/...

Do you have a story about how antibiotics have made a difference in your lives or the lives of your loved ones?

Your story and photo could be up in lights at #PiccadillyCircus in London during #WAAW25.

Visit the Fleming Initiative to find out more.

➡️ www.fleminginitiative.org/thank-you-an...

@biorxivpreprint.bsky.social Requirements for development of T-helper1 and T-follicular helper cells from a common precursor @unileiden.bsky.social
www.biorxiv.org/content/10.1...

Rejected…..rejected….

Interferons in health and disease The cytokine messenger proteins known as interferons are central to protective immune responses against infections, but they are also involved in inflammatory and autoimmune diseases. This review maps...

Finally officially out in the latest issue of @cp-cell.bsky.social as a #free #featured #LeadingEdge paper: everything you wanted to know about #InterferonPower! ❤️ @danielboehmer.bsky.social @bostonchildrens.bsky.social @harvardmed.bsky.social www.cell.com/cell/fulltex...

An illustration of a man riding a bike surrounded by wheels and other bike parts, with text: How a Ph.D. is like riding a bike

"For half an hour, I vented everything I had been holding in for months … my supervisor … then calmly offered a line I’ll never forget: 'You are here to learn to ride a bicycle, not to invent a bicycle.' That one sentence landed softly, but it cracked something open." https://scim.ag/4lt1Ru0

Nociceptor neurons suppress alveolar macrophage-induced Siglec-F+ neutrophil-mediated inflammation to protect against pulmonary fibrosis Sensory innervation impacts several lung diseases, but whether it influences pulmonary fibrosis (PF) is unclear. Hiroki et al. report that depletion of TRPV1+ nociceptors leads to worsening of inflamm...

Our latest work on how nerves safeguard lung fibrosis. Congrats to Dr. Hiroki and collaborators. @cp-immunity.bsky.social @kavithascranton.bsky.social @hotchkissbrain.bsky.social @ucalgary.bsky.social @ucalgarymed.bsky.social @libininstitute.bsky.social

www.cell.com/immunity/abs...

Super interesting. Does it work for NTM?

Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.

I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13)
www.nature.com/articles/s41...

Super happy to have attended “The Nontuberculous #Mycobacteria Conference 2025” in Fort Collins! Great talks, outstanding science, and a really cool location. Huge thanks to the organizers. Always a pleasure to reconnect with friends and colleagues! #ntm

What a great day to be at @childrensphila.bsky.social and @pennmedicine.bsky.social

Published today:

www.nejm.org/doi/full/10....

Microbe that infests hospitals can digest medical-grade plastic ― a first Nature - The bacterium Pseudomonas aeruginosa produces an enzyme that breaks down biodegradable plastics.

A strain of bacterium that often causes infections in hospital can break down plastic

https://go.nature.com/3SvsiTC

Cell type–specific efferocytosis determines functional plasticity of alveolar macrophages MPO activates an immunometabolic rheostat to restrict the functional plasticity of macrophages in favor of proresolving properties.

#WeekendRead #NoTimeToDie! Matt, Better &co show @ Science Immunology that efferocytosis of apoptotic neutrophils (not epithelial cells) by alveolar macrophages reprograms their metabolism, boosting glutaminolysis & decreasing ROS, thus favoring repair but facilitating secondary bacterial infections

Totally agree! “The term antibiotic—literally "opposing life", from the Greek roots ἀντι anti, "against" and βίος bios, "life"…..”
I hope to work in this field in the future!

Fahd Al Qureshah, @casanovalab.bsky.social, Qian Zhang et al. show that a common form of dominant human IFNAR1 deficiency impairs IFN-α and -ω but not IFN-β-dependent immunity. rupress.org/jem/article/...

📘In Genes & Immunity collection: rupress.org/jem/collecti...
#HKS2025

Cells are swapping their mitochondria. What does this mean for our health? Researchers are studying why the energy factories are moving between cells and whether the process can be harnessed to treat cancer and other diseases.

New cell cell communication…….mitochondrial exchanges!

www.nature.com/articles/d41...

Ready for the #telethon 2025 scientific convention! #Rimini #italy

Excited to share our last study. Huge congrats to Sarah Monard, Arnaud Métais, @gclugo.bsky.social, @chrisverollet.bsky.social and all colleagues!
We have found a mysterious cell type inside TB lung lesions that seems neuron-like but isn't quite a nerve cell.
Let's dive in👇

shorturl.at/x4Sb5

#interferon history is immunology history! the original cytokine :)

[January 16th, 1980] Scientists at Biogen have successfully produced human interferon, a natural virus fighter, in a laboratory using gene-splicing techniques, potentially making it a more affordable treatment for various viral infections and cancers.

#history #1980s

The man who developed 40 vaccines Microbiologist Maurice Hilleman, PhD’44, and his feathered friends.

"If I had to name a person who has done more for the benefit of human health, with less recognition than anyone else, it would be Maurice Hilleman."—Richard Gallo

Hello @bsky.app 🦋! We’re the European Society of Mycobacteriology (ESM) on a mission to decode the mysteries of mycobacteria 🦠🔬. Stay tuned for exciting research, TB updates, and more. Let’s shape the future of global health together!

Unprecedented asteroid samples contain organic compounds and minerals crucial to life, scientists say | CNN Scientists have detected organic compounds and minerals necessary for life in the samples collected by the OSIRIS-REx mission from a near-Earth asteroid named Bennu.

edition.cnn.com/2025/01/29/s...

Highly multiplexed spatial transcriptomics in bacteria Single-cell decisions made in complex environments underlie many bacterial phenomena. Image-based transcriptomics approaches offer an avenue to study such behaviors, yet these approaches have been hin...

Super cool work! Congrats to the authors.
Spatial bacterial transcriptomics is coming up!

“Highly multiplexed #spatial transcriptomics in #bacteria”

www.science.org/doi/10.1126/...

Great recent work from Sanika Vaidya and Knut Drescher Lab

Mammalian innate immunity recognizes bacterial cell wall peptidoglycan (PG) via TLR2

Turns out multiple bacteria also sense PG from their lysed compatriots as a danger signal to trigger biofilm formation!

www.nature.com/articles/s41...

I have position for research assistant in my Lab at Ospedale San Raffaele in Milan. Please spread the voice and drop me a message if interested

Climate change extinctions Climate change is expected to cause irreversible changes to biodiversity, but predicting those risks remains uncertain. I synthesized 485 studies and more than 5 million projections to produce a quantitative global assessment of climate change ...

Climate change is driving global extinction risks, with 1.6% of species threatened at 1.3°C of warming and risks escalating to 29.7% at 5.4°C, according to a new meta-analysis in Science encompassing more than 30 years of research.

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