Bhattacharya killing one of the most promising technologies in a generation for improving health, treating disease, & preventing mass death from pandemics was unforgivable; this will be his legacy
I was interviewed about his lies about mRNA vaccines here: www.bioxconomy.com/modalities/e...
Monoclonal antibody cocktails show promise in combating RSV, reducing viral titers in studies. A new frontier in respiratory infection prevention.
#RSV #AntibodyTherapy
Read my full article below:
www.bioxconomy.com/modalities/s...
Peptides market to explode following success of GLP-1s.
Experts predict a value of almost $300 billion by 2033, with the US dominating more than 60% of the market.
#news #invest #glps
Read my full article below:
www.bioxconomy.com/modalities/p...
‘Quieting craving itself’: GLP-1s reduce risk of substance addiction in US veterans
In a landmark observational study of over 600,000 US veterans with type-2 diabetes, #GLPs reduced addiction rates and adverse outcomes.
Read my full article below:
#news #science
www.bioxconomy.com/modalities/q...
CDMO Neuland Laboratories announced that it will open its peptide facility in summer 2026. The site, which will produce glucagon-like peptide-1 (GLP-1s), is just 40 miles from Hyderabad, India.
Read my full article below:
#peptide #GLP
www.bioxconomy.com/modalities/n...
Researchers from Columbia University were able to up-regulate a cardio-protective peptide in animal models using self-amplifying RNA. The peptide preserves cardiac function after a heart attack.
Read my full article below:
#heart #peptide #heartattack
www.bioxconomy.com/modalities/h...
The FDA asked pharma company UniQure for a “double-blind, sham surgery-controlled study” of its mutation-rescuing Huntington’s disease therapy. Study leader Edward Wild has expressed ethical concerns.
Read my full article below:
#FDA #Huntington #genetherapy
www.bioxconomy.com/modalities/f...
What happens to gene therapies that are proven to save lives, but that are not commercially viable? Academic institutions are picking up the slack in a for-profit industry.
Read my full article below:
#genetherapy #access #nonprofit
www.bioprocessintl.com/upstream-dow...
Pfizer recently announced promising Phase II clinical trial results (NCT05995964) for its trispecific antibody product, tilrekimig, targeting eczema and other inflammatory conditions.
Read my full article below:
#eczema #antibody #pfizer
www.bioxconomy.com/modalities/p...
For years, mental health professionals have observed an association between poor diet and severe depression. A new food-derived peptide could take advantage of this gut-brain connection.
Read my full article below:
#depression #diet #mentalhealth
www.bioxconomy.com/modalities/y...
Pancreatic cancer is a devastating disease, with high mortality rates due to late symptom onset. Scientists speculate immune evasion is the reason for its late discovery. A new mRNA therapy from UPenn offers a solution.
Read my full article here:
#cancer #mRNA
www.bioxconomy.com/modalities/c...
Up to 30% of women with endometriosis experience fertility problems, and current cytokine-based treatments come with risks. A new mRNA therapy out of John Hopkins has shown promising preclinical results.
Read my full article below:
#endometriosis #fertility #mRNA
www.bioxconomy.com/modalities/i...
When Jay Bhattacharya & RFK Jr canceled federal funding for mRNA vaccine R&D, they wrote 2 of the most putrid OpEds I’ve ever seen—full of vile, pathetic lies
I was interviewed about those OpEds here: www.bioxconomy.com/modalities/e...
One of the most damaging decisions in public health history
Here’s what I said when Jay Bhattacharya and RFK Jr canceled federal funding for mRNA vaccine R&D and each of them wrote pathetic OpEds justifying their dangerous act
www.bioxconomy.com/modalities/e...
He made a compelling case for merging the stable antagonistic nature of antibodies with the flexibility, small size, and agonistic properties of peptides. His team is already hard at work applying these ideas to areas like obesity and autoimmune conditions.
So when I first learned about antibody-peptide conjugates (APCs), I was confused. Isn't that a bit redundant?
Leave it to Kerry Blanchard at the Shanghai- and Boston-based Perpetual Medicines to disabuse me of that notion.
Medium shot of Kerry Blanchard at TIDES Asia in 2025, photo by Soren Hough
For many, and certainly for me, antibody and peptide conjugation often serves a similar purpose. Our own reporting has covered how these molecules are typically linked to LNPs, drugs, or oligos to help bring them to specific targets.
Ethically problematic Hep B vaccine trial in Guinea-Bissau (often termed "RFK Jr.'s Tuskegee experiment because it is HHS/US taxpayer funded) put on full hold by the Danish university of the study's principal investigators. Now awaiting ethics review by the WHO.
health policy 🛟😷 medsky sociology 🧭
"A controversial proposed clinical trial in Guinea-Bissau has been suspended, according to Ole Skøtt, dean of the faculty of health sciences at the University of Southern Denmark (SDU). "
www.bioxconomy.com/modalities/g...
Guinea-Bissau trial 'on full hold’ at University of Southern Denmark
SDU dean Ole Skøtt said the trial will be assessed by ethics experts from the World Health Organization.
www.bioxconomy.com/modalities/g...
Not surprising that Tuskegee Experiment Part Deux has even more impropriety and issues than was immediately obvious. This cannot go forward.
Good point
I believe the proposed trial in Guinea-Bissau would be deeply unethical (funded by RFK Jr, the Danish researchers would knowingly withhold the hep B birth dose from half of newborns, consigning many of them to sickness & early death)
But let's consider what the Danes argue
Short 🧵
Hey, looks like you swiped our whole article without asking and reposted it without formatting or attribution. That's not cool! I'd ask that you take it down, or replace it with just the first paragraph and a link to our site for the rest.
Hey, looks like you swiped our whole article without asking and reposted it without formatting, relevant links, or attribution. That's not cool! I'd ask that you take it down, or replace it with just the first paragraph and a link to our site for the rest.
Thanks, Gavin! It's been quite the saga. One wonders if at this point the delays will time them out of their launch window.
The RFK Jr-funded trial in newborn babies that Danish researchers want to conduct in Guinea-Bissau becomes ethically murkier by the day
Here's a valuable new piece by @sorenhough.bsky.social & Josh Abbott; they've been doing stellar reporting on a trial that's been called "the new Tuskegee"
