Increased phosphorylated tau (pTau-181) is associated with neurological post-acute sequelae of coronavirus disease in essential workers: a prospective cohort study before and after COVID-19 onset N-PASC with symptoms consistent with central damage were associated with increased pTau-181 levels. Increases in pTau-181 were associated with increased risk of changes to amyloid biomarkers consisten...

Study of neuro LongCovid patients found pTau-181 (marker of Alzheimer's/brain injury) increased by 59% after COVID.

Levels increased more AFTER 1.5 years from infection (only 15% increased in the before-1.5 year time period).

Via Hannah Davis

#LongCovid

www.thelancet.com/journals/ebi...

Gefeliciteerd Kirsten 💐

Zet hem op Kirsten. Het gaat top 💪🏼🏃‍♀️

Long COVID Linked to Arrhythmias and Coronary Disease Long COVID raises cardiovascular risk in men and women, even without hospitalization. Women are at higher risk for heart failure and peripheral vascular disease, highlighting the need for systematic f...

Technology Networks: "Long COVID Linked to Arrhythmias and Coronary Disease"

'Study finds long COVID increases risk of cardiovascular disease, including arrhythmias and coronary disease.'

www.technologynetworks.com/immunology/n...

🩺 This is a great treatment guide.

#Long-covid

🩺 New study: COVID worsens the ability of red blood cells (RBCs) to generate energy for themselves.

In women, RBCs have a harder time releasing oxygen to the body's tissues; in men, RBCs have a harder time repairing and defending themselves.

Via Hannah Davis

#SARS-COV-2 #COVID #Long-covid

I'm so sorry for your loss 💔

Beterschap Kirsten. Neem de tijd om op te knappen.

*niet

🥵 net gehaald binnen de tijd. 😅

Bone Mineral Density, Bone Biomarkers, and Joints in Acute, Post, and Long COVID-19: A Systematic Review SARS-CoV-2 is highly transmissible and affects the respiratory system. People with COVID-19 are at higher risk of physical and mental health conditions, which could impact bone health. The aim of this review was to explore the effects of COVID-19 on ...

🩺 Meta-analysis finds bone mineral density decreases after COVID infection. - The most significant reduction happens a year after infection.

#covid #SARS-COV-2

pmc.ncbi.nlm.nih.gov/articles/PMC...

🩺 Virus-induced endothelial senescence as a cause and driving factor for ME/CFS and long COVID: mediated by a dysfunctional immune system.

#longcovid #MECFS

www.nature.com/articles/s41...

"We believe that internal tremors [in #LongCovid] represent... dysautonomia & small fiber neuropathy... caused by hypovolemia, cerebral hypoperfusion, hyperadrenergic state, mast cell hyperactivation, & neuropathic processes affecting small nerve fibers."

www.mdpi.com/2035-8377/17...

Fijne Kerstdagen Kirsten.
Dank je wel voor de update op deze 1e Kerstdag.

Researchers studied 95 people and found that 73% of long COVID patients relied mostly on carbs for energy at rest, compared to 20% of controls.

This inefficient energy use was strongly linked to fatigue and post-exertional malaise.

www.researchsquare.com/article/rs-8...

Ja ik. Elke dag je berichten op Bluesky en je nieuwsbrief in het weekend. Heel blij met jouw berichtgeving. Elke dag tenenkrommend, maar zo blijf ik goed geïnformeerd vanuit betrouwbare bron en dat is heel belangrijk. Dank je voor je tomeloze inzet 🙏🏼

🩺 #Long-covid #PAIS #lidocain

Hormone replacement therapy (HRT) is not dangerous. Timing and formulation are critical components of benefit vs. harm. I’m glad to see the FDA warnings removed from HRT.

Thanks @bloomberg.com for covering this important topic: www.bloomberg.com/news/videos/...

