A new study by Runfeng Lin & Sebastian Ahnerton from Cambridge University on the application of Circuit Topology in Protein Science:

"Millisecond Prediction of Protein Contact Maps from Amino Acid Sequences"
www.biorxiv.org/content/10.6...

#ChemSky #Topology #StructuralBiology #Bioinformatics

🔗 Lubricin’s Mucin Domain Has Strong Polyproline Type II Helical Character. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0021 📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

🔗 Lubricin’s Mucin Domain Has Strong Polyproline Type II Helical Character. Computational and Structural Biotechnology Journal. DOI: doi.org/10.34133/csb...

📚 CSBJ: spj.science.org/journal/csbj

#StructuralBiology #ProteinScience #Biophysics #ComputationalBiology #Osteoarthritis #Glycoproteins

Custom dictionary support is available in the PDBe mmCIF validator:

VS Code: set dictionary path in settings

Python script: pass dictionary path via CLI

#mmCIF #PDB #Bioinformatics #StructuralBiology

Aromatic π-Stacking Stabilizes an α-Helical SARS-CoV-2 MPER Peptide that Mimics the Post-Fusion Spike and Enables Potent Antiviral Activity | ChemRxiv Membrane fusion between SARS-CoV-2 and host cells is mediated by the spike protein and involves the membrane-proximal external region (MPER), a tryptophan-rich sequence implicated in viral entry. Here, we investigated the feasibility of MPER-derived ...

Excited to share a new preprint from our group @chemunicologne.bsky.social @unicologne.bsky.social!

chemrxiv.org/doi/full/10....

Big thanks to our collaborators at University of Florence!

#NMR #StructuralBiology #AntiviralResearch #Peptides #SARSCoV2 #DrugDesign #Biophysics #Collaboration

Four scientists at dinner

It was delightful to have a chance to catch up with @nozomi-ando.bsky.social during her visit to UB and hear about the amazing work happening in her group @andolab.bsky.social! The new work untangling allostery in ATCase is🔥!

#structuralbiology #biochemistry #allostery

Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity - Nature Cas9 structures explain topology sensing and off-target activation.

Here is a strong candidate for the coolest-looking #cryoEM structure of 2026! 🤩

Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity

https://doi.org/10.1038/s41586-026-10255-7

#StructuralBiology

Postdoc in Computational Biology & Machine Learning - Academic Positions (Academic Positions)

Job of the day · 26.03.26
Postdoc in Computational Biology & Machine Learning - Academic Positions (Academic Positions)
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Purple Biotech Announces AI Collaboration with Converge Bio to Accelerate Development of its Next-Generation Tri-Spec...

Industry news of the day · 26.03.26
Purple Biotech Announces AI Collaboration with Converge Bio to Accelerate Development of its Next-Generation Tri-Specific Antibody Platform - Bitget
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

The algorithmic inversion of pharma - Express Pharma The algorithmic inversion of pharma    Express Pharma

AI news of the day · 26.03.26
The algorithmic inversion of pharma - Express Pharma
The algorithmic inversion of pharma    Express Pharma
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Paper of the day · 26.03.26
DynaBench: Dynamic data for the docking benchmark.
Protein-protein interactions are central to numerous cellular processes, including transport...
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Hiring Now: 636 Computational Biology Jobs in Boston, MA – Great Pay & Flexible Hours (March 23, 2026) - Indeed (Inde...

Job of the day · 25.03.26
Hiring Now: 636 Computational Biology Jobs in Boston, MA – Great Pay & Flexible Hours (March 23, 2026) - Indeed (Indeed Jobs)
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

JAA - Dove Medical Press JAA    Dove Medical Press

Industry news of the day · 25.03.26
JAA - Dove Medical Press
JAA    Dove Medical Press
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

How structural biology is reshaping tuberculosis research and treatment - Van Andel Institute How structural biology is reshaping tuberculosis research and treatment    Van Andel Institute

AI news of the day · 25.03.26
How structural biology is reshaping tuberculosis research and treatment - Van Andel Institute
How structural biology is reshaping tuberculosis research and treatment    Van...
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Paper of the day · 25.03.26
Integrative structural and physicochemical characterization of chalcone synthase enzymes from medicinal plants using AlphaFold, molecular dock...
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

🔗 Antibacterial Drug Discovery: Deep Learning Successes and Challenges through the Structural Biology Lens. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0008 📚 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj

🔗 Antibacterial Drug Discovery: Deep Learning Successes and Challenges through the Structural Biology Lens. DOI: doi.org/10.34133/csb...

📚 CSBJ: spj.science.org/journal/csbj

@sydney.edu.au @aaas.org #AntibioticResistance #DrugDiscovery #Bioinformatics #StructuralBiology #ComputationalBiology

Julia Mahamid, Ph.D. – Gottfried Wilhelm Leibniz Prizewinner 2026

Congratulations to Dr. Julia Mahamid on receiving the 2026 Gottfried Wilhelm Leibniz Prize! 🎉

Her pioneering work in cryo-ET is reshaping our understanding of how molecular architecture drives cellular processes and disease.

