A graph of the primary end point
Among patients with atrial fibrillation at high risk for stroke and bleeding, left atrial appendage closure was not noninferior to medical therapy in reducing the risk of stroke, embolism, major bleeding, or death at 3 years. Full CLOSURE-AF trial results: nej.md/3NFE1Ak
#MedSky #CardioSky
Now this is interesting. Ping @damienbarraudmd.bsky.social @load-dependent.eurosky.social
Fresh blog: Six reasons to stop relying on the NPi (neurological pupil index)
👁️ NPi is based on a secret, proprietary formula used by one company
👁️ The neuroICU field was somehow convinced that we're too stupid to understand pupillometry tracings, so we need the NPi...(#1/2) #EMIMCC
1/ 👋 there #neurotwitter #neurosky #neurocritcare, as part of my @neurocritcarej #SoMeAmbassador role, today we will be breaking down the following article: link.springer.com/ar... about consent in research involving #DOC
What are the perceptions of clinicians referring to a novel pediatric #neuropalliative clinic? In the latest issue of #pedneuro, Lin et al explores these perceptions.
Read here: buff.ly/v2nBte7
Map of the USA illustrating 'Emergency Medicaid Spending for Undocumented Immigrants in the US.' States are shaded in colors ranging from light green (1%) to dark blue (2%), representing the emergency Medicaid share of Medicaid spending. JAMA, published online October 9, 2025.
Emergency Medicaid accounts for less than 1% of total #Medicaid spending, even in states with large undocumented populations.
ja.ma/3Yx9hDD
Brainstem lesions in MS are also perivenular, often appearing radially in a "sunray" pattern. Authors include Dr. Gavin Giovannoni and Dr. Dr. Klaus Schmierer pubmed.ncbi.nlm.nih.gov/41447908/
State Medicaid Expansions and Mortality, Revisited:
Medicaid expansions led to declines in all-cause mortality of 6%; HIV-related mortality accounted for 20 percent of the effect.
www.journals.uchicago.edu/doi/abs/10.1...
JAMA infographic: study on valacyclovir for Alzheimer's. Question: Can valacyclovir provide benefit? Conclusion: Not efficacious. Population: 66 women, 54 men, mean age 71.4. Intervention: 120 patients randomized to valacyclovir or placebo. Findings: Valacyclovir worsened cognition vs. placebo.
Valacyclovir was associated with greater cognitive decline and did not improve disease markers in patients with symptomatic #AlzheimerDisease and HSV seropositivity.
ja.ma/4qydeE1
1/ 👋 there #neurotwitter #neurosky #neurocritcare, and Happy Holidays if you celebrate! As part of my @neurocritcarej #SoMeAmbassador role, today we will be breaking down the following article: link.springer.com/ar... about consent in research involving #DoC
new cases/images will be added over time! see something missing or broken? tell me! 🆒
@rkchoi.bsky.social
@zachlondon.bsky.social
@caseyalbin.bsky.social
@birdreader.bsky.social
@cajalbutterfly.bsky.social
@radhikarawat.bsky.social
@thejugglingneuron.bsky.social
@klstenhouse.bsky.social
🚨NEW RELEASE THING🚨
new at: micahetter.me/NeuroPathGal...
"NeuroPath Gallery" - a neuropath case + image gallery for rapid pattern recognition and board review. browse diagnoses, key slide findings, and quiz yourself! 🧠🔬
the most fun you've ever had looking at tissue!😅
HEY EVERYBODY!
i'm back! did you miss me?🙃
i was so busy co-directing the neuro block
@UAZMedTucson
for 1st year med students that I haven't been around as much... but it gave me time to make LOTS of fun stuff!
i'll be gradually releasing, but let's start with...**drumroll**
1/ 👋 there #neurotwitter #neurocritcare, as part of my @neurocritcarej #SoMeAmbassador role, today we will be breaking down the following article:
On September 24, ERAS will open to programs. Which means applicants have only 2 weeks left to decide which programs to signal.
