At #Bioiron impromptu dinner with 26 people at a wonder Persian Restaurant in Montreal with @hosseinardehali.bsky.social @suzcloo.bsky.social @manciaslab.bsky.social @ironresearchlab.bsky.social

Congratulations to Dr @lynnefaherty.bsky.social on the successful defense of her Thesis last Friday! Can’t wait to see what you do next Dr Faherty!

Endothelial-driven TGFβ signaling supports lung interstitial macrophage development from monocytes Endothelial Tgfβ1 shapes the development and functional identity of lung interstitial macrophages.

#WeekendRead! #EveryCellIsAnImmuneCell! Peng Bai Marichal &co show @ Science Immunology that endothelial cells produce TGFb to differentiate monocytes into #lung interstitial macrophages preventing aging & fibrosis
www.science.org/doi/10.1126/...

Bacterial pneumonia induces senescence in resident alveolar macrophages that are outcompeted by monocytes @cp-cellreports.bsky.social
www.cell.com/cell-reports...

Very productive visit from ERC President Maria Leptin - on the same page as our Taoiseach and Minister for Science when it comes to the need for increased funding for science in Ireland and Europe and ERC independence

Iron absorption, storage and conservation in the body

"Screening, diagnosis, and treatment of adults with absolute iron deficiency without anemia and iron-deficiency anemia."

jamanetwork.com/journals/jam...

Transcriptional activation of regenerative hematopoiesis via microenvironmental sensing - Nature Immunology Itkin et al. identify a role for Fli-1 in hematopoietic stem cell activation during regenerative hematopoiesis. They show that Fli-1 coordinates hematopoietic stem cells to stimulate niche-derived Not...

Congrats Rafii Lab @weillcornell.bsky.social ! Fli-1, a transcription factor that coordinates the two-way relationship between hematopoietic stem cells & angiocrine factors supplied by the vascular niche: a new paradigm in the physiology of hematopoiesis?
www.nature.com/articles/s41...

In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion.

Learn more in this week's issue: scim.ag/3FA3Ygq

Are you an ECR, submit an abstract with a chance to be selected for a talk!

Regenerating the lung - a multidisciplinary approach to combat COPD? - 6-7 NOVEMBER, 2025 - ERS Respiratory Channel To take part in this event, you must register in advance. REGISTER NOW 6-7 November, 2025 | Prague, Czech Republic   Organisers: M. Lehmann, S. Cloonan Faculty: S. Cloonan, T. Conlon, ...

For more information and how to register here 👇 channel.ersnet.org/media-113720...

Are you a basic researcher exploring COPD disease mechanisms, a translational scientist developing new COPD therapies, or a clinician seeking to improve patient outcomes, join myself and @mareikelehmann.bsky.social in Prague Nov 6-7 2025 for an ERS Research Seminar in collaboration with COPDiNet.

Heterogeneous human AM subsets have counterparts in mice! Nice work from @claudjak.bsky.social lab

The evolutionary tug-of-war of macrophage metabolism during bacterial infection The function and phenotype of macrophages are intimately linked with pathogen detection. On sensing pathogen-derived signals and molecules, macrophage…

One of my favorite topics right now! Very nice review on The evolutionary tug-of-war of macrophage metabolism during bacterial infection from @timsparwasser.bsky.social

read here 👇
www.sciencedirect.com/science/arti...

Macrophage peroxisomes guide alveolar regeneration and limit SARS-CoV-2 tissue sequelae Peroxisomes are vital but often overlooked metabolic organelles. We found that excessive interferon signaling remodeled macrophage peroxisomes. This loss of peroxisomes impaired inflammation resolutio...

Macrophage peroxisomes guide alveolar regeneration and limit SARS-CoV-2 tissue sequelae | Science www.science.org/doi/10.1126/...