great.

Support my Breakthrough T1D Walk Learn why I'm participating in the Breakthrough T1D Walk and raising funds to help create a world without type 1 diabetes (T1D).

I'm raising money for Breakthrough T1D (new name for JDRF) to change the lives of people with type 1 diabetes.

We appreciate any support. This funding aids T1D research, which is even more important now with the uncertainty surrounding traditional research funding mechanisms.

p.bt1d.org/7ujvl

Wow. Just to make this clear to people who aren't familiar - this means that if 100 scientists submit R01s, maybe 50 will get discussed and about 2-3 will get funded at that payline. Correct me if my math is off.

Indeed. Hard to get cited if you don't get a grant.

Forbidden Lychee

Thanks @worthamlab.bsky.social !

Worried Northwestern lab directors describe ‘bleak’ atmosphere in wake of Trump research funding freeze The Trump administration’s freezing of $790 million in federal research funding for Northwestern University has left concerned lab directors without key grants and forced the university to spend mi…

I helped explain to the Chicago Tribune the enourmous and irrational damage the NIH funding freeze is causing at Northwestern. “You’re at risk of losing an entire next generation of scientists" "it’s terrifying; it’s completely senseless." www.chicagotribune.com/2025/06/07/w...

Actin remodeling in beta cells adds new layers of upstream regulation - Congrats! @ronnyhelman.bsky.social

NIH Research Funding at Risk—Take Action Now! - ASCB Along with supporting important scientific discoveries, federally funded scientific research has significant impact on state and local economies. It is estimated that, on average, every $1 of National...

Science is under attack. Proposed 40% NIH cut threatens jobs, research, and medical progress. Call your reps, governor, and mayor now—urge them to stand up for science.

www.ascb.org/science-poli...

Imminence - Heaven Shall Burn (Live at Ystads Teater) YouTube video by Imminence

take a metal break www.youtube.com/watch?v=e2ms...

I have one on my wall. You can only hunt them on April 31st.

Paradoxically, both GIPR agonism and antagonism potentiate weight loss when paired with GLP-1R agonism. Two new studies in @natmetabolism.nature.com decode the different neural mechanisms employed by each strategy.

Check out the #News&Views by @adriaenssenslab.bsky.social here.

Improving Performance, Accountability and Responsiveness in the Civil Service The Office of Personnel Management (OPM) is proposing a rule to increase career employee accountability. Agency supervisors report great difficulty removing employees for poor performance or misconduc...

The notice and COMMENT PERIOD OPENED TODAY AND CLOSES MAY 23.

Anyone who would like to register an objection or comment should go to this page and click on the green “public comment” button at the top:

www.federalregister.gov/documents/20...

6/n

She could still study Cancer though...

My condolences on that burn

NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.

NIH is the best investment there is.

www.forbes.com/sites/michae...

Just posting this starter pack for #PancSky again as I have added more people - let me know any other islet/pancreas scientists I've missed! go.bsky.app/3wdSpdi

Hey #PancSky and #islet people, we're hosting the 2025 Midwest Islet Club in Indianapolis May 7-8. Most of the talks are from students/postdocs. Help spread the word about abstract submission and registration! medicine.iu.edu/research-cen...

Breaking: FDA's March meeting to select flu shot strains for 2025-2026 season has been canceled per email sent to committee members, a VRBPAC member told me. drug companies need about 6 months leeway to make shots in time for fall vax campaigns. #healthpolicy

Join us! Science Homecoming helps scientists reconnect with communities by writing about the importance of science funding in their hometown newspapers. We’ve mapped every small newspaper in the U.S. and provide resources to get you started. Help science get back home 🧪🔬🧬 🏠

sciencehomecoming.com

NIH funding freeze stalls applications on $1.5 billion in medical research funds The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.

The National Institutes of Health had to stop considering new grant applications, delaying funding for research into diseases ranging from heart disease and cancer to Alzheimer's and allergies.

5 Calls Spend 5 minutes. Make 5 calls. Make your voice heard.

Ok scientists & those who love science 🧪: here is another exhortation. Call Congress TODAY about the freeze on NIH Council Meetings and Study Sections. Emphasize that this means NO new grants are being funded & labs will soon start to shut down and fire employees. Phone numbers are at:
5calls.org

I've been developing a semantic search tool that covers not just bioRxiv and medRxiv, but the entire PubMed database. This means you can search across a massive collection of biomedical research using keywords, questions, hypotheses, or even full abstracts. Try it out: mssearch.xyz

‘Wrecking ball’: RFK Jr. moves to fire thousands of health agency employees Supervisors deliver bad news across NIH, CDC

www.science.org/content/arti...

I don't think IIDP is on Bluesky yet, so just reposting.
iidp.coh.org/funding
Applications Due: February 14, 2025.
#islet #PancSky

Reminder: You can always submit a grant late and include a cover letter saying why. NIH receipt and referral may take it. Or not. If you end up missing deadline because of these Commons access issues, there is this potential save move.

good to know

New preprint from the lab! 🚨

🧫 New galactose #CRISPR screening strategy
🎯 481 genes required for #OXPHOS
⚙️ #FAM136A in IMS proteostasis
👂Mito defects in #Menieres disease

by @marcellharhai.bsky.social @fbm-unil.bsky.social

A short thread 1/5

www.biorxiv.org/content/10.1...

"Of Wolf and Man" by Metallica x "Fifflas" by C418

Will be very interesting to see how molecular biology changes in the next decade with these types of advances.