Three Botrytis/Eudicot papers accepted.
A reevaluation point on a question about generalism started with @katherinedenby.bsky.social 's sabbatical 24 years ago. Continued by a broad team of undergrads to post-docs including @annajomu.bsky.social @ccaseys.bsky.social and more not on bsky.
Postdoctoral Scholar position in the Coaker group University of California, Davis We are seeking a Postdoctoral Scholar to join our research program focused on immune receptor engineering and spatial analyses of plant pathogens interactions using computational and imaging approaches. The position will involve integration of molecular, imaging, and computational approaches. Relevant publications from the laboratory include Nature Plants (2025, PMID: 40721669), Proceedings of the National Academy of Sciences (2024, PMID: 38814867), and Cell Reports (2023, PMID: 37342910). https://www.coakerlab.org/ Qualifications: • Ph.D. in plant biology, molecular biology, genetics, computational biology, or a related field • Strong background in genomics and/or computational biology • First author publications in peer-reviewed journals • Ability to work both independently and collaboratively in a multidisciplinary environment • Experience in plant innate immunity is preferred Application Instructions: The position is initially available for two years, with the possibility of extension based on performance and funding. Salary is based on the University of California postdoctoral salary scale (https://www.ucop.edu/academic-personnel-programs/_files/2025-26/represented-oct-2025-scales/t23.pdf). The salary range for this position is $69,073-$82,836 US Dollars/year. Review of applications will begin June 1, 2026 and will continue until the position is filled. Please submit a CV, a brief statement of research interests (~1 page), and contact information for three references to glcoaker@ucdavis.edu. The research statement should describe your previous work, how your expertise aligns with ongoing research in the lab, and potential future research directions.
We are hiring! We’re excited to recruit a postdoc to our lab at UC Davis to work on plant immune engineering and single-cell analyses of plant pathogen interactions. Apply by June 1. Please repost. www.coakerlab.org/postdoctoral...
This is WILD
(& microbes rock 🎸)
“These findings […] revealing a protein-templated mechanism for sequence-specific DNA synthesis.”
Take that, central dogma! 🧪
“Protein-templated synthesis of dinucleotide repeat DNA by an antiphage reverse transcriptase”
www.science.org/doi/10.1126/...
Sharing the latest preprint from our lab where we identify pervasive presence of Genomic Islands (GIs) in diverse giant viruses and characterize their functions and origins - leveraging cultured isolate genomes and long-read sequenced giant virus genomes.
www.biorxiv.org/content/10.6...
Model of resistance transition in Brassicaceae.
The non-NLR gene JAX1 drives potexvirus nonhost resistance across the Brassicaceae
Suzuki et al.
nph.onlinelibrary.wiley.com/doi/10.1111/...
🔈Paper out! We turned the most fascinating phage host-switch mechanism, diversity-generating retroelements, into a programmable mutagenesis tool, DGRec. You can perform targeted hypermutation of any 50-200bp sequence directly in vivo in E. coli www.nature.com/articles/s41...
#joboffer #Germany
plz spread it
I'm hiring a Junior leader (E13; 100% for 3-5 y) to start own independence w/ focus on #CryoEM SPA or ET
Ideally 1-2y postdoc experience
Plz get in touch, if you are interested in #Structural biology & #MicroBiochem
@sfb1381.bsky.social @vaam-microbes.bsky.social
Plasmidsaurus RNA-Seq is now processed in Cologne for our European customers!
Ship at ambient temperature with SEQguard Dino Preserve 🦖
• 3-day turnaround
• $50/sample (academia), $80 (industry)
• Gene expression analysis
• Up to ~10M unique transcript 3’ end reads per sample
• Interactive results
Over two billion years, a fierce battle has raged between bacteria and the viruses that infect them. The resulting evolution has shaped the way our bodies fight disease today. @vcallier.bsky.social reports: www.quantamagazine.org/the-ancient-...
We are happy to celebrate @mpcontreras.bsky.social winning the @biochemsoc.bsky.social 2027 Early Career Research Award!
Mauricio joined TSL as a predoc with @kamounlab.bsky.social, where he did PhD and postdoc before starting his group at @zmbp-tuebingen.bsky.social
Congrats Mau!
New pre-print from the lab! We show that the subtilase SBT12a is essential for symbiosome stabilization in Medicago. Using HUNTER proteomics, we even got some of its substrates. Have a look.
www.biorxiv.org/content/10.6...
Transition metal-triggered immunity via an Arabidopsis NLR pair www.biorxiv.org/content/10.64898/2026.04...
Great to see this paper in its final published form!
www.pnas.org/doi/10.1073/...