And if you want to know how to allocate your signals in the most effective manner possible, I’ve got something for you:
thesheriffofsodium.com/2025/09/10/t...
1/ Hello #medsky #neurosky #neurocritcare #FOAMEd have another brief case that I wanted to discuss with you and see if maybe you can learn something new or reinforce old knowledge!
🚨NEW RELEASE🚨
🔍Daily neurology connections, anyone?
neuroconnections.me has launched with a free, fun micro-learning puzzle game every day! Still the initial release so let me know if you spot any bugs.🐛
Play and learn here: neuroconnections.me
#Neurology #MedEd
🚨New thing release announcement! 🚨
StrokeBot.me is a free stroke code simulator for trainees! Practice workflows, interventions, disposition calls, and more!
This is just the initial release so bugs are expected and updates ongoing! Enjoy!
#Neurology #MedEd
lithium ion trapped by beta-amyloid and the way to get around it
Could a metal ion supplement that cost pennies per day protect from Alzheimer's disease?
erictopol.substack.com/p/lithium-an...
Bottle of synthroid next to simple anatomical drawing of thyroid gland Bottle of chrome next to brighter illustration of thyroid gland Packet of liotrix next to positively glowing illustration of thyroid gland Bottle of armour thyroid next to cosmically significant illustration of thyroid gland Pubmed headline “An outbreak of thyrotoxicosis caused by the consumption of bovine thyroid gland in ground beef” next extremely bright illustration of thyroid gland overlaying the pillars of creation nebula
1/ Hello #medsky #neurosky #neurocritcare #FOAMEd have a brief case that I wanted discuss with you and see if maybe you can learn something new or reinforce old knowledge!
Image Challenge What is the diagnosis? Upper left: MRI of the brain showing diffuse pachymeningeal enhancement. Lower left: A computed tomographic myelogram. Right: MRI showing protrusion of the cerebellar tonsils into the foramen magnum (tonsillar ectopia), flattening of the pons with effacement of the prepontine cistern, and enlargement of the pituitary gland owing to increased blood flow.
A 50-year-old woman presented to the emergency department with a 10-day history of a throbbing headache that had suddenly started after she had felt a “pop” in her back. The headache worsened with upright positioning and improved with lying flat. 1/4
#MedSky
Case series w/ cumulative total n=110 pts support use of rivastigmine as alternative antidote to physostigmine for anticholinergic delirium. Both oral & transdermal formulations of rivastigmine may expedite recovery #medsky #EMsky #pharmsky #emimcc #FOAMed
👉 link.springer.com/article/10.1...
OpenEvidence is generally very good, but it's occasionally horrifically wrong
One place it falls down a lot is drug allergy (where it's often too conservative)
There are NO absolute contraindications to acetylcysteine for acetaminophen OD
Reported "allergy" = anaphylactoid rxns... (#1/3) #EMIMCC
You had MS even before you had symptoms. This study found increased absenteeism from work 6 years prior to diagnosis. jnnp.bmj.com/content/earl...
This is what we were waiting for. A direct comparison between apixaban and rivaroxaban for the treatment of acute VTE. Apixaban reduces bleeding risk in the first 3 months by >50%!
Practice changing investigator-initiated RCT.
#ISTH2025
A web-comic that says "A Simple Guide to Using AI in Peer Review" with one panel that says "Wrong Way" and the next panel says "Right Way."
Peer review is being transformed by AI, whether we like it or not.
From my own experience, most researchers are using it wrong… and that’s because no one’s talking about it! Let me share some ideas on how to harness its potential to improve scientific publishing.
Herpes Zoster Vaccination and Dementia Occurrence
Herpes zoster vaccination eligibility reduced the probability of new dementia diagnoses, suggesting its potential preventive effect.
https://ja.ma/4lagSB6
What is the prevalence of elevated opening pressure in children with Alexander Disease?
In the current issue of #pedneuro journal, Joung et al. explore this question through analysis of opening pressure, MRI and examination in a cohort of 43 patients.
Read Here: buff.ly/UrvyLjh