How persistent pathogens could accelerate the aging process | Amy Proal | TEDxBoston YouTube video by TEDx Talks

TEDx Talks: "How persistent pathogens could accelerate the aging process by Amy Proal"

'..gut tissue collected from a person with long COVID almost 2 years after..here's the thing, these chronic pathogens are the closest thing there are to hackers of the human body"

www.youtube.com/watch?v=XMcV...

Strange microscopic structures found in Long COVID blood Scientists have discovered strange microscopic structures in the blood of people with Long COVID—clusters of tiny microclots tangled together with sticky immune webs known as neutrophil extracellular ...

🩺 Strange microscopic structures found in Long covid blood.
#LongCovid #microclots

Meet the COVID-19 Researcher Whose Studies Help Shape Patient Care Akiko Iwasaki, PhD, a Yale School of Medicine immunologist, is working toward a greater understanding of the SARS-CoV-2 virus and COVID-19 from many different angles.

March 2021, Yale Medicine: 'Meet the COVID-19 Researcher Whose Studies Help Shape Patient Care'

'...millions of people around the world who will continue to suffer from long and debilitating symptoms. We need better diagnosis & treatment for long COVID'

www.yalemedicine.org/news/covid-1...

Gut infection and dysbiosis are hallmarks of severe SARS-CoV-2 variants - npj Viruses npj Viruses - Gut infection and dysbiosis are hallmarks of severe SARS-CoV-2 variants

Cøvid related gut dysbiosis ...

Most definitely not your friend ☠️

www.nature.com/articles/s44...

Tricuspid valve: Once disregarded, now acknowledged The Tricuspid Valve (TV) has been a subject of increasing clinical and research interest over the last century due to recognition of the importance of…

🩺 Tricuspid valve; once disregarded, now acknowledged.
Different Tricuspid valve leaflets in various echo views.
#tricuspidvalve #myocard

SARS-CoV-2 infection heightens the risk of developing HPV-related carcinoma in situ and cancer - PubMed SARS-CoV-2 infection is associated with elevated risks of HPV-related carcinoma in situ and cancer, irrespective of age or race. The findings underscore the importance of understanding the interplay b...

🩺 SARS-CoV-2 infection heightens the risk of developing HPV-related carcinoma in situ and cancer.
#HPV #SARS-COV2 #cancer

pubmed.ncbi.nlm.nih.gov/40813533/

Hidden Heart Damage: How COVID Continues Haunting Millions Five million people worldwide may be walking around with cardiac long COVID, their hearts silently struggling months or years after their initial

ScienceBlog: 'Hidden Heart Damage: How COVID Continues Haunting Millions'

'Five million people worldwide may be walking around with cardiac long COVID, their hearts silently struggling months or years after their initial infection cleared'

scienceblog.com/hidden-heart...

Haptoglobin phenotypes and structural variants associate with post-exertional malaise and cognitive dysfunction in myalgic encephalomyelitis - Journal of Translational Medicine Background Myalgic encephalomyelitis (ME) is a chronic, multisystem illness characterized by post-exertional malaise (PEM) and cognitive dysfunction, yet the molecular mechanisms driving these hallmar...

🩺 New study on PEM

After a mild stress challenge, people with ME had a sharp drop in haptoglobin (Hp), a blood protein that protects the body from damage when red blood cells break down.

Low Hp correlated with worse #PEM and cognition.

translational-medicine.biomedcentral.com/articles/10....

Thank you!

📌 Thank you for sharing

Changes in the pulmonary surfactant in patients with mild to moderate COVID-19 Introduction Changes in the pulmonary surfactant have been seen in severe COVID-19, but data on mild to moderate COVID-19 is scarce. The aim of this study was to explore the protein and phospholipid p...

🩺 New study finds lasting damage to lung surfactant in mild to moderate COVID19.

Even months later, key phospholipids remain disrupted.

Persistent impairment of respiratory function.

#SARS-CoV-2 #Covid-19

journals.plos.org/plosone/arti...

📌 Thank you for sharing