GA4GH Global Alliance for Genomics & Health (GA4GH) is a policy-framing and technical standards organization, working together for responsible, voluntary & secure sharing of genomic & clinical data for…

Welcome to day one of the GA4GH 13th Plenary meeting. We are excited to welcome attendees and viewers from around the globe.

Our Plenary live stream starts in one hour. Visit the GA4GH YouTube Channel to tune in to today’s programme:

Adaptation is less accessible through mutations in promoters than in coding sequences when large effect sizes are needed Mutations within promoters and coding sequences are both involved in adaptation, but their relative contributions remain to be compared directly. Using the fungal enzyme cytosine deaminase, we examine...

Really excited to share our latest paper led by @simonaube.bsky.social. Fascinating results examining whether regulatory mutations can lead to adaptation as fast as coding mutations do. #mevosky #evobio #evoSky

www.biorxiv.org/content/10.1...

A circular phylogeny of Malawi cichlids with inversion frequencies indicated for different taxa as rings around the tree.

Check out our new paper about chromosomal inversions in Malawi cichlids! 🐟🧬

Available here without a paywall: hdl.handle.net/10067/214834... (click on the ‘Full text (open access)’ link).

Coalescence and Translation: A Language Model for Population Genetics Probabilistic models such as the sequentially Markovian coalescent (SMC) have long provided a powerful framework for population genetic inference, enabling reconstruction of demographic history and an...

Cool new paper on pop gen and machine learning:

www.biorxiv.org/content/10.1...

Reason number 4,517 (yes I'm counting) why @maizegdb.bsky.social is so awesome and we're so lucky as a community to have these folks. Also a great example of maize community sharing. UNPUBLISHED data already up on the community database showing conservation scores across the maize genome.

Maximizing meiotic crossover rates reveals the map of Crossover Potential - Nature Communications Meiotic crossovers enhance genetic diversity in sexually reproducing organisms. Here, the authors propose that the higher-order spatial organization of the meiotic chromosomes shapes sexual dimorphism...

Paper