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Posts by Tim Craggs

Filming equipment in the lab at Exciting Instruments HQ. Lots of cool kit everywhere.

Filming equipment in the lab at Exciting Instruments HQ. Lots of cool kit everywhere.

Something is happening at @ei-science.bsky.social HQ…

Can’t wait to show you all!

But I’m going to have to - won’t be long now.

1 month ago 2 0 0 0
Selfie of me on my way to the car - wearing my Exciting Instruments stash

Selfie of me on my way to the car - wearing my Exciting Instruments stash

Great session with the Masters students today @unisheffieldlib.bsky.social getting them all set up on @linkedin.com and more importantly here on @bsky.app

Please do give them a follow when you see them posting on here - part of their ‘homework’ this week ;)

Just posting on my way out…

1 month ago 2 0 0 0

Good to have you here!

1 month ago 2 1 0 0
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👀 At #BPS but haven’t stopped by booth 401 yet? Meet the team to discover how you can unlock the ultimate #single-molecule resolution at your benchtop, generating high-impact insights into #biomolecular interactions and dynamics. See you there! @biophysicalsoc.bsky.social #biophysics #lifescience

1 month ago 6 4 0 0
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🚀 Big news from @timcraggs.bsky.social x #BPS2026: meet the new EI-FLEX Pro! Automated alignment + focus, real-time analysis with publication-ready plots, modular upgrade to 96/384 wells, no darkroom or optical table, compact benchtop. Meet us at booth 401 or get in touch for a demo! #singlemolecule

2 months ago 19 6 0 1
Preview
Kinesin-1 is highly flexible and adopts an open conformation in the absence of cargo Kinesin-1 is an essential anterograde microtubule motor protein. The core kinesin motor is a homodimer of two heavy chains; N-terminal motor domains hydrolyse ATP and walk along microtubules, whilst a...

I'm a bit late with this, but awesome to see it out in the wild! A real tour de force from @dozenoaks.bsky.social @timcraggs.bsky.social An amazing example of why we need to think more about flexibility in our biological questions! www.cell.com/iscience/ful...

2 months ago 16 4 0 0
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New paper out!

i-Motif, not G-quadruplex, stability regulates insulin expression - published in @narjournal.bsky.social

Team effort driven by Dr Dilek Guneri supported by Dr Chris Morris, @timcraggs.bsky.social, @yiliangding.bsky.social and Prof Steve Smith

academic.oup.com/nar/article/...

2 months ago 11 5 1 0
Video

Congrats to Jamie et al! Our latest @york.ac.uk work dissecting the structural landscape of the Rep Helicase is now out in Nucleic Acids Research! 🧬🔬
@timcraggs.bsky.social @agnesnoy.bsky.social @bpsiyork.bsky.social @dr-mahmoud.bsky.social @single-mole.bsky.social
👇
tinyurl.com/bdznxur3

2 months ago 18 10 0 0

🗣️ Keynote Speaker: @sulianamanley.bsky.social

👥 Mentoring Session: Careers Across Biophysics featuring @valdavinson.bsky.social @timcraggs.bsky.social @sulianamanley.bsky.social @esisamakis.bsky.social

📈 Selected talk and poster presenters: You!

☀️ Please repost, share and we'll see you in June!

2 months ago 5 3 0 1
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Join Kuang and @timcraggs.bsky.social on 20th November to discuss his findings in more detail as part of our next Exciting Seminar - 'Mapping the global conformation of the Rag GTPase heterodimer with single-molecule FRET' > us06web.zoom.us/meeting/regi... 🧵 4/4

#structuralbiology #biophysics

5 months ago 2 2 0 0
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Can't decide if you like Biochemistry, Chemistry or Biophysics? Do all three! The bonus? You get to learn advanced biophysics with Prof Sarah Harris and @timcraggs.bsky.social and be exposed to the dynamic environment of @ei-science.bsky.social
Application information:
lnkd.in/eW9VxNBW

5 months ago 1 2 0 0
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Opening the London Stock Exchange - that’s all…

5 months ago 9 1 0 0
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📢 Our Exciting Seminars are back! Join @timcraggs.bsky.social & @shenk0128.bsky.social on Nov 20 for 'Mapping the global conformation of the Rag GTPase heterodimer with single-molecule FRET' > us06web.zoom.us/meeting/regi...

#biophysics #lifescienceevent #molecularmedicine #biochemistry #smfret

5 months ago 1 1 0 0
The entrance lobby for the new Exciting Instruments facility - with cool 3D logos and reflections in the window an interesting way around!

