Most bacteria remain uncultured with vast microbial ‘dark matter’ awaiting discovery.. to address this am excited to share EDEN - an enhanced domestication method to grow uncultured bacteria & new diversity. Using EDEN we isolate a new species active against MDR pathogens..
doi.org/10.1093/isme...
Posts by Merve Tepe, PhD
Priest will come to give me last rites and take my final confession and with my dying breath I will declare that vaccines prevent disease, not infection
“This Year in Public Health” at #ESCMIDGlobal2026:
⚔️ War accelerates AMR
🏥 Strained systems + disrupted surveillance
🦠 Resistance spreads across care networks
A hidden consequence of conflict—and a growing threat.
“This Year in Public Health” at #ESCMIDGlobal2026:
💊 Cutting unnecessary antibiotics isn’t just good medicine—it saves money
📉 Stewardship programs reduce overprescribing
💰 Lower drug costs, fewer adverse events, less AMR burden
Better prescribing = better outcomes + real savings
For those that don't know (included me!), Gremubamab binds specifically to the Pseudomonas aeruginosa PcrV protein and the Psl exopolysaccharide.
Both are virulence factors used for adhesion and biofilm stability.
Thanks @microsoft-copilot.bsky.social !
#ESCMIDGlobal2026 #IDSky #ClinMicro
Promotional graphic for AMR Innovation Exchange, a free-for-members virtual webinar series on antimicrobial resistance.
Join our AMR Innovation Exchange webinar, this time 'Clinical Trial Oversight in Bangladesh: A Regulatory Perspective'
📅 20 April 12:00 BST
🎤 Dr Sabrina Yesmin
Register now: https://microb.io/4tU5RIJ
#KOAMR #KnockingOutAMR #RegulatoryAffairs #Webinar
JAMA study: Rapid antimicrobial susceptibility testing (AST) vs. standard AST for bloodstream infections. Conclusion: rapid AST wasn't superior. Population: 486 males, 364 females, median age 72. Intervention: text@1, text@2. Findings: alive at 30 days, similar rates.
Among patients with #GramNegativeBacteremia, rapid #AntimicrobialSusceptibilityTesting did not improve 30-day clinical outcomes compared with standard testing, despite providing faster guidance for antibiotic escalation or deescalation.
#ESCMIDGlobal2026
ja.ma/4sF52lG
🔈Paper out! We turned the most fascinating phage host-switch mechanism, diversity-generating retroelements, into a programmable mutagenesis tool, DGRec. You can perform targeted hypermutation of any 50-200bp sequence directly in vivo in E. coli www.nature.com/articles/s41...
🚨 Don’t miss out!
On What Do Patients and Publics Consider Ethical? Insights from Deliberative Workshops on Pathogen Genomics ⚖️
📅 Thursday 23rd April
💻 ECR Presentation: Wastewater insights into impact of mass gatherings and AMR post
🔗 Register: www.targetamr.org.uk/hdrevents/ta...
Excellent talk from Jay Vornhagen on colonization success outcomes of Klebsiella pneumoniae.
So nice to see (micro)aerobic vs anaerobic environments considered. ABX model at the moment, but will be great to see if same principles apply to gut colonization models in metabolic health.
⌛Last call to submit your abstracts for #GAMRIC2026. Submissions close at 12 noon CEST tomorrow, 10 April 2026. We look forward to your submissions! https://ow.ly/feWe50YEX8H
💡You can also check out the GAMRIC preliminary programme now available! https://ow.ly/w2AB50YEX8F
#IDSky #clinmicro #AMR
Our ms on re-sampling 4 years apart vibrio phage in natural environments is now out with some improvements. First, clearer evidence of cryptic population dynamics between phage and vibrio, presumably because of genetic diversity. www.nature.com/articles/s41...
My lab at Pitt is looking for a Research Scientist to help us make phage therapy for patients with antibiotic-resistant infections. Please share and apply! cfopitt.taleo.net/careersectio...
Hand interacting with a digital interface displaying AI and data nodes, inviting microbiology community to join a new AI survey.
Artificial Intelligence in microbiology... where do you stand? We'd love to hear your thoughts in our new survey below.
Find out more about our new survey: https://microb.io/41bzWqG
Take part in the survey: https://forms.office.com/e/hvKeBzFhke
#AI #artificialintelligence
Hey #AMR people this one is for you!
Antimicrobial susceptibility testing in petri dish. AMR stock photo ©iStock/Md Saiful Islam Khan
🧬 Effective AMR action needs joined-up surveillance.
This workshop report outlines priorities for a UK National One Health AMR surveillance system.
🔗 https://doi.org/10.1099/jmm.0.002099
#KOAMR #KnockingOutAMR #OneHealth
The podcast all about the body’s defenders against disease!
New Immune episode 102: Living longer without B cells
Have you listened to the #MVIFconversations podcast?
There is a new episode where @cpavloud.bsky.social and I talked to @merenbey.bsky.social about open source, mentoring, and believe me it's a GREAAAT one!!
Apply to be an editor at an ASM Journal! Open call for editors at mBio, mSphere, mSystems, and Microbiology Spectrum. This is a very fulfilling way to share your expertise and give back to our society journals. @asm.org journals.asm.org/asm-call-for...
Messed around and ended up building a shiny app implementing rSalvador that my undergraduate lab can use to calculate mutation rates for their Luria-Delbruck experiments without having to run R
surt-lab.shinyapps.io/mutation_rat...
Aquatic Bacterial Community Responses to Aquatic Contaminants Revealed by 16S rRNA Metabarcoding in Field‐Based Microcosms enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/... #jcampubs
Open postdoc position in my lab on HGT and interbacterial competition. We seek candidates with a PhD in microbiology (or related fields)+ strong 1st-author publications.
Curious, highly motivated, and dedicated team players ready to contribute fully are encouraged to apply. Details: tiny.cc/cz01101
There's a common misconception that zoonotic viruses require significant adaptation to jump from animals to cause human epidemics.
Not so 👇.
Further, we see clear signs of 1977 flu experiencing cell passage, prior to epidemic.
SARS-CoV-2? Business as usual.
www.sciencedirect.com/science/arti...
The diversity in microbes is breath-taking. Individual cells may not look like much under the microscope - they are just too tiny.
But when they form visible colonies on agar plates many bacteria and moulds grow in the most staggering display of colours and shapes.
#AgarArt #Easter 🧫🦠🔬🐰🥚
Does anyone have examples of their own or others of how to best structure a GitHub repository for a scientific peer-reviewed manuscript?
#Science 🧪
One of my favorite parts about being an amateur biologist is the freedom some academics feel when talkin with me about biology ideas. I want to offer space to pure nerding. The topics and ideas in this space do good things to my brain and I chase that daily. Thanks for the warmth.