#teamtomo #LeibnizPrize #StructuralBiology #LifeSciences #Innovation

235 Artificial Intelligence jobs - Academic Positions (Academic Positions)

Job of the day · 23.03.26
235 Artificial Intelligence jobs - Academic Positions (Academic Positions)
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Recognizing the Right Time to Start Biologics in HS - Dermatology Times Recognizing the Right Time to Start Biologics in HS    Dermatology Times

Industry news of the day · 23.03.26
Recognizing the Right Time to Start Biologics in HS - Dermatology Times
Recognizing the Right Time to Start Biologics in HS    Dermatology Times
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Man uses ChatGPT and AlphaFold to build DIY mRNA cancer vaccine, saves dog - MSN Man uses ChatGPT and AlphaFold to build DIY mRNA cancer vaccine, saves dog    MSN

AI news of the day · 23.03.26
Man uses ChatGPT and AlphaFold to build DIY mRNA cancer vaccine, saves dog - MSN
Man uses ChatGPT and AlphaFold to build DIY mRNA cancer vaccine, saves dog    MSN
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Paper of the day · 23.03.26
AlphaFold3: A Transformer in Life Sciences.
The development of AlphaFold2 (AF2) marked a revolutionary milestone in the field of life sciences,...
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Millions of protein complexes added to AlphaFold Database shed light on how proteins interact Four-way collaboration brings together world-leading AI and biological expertise to make AI-predicted protein complex structures openly available to the global scientific community

17-Mar-2026
Millions of #protein complexes added to #AlphaFold Database shed light on how proteins interact

https://www.eurekalert.org/news-releases/1119736

#science #structuralBiology

Bioinformatics scientist salary in Lexington, MA - Indeed (Indeed Jobs)

Job of the day · 19.03.26
Bioinformatics scientist salary in Lexington, MA - Indeed (Indeed Jobs)
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Dyno Therapeutics Launches Dyno Psi-Phi, an Agentic AI Suite for Protein Binder Design, at NVIDIA GTC 2026 - Business... Dyno Therapeutics Launches Dyno Psi-Phi, an Agentic AI Suite for Protein Binder Design, at NVIDIA GTC 2026    Business Wire

Industry news of the day · 19.03.26
Dyno Therapeutics Launches Dyno Psi-Phi, an Agentic AI Suite for Protein Binder Design, at NVIDIA GTC 2026 - Business Wire
Dyno Therapeutics Launches Dyno Psi-Phi, an Agentic AI...
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Millions Of Protein Complexes Added To AlphaFold Database Shed Light On How Proteins Interact - astrobiology.com Millions Of Protein Complexes Added To AlphaFold Database Shed Light On How Proteins Interact    astrobiology.com

AI news of the day · 19.03.26
Millions Of Protein Complexes Added To AlphaFold Database Shed Light On How Proteins Interact - astrobiology.com
Millions Of Protein Complexes Added To AlphaFold Database Shed Light O...
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Paper of the day · 19.03.26
Design, Synthesis, Molecular Dynamics Simulations, and Biological Evaluation of PB2 Inhibitors as Anti-Influenza A Virus Agent.
Influenza A vir...
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

HCW Biologics Inc. Receives $7 Million Upfront License Fee from Beijing Trimmune Biotech for HCW11-006 Development an...

Industry news of the day · 18.03.26
HCW Biologics Inc. Receives $7 Million Upfront License Fee from Beijing Trimmune Biotech for HCW11-006 Development and Commercialization Rights - Quiver Quantitative
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1.7 Million Protein Complexes Added to AlphaFold Database - Labcompare 1.7 Million Protein Complexes Added to AlphaFold Database    Labcompare

AI news of the day · 18.03.26
1.7 Million Protein Complexes Added to AlphaFold Database - Labcompare
1.7 Million Protein Complexes Added to AlphaFold Database    Labcompare
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

Paper of the day · 18.03.26
Molecular Dynamics-Guided Design and Chemoproteomic Profiling of Covalent Kinase Activity Probes.
Covalent small molecule probes can be powerfu...
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#ProteinDesign #StructuralBiology #Bioinformatics #ProteinEngineering

AF2-mutation strategies expanding protein structure prediction—deepening AI’s role in therapeutic discovery
www.scienceopen.com/hosted-docum...
#AlphaFold #ProteinStructure #AIinBiology #StructuralBiology

Millions of protein complexes added to AlphaFold Database shed light on how proteins interact Four-way collaboration brings together world-leading AI and biological expertise to make AI-predicted protein complex structures openly available to the global scientific community.

#AlphaFoldDB now has binary protein complexes!

www.ebi.ac.uk/about/news/technology-an...

#AlphaFold #AlphaFold2 #StructuralBiology