Excited to share a new review by @kocherlab.bsky.social and me:
Nature-inspired neuroscience
We discuss diverse sensory systems and behaviors across the animal kingdom and argue for their integration into neuroscience. New tools in diverse systems are making this possible ✨
tinyurl.com/y5y9du27
Interview with @braininspired.bsky.social for my book "The Brain, In Theory":
www.youtube.com/watch?v=T3zE...
The supply of blood to brain tissue is thought to depend on the overall neural activity in that tissue, and this dependence is thought to differ across brain regions and across brain states. However, studies supporting these views have measured neural activity as a bulk quantity and related it to blood supply following disparate events in different regions. Here we measure fluctuations in neuronal activity and blood volume across the mouse brain, and find that their relationship is consistent across brain states and brain regions but differs in two opposing brainwide neural populations. Functional ultrasound imaging (fUSI) revealed that whisking, a marker of arousal, is associated with brainwide fluctuations in blood volume. Simultaneous fUSI and Neuropixels recordings showed that neurons that increase activity with whisking have distinct haemodynamic response functions compared with those that decrease activity. Their summed contributions predicted blood volume across states.Brainwide Neuropixels recordings revealed that these opposing populations coexist in the entire brain. Their differing contributions to blood volume largely explain the apparent differences in blood volume fluctuations across regions. The mouse brain thus contains two neural populations with opposite relations to brain state and distinct relationships to blood supply, which together account for brainwide fluctuations in blood volume.
How does blood flow relate to brain activity? We discovered that it reflects two neural populations affected oppositely by arousal. Together, they explain neurovascular coupling in all brain regions and brain states!
Out today in Nature: rdcu.be/fdC2A
@uclbrainscience.bsky.social
Want to explore connectivity & projection patterns yourself, like we do here? We released brain_street_view to let you pick any injection site in the Allen Connectivity Atlas and visualize where it projects in your favorite region of interest: github.com/Julie-Fabre/brain_street_view
⚠️ Postdoc Opportunity in System Neuroscience at the Paris Brain Institute ⚠️
Feel passionate about neuroscience and sleep 🧠? Want to learn cutting-edge techniques 🔬 to answer exciting basic science questions? Want to work in a multidisciplinary environment at the heart of Paris 🏨?
Come join us !
New paper in Nature, @nature.com (go.nature.com/4c4OjCj) : how do social roles emerge in groups of near-identical individuals ? we find that they are neither predetermined nor fixed.
Join us in Paris Sleep Day, 19th of May, a free one-day symposium dedicated to connect early-career researchers working on sleep in Paris and build a long-term local support network.
Registration and submission details are available here: docs.google.com/forms/d/e/1F...
Hope to see you there! ✨
Merci a Sarah-Lou Lepers du podcast Tangram de @psl-univ.bsky.social d'etre venue nous interroger au @mnhn.fr avec @anthony-herrel.bsky.social pour parler de respiration et du sommeil des reptiles🦎 !!
Lien vers l'episode: podcast.ausha.co/tangram/ce-q...
Cosyne invited me to give a long tutorial (4 hours!) on methods to quantify differences high-d neural recordings across animals, brain regions, deep neural nets, etc.
The recording is up on youtube. I hope it inspires more research on this fundamental topic!
www.youtube.com/watch?v=n44x...
Please circulate widely!
Open positions at the Vision Lab, Centre for Neuroscience, Indian Institute of Science (IISc)
sites.google.com/site/visionl...
How to Apply:
forms.gle/vWa1PwUrcpWf...
Deadline : March 31 2026
Aging may feel gradual… but what if it’s not?
In our recent paper, we tracked fish continuously from puberty until death.
This gave us a unique view of how aging unfolds across the adult lifespan.
🧵
1/4 When rules change, dopamine (DA) changes what it calls an “action”.
New bioRxiv version: “Dopamine tracks adaptive learning of action representations”.
www.biorxiv.org/content/10.1...
This project brought together Maxime Come’s PhD work and Arnaud Lespart’s postdoctoral work in our lab.
Institut Jacques Monod Seminar
Friday, Feb 27
Institut Jacques Monod
Gautam Dey @gautamdey.bsky.social (EMBL, Heidelberg) Evolution and diversity of mitosis
Exciting evolutionary cell biology: bridging genomics, experimental evolution, and stunning imaging across diverse protozoans
buff.ly/uCSfjgQ
You have until March 3rd to apply for the Cajal summer school on Quantitative Approaches to Behavior and VR at Champalimaud! Come surf and track animals with us 🏄🪰🐟🚶
cajal-training.org/on-site/quan...
Et si la lumière permettait d’éteindre la douleur ? Une nouvelle étude montre qu'une brève exposition aux UV diminue la sensibilité des souris pendant plusieurs heures. Une piste inattendue pour soulager la douleur animale.
I have a different take
Based on personal interactions, my take on these scientists is that they were weaselly arrogant assholes but can we shift the blame to institutions that enabled all this? And not just Ivys or MIT - e.g. Mt Sinai interacted with him/his staff for years AFTER his conviction
Build hands-on skills in optical & electrophysiological methods at the TENSS 2026 course & advance your skills in modern systems #neuroscience
🔗 Apply by 1 Mar: https://ibro.org/training-opportunity/perc4_romania/
#IBROinAsiaPacific #IBROinUSCanada #IBROinAfrica #IBROinLatAm #IBROinEurope #training
Postdoc job alert at Institut Jacques Monod in Paris! Interested in fundamental membrane trafficking? We seek a postdoc to study collagen secretion as a model for core principles of how cells and their environment build each other. emploi.cnrs.fr/Offres/CDD/U...
The fact that Epstein had ties to the scientific community is not news, but the enormous cache of documents released by the DOJ last week was still startling. It showed just how deeply Epstein was involved—how many were in his orbit, and how deeply involved he was with some research.
My reporting:
A crucial point to keep in mind when considering automation: work is not about production and money, it's about care. Or at least it should be, if we take some distance with managerial brainwashing.
1/4
Awesome! Thanks
Academics vying for a spot in Epstein‘s world. There are so many. I feel the need to make a thread, so I don’t keep confusing them. 1/
New PhD alert! We'll be applying animal welfare ideas to look at how stress affects bees, looking at the effect on bee brains with @lenariab.bsky.social, and working with @sensibee.bsky.social developing new monitoring methods.
Please spread the word! #bees #PhD 🧪
www.findaphd.com/phds/project...
#Geometric principles of #dendritic integration of excitation and inhibition in #cortical #neurons | Science Advances www.science.org/doi/10.1126/...
Our recent work on the prefrontal cortex was featured in @nautil.us.
Check out the article here: nautil.us/the-brain-mi...
@pierrelemerre.bsky.social @carlenlab.bsky.social @ki.se
If you are a PhD student or post-doc who wants to learn everything about #electrophysiology or #imaging, consider registering to the Paris Spring school in optical imaging and electrophysiology, that will take place in the center of Paris 11-23 May 2026. Application deadline Feb 2nd
parisneuro.ovh
An excellent, bone-chilling story about a cadre of online racists who stole genetic data from studies on children so they could make specious arguments for the innate inferiority of non-white people, it's embrace by Elon Musk/twitter & how the Trump administration might make it easier to do again.