Our colleague needs your help keeping a 1,200-year dataset alive!
If you have botanical expertise or are based near Arashiyama, Kyoto — DM her or email tuna@ourworldindata.org.
🚨 Why can’t mammals regenerate limbs like frog tadpoles or salamanders?
In our new paper in @science.org , we show that species-specific oxygen sensing acts as a gatekeeper for initiating limb regeneration 🐭🐸
🔗 www.science.org/doi/10.1126/... #EvoDevo
Deep-Plant: a supervised foundation model for plant regulatory genomics www.biorxiv.org/content/10.64898/2026.04...
Check out our new manuscript, in collab with Efrat Sheffer, Guy Dovrat and Amir Erez, where we looked at shotgun metagenomes of wild legume nodules, providing an unbiased view of the taxonomic genomic content of legume nodules, and how these relate to plant performance.
PostDoc position available!
(links in post below)
Feel free to share!
Cucumber genetics got a 172,000-piece upgrade. That's how many large DNA rearrangements BTI scientists catalogued by combining 39 cucumber genomes into one mega-map. Now breeders have a powerful tool to work with.
https://cstu.io/2dae4c
Preprint alert 🚨 (1/10) 🧵
𝘈𝘶𝘵𝘰𝘱𝘩𝘢𝘨𝘺 𝘪𝘴 𝘢 𝘱𝘢𝘳𝘢𝘥𝘰𝘹 𝘪𝘯 𝘱𝘭𝘢𝘯𝘵 𝘪𝘮𝘮𝘶𝘯𝘪𝘵𝘺:
It can promote resistance, susceptibility, or restrict cell death 🤯
So what is its actual role?
We show it acts as a spatial organizer of immunity across cell types 🌱🦠 #proteostasis
www.biorxiv.org/content/10.6...
Seriously cool work from a cross-national team. Textual and image analysis of a Nahua botanical codex to understand how indigenous peoples' knowledge of plants was structured & maintained. Including a website containing images, texts, & translations (danchitwood.github.io/DeLaCruzBadi...)
A fascinating read! Spain’s infrastructure operator jump-started high-speed competition, and passenger numbers have increased by up to 68% since 2019.
Out now in @newphyt.bsky.social with @joannarifkin.bsky.social, @jotlovell.bsky.social, @spicybotrytis.bsky.social & more! Our high-quality pennycress pangenome is a striking example of genome architecture shaping different kinds of genomic variation, including some surprising centromeric movement
New paper from the Stern and Gronenborn labs on structure and evolution of aphid bicycle effector proteins.
We show how alphafold can generate accurate predictions for these rapidly evolving proteins and that these proteins are diverse in every possible way.
www.biorxiv.org/content/10.6...
The PhageExpressionAtlas just made it to bioRxiv. Visually explore the transcriptomes of phage-host interactions or harness the database for analysis across infections! Please leave feedback, which functionalities/data you find missing.
Preprint:
www.biorxiv.org/content/10.6...
#phagesky #microsky
New #preprint 😍‼️ led by 2 incredible postdocs @ninizhani.bsky.social & Ranj Papareddy: transforming #UFMylation from a local ribosome rescue pathway to systems level regulator of mRNA splicing www.biorxiv.org/content/10.6... A short 🧵
A long, skinny map titled: "Life and Travels of the European Eel" with a subtitle reading: "From the Eel's Perspective." A label at the bottom of the map reads: "Begin Here." The map top half of the map is an mirror copy of the bottom half. I will put the full text of the column in the alt text in an image in the next post in the thread. The map goes from the bottom of the page up, starting in the Sargasso Sea. An set of arrows show the eels paths to shore, then up a river and into a marshland. The arrows continue up the page to show the eel leaving the marshland and heading back downstream, and out to sea. The land is green and verdant at the bottom of the map, because the eels migrate upstream in the spring. The land is brown and dry at the top of the map, because eels migrate downstream in the autumn. A column of text on the side tells about the eels' journeys and changes. It is more text than I can relate in the space allowed here. Each paragraph has an arrow pointing up to the next one, and they are designed to be read from the bottom of the page going upwards.
Several years ago, on a whim, I started drawing a map of an eel's life travels as seen by the eel.
I figured an eel thinks about its life as a linear journey, rather than a there-and-back again adventure. So I wanted to do a map to reflect this.
This morning, on another whim, I finished the map!
What if plant immunity doesn’t stop bacteria from arriving - but from staying?
Excited to share our new Dangl Lab paper (doi.org/10.1073/pnas.2535583123), asking a fundamental co-evolutionary question: which flagellar function is targeted by plant immunity?
#Coevolution #Plant-Microbiome #PNAS
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