The entrance lobby for the new Exciting Instruments facility - with cool 3D logos and reflections in the window an interesting way around!

Love the optics here - see the reflection!

We are welcoming a lot of people to @ei-science.bsky.social getting great data on their own biological systems for prelim data for grants.

It’s nice to have a greta space to welcome them to!

Is there an #smFRET experiment you’d like to try? Ping me here!

5 months ago 8 0 0 0
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🔬Want to develop a blood test for dementia? A fully funded PhD position is available in our lab to probe and detect single molecules! Join our team @york.ac.uk
! Find out more & apply by 4th Dec:

tinyurl.com/yt36p9tx

@ybri-uoy.bsky.social @ei-science.bsky.social @timcraggs.bsky.social

5 months ago 3 4 1 0
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🚀 Since spinning out in 2021, our journey has been an Exciting one! Thrilled to see our CEO & founder @timcraggs.bsky.social named Entrepreneur of the Month by Insider Magazine. Read Tim’s comment below and the article here 👉 flickread.com/edition/html...

#entrepreneur #singlemolecule #sheffield

6 months ago 8 1 0 0
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Discover how single-molecule fluorescence reveals transient DNA–protein interactions, kinetics and conformational changes, and more. Meet @timcraggs.bsky.social & Paul Wheeler at next week’s events - email info@excitinginstruments.com
to schedule! #biophysics #smfret #fcs

7 months ago 0 1 0 0
What is single-molecule FRET?
What is single-molecule FRET? YouTube video by Exciting Instruments

What is single-molecule FRET? Watch
@timcraggs.bsky.social
explain how this technique measures nanometer-scale distances and captures single-molecule conformations - youtu.be/BpCsTVJkQyE #structuralbiology #moleculardynamics #discovery #smFRET

7 months ago 5 2 0 0

🙌 Excited to share that our CEO @timcraggs.bsky.social has been elected to @biophysicalsoc.bsky.social alongside Robert Best, Tanja Mittag & Kandice Levental. Congrats also to Enrique M. De La Cruz, elected President-elect!

#biophysics #lifescience #biophysicalsociety

8 months ago 9 3 0 0
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Looking forward to my first meeting council meeting at what could probably be my 10th annual meeting (and that only because for a long time I favoured the west coast years…)

8 months ago 0 0 1 0
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Holiday time! So good to recharge with family…

8 months ago 4 0 1 0

Congrats Rita - awesome!

8 months ago 2 0 1 0
Lecturer in Biophysics, Education Focused The incumbent will contribute to undergraduate teaching in Biophysics and across related disciplines within the School of Biomedical Sciences. Some responsibilities include preparing and delivering le...

🚨Job Alert: My department in UNSW Sydney is recruiting a teaching-only Lecturer in Biophysics. The lecturer will play a key role in the pedagogical development and delivery of courses and practicals in the new undergraduate (BSc) major in #Biophysics that we are launching from 2026. #AcademicBsky 🧪

8 months ago 26 21 0 1
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🤔 What if we could detect disease from a single molecule before symptoms even appear? This isn’t just innovation. It’s a shift in how we understand, detect, and prevent illness. Molecular insights are unlocking a new era in human health. #innovation #lifescience #biophysics

8 months ago 2 2 0 0

Come on England! 🏴󠁧󠁢󠁥󠁮󠁧󠁿

8 months ago 1 0 1 0

Come on England!! Always make is wait - but what a result!

8 months ago 0 0 0 0

Are you a @biophysicalsoc.bsky.social member? Vote in the 2025 election by 01/08! @timcraggs.bsky.social is nominated as Industry Rep. We encourage everyone to vote for this important cause, regardless of who you're voting for 🙂 www.biophysics.org/elections/bp... #biophysics #lifescience

9 months ago 5 4 0 0

Voting in the KPMG Private Enterprise Tech Innovator in the UK competition is open!

Show Exciting Instruments - and Yorkshire and the North East - your support by voting below 👇

app.sli.do/event/dkwYDn...

#innovation #startups #deeptech #yorkshire #sheffield

9 months ago 2 2 0 0
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Forget what you think you know about single-molecule fluorescence spectrometry instruments!

Introducing the EI-FLEX...

Find out more and request a tech spec > bit.ly/45AqRLv

#singlemolecules #biophysics #smfret #fcs #innovation

9 months ago 2 2 0 0
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The antihero in my story “Crisis Actors” uses cylindrical mirror anamorphism as an “encryption” technique [he’s not very bright], but I’d never seen it done with 3D objects rather than just flat images until I stumbled on this article about the sculptor Jonty Hurwitz.

10 months ago 66 8 1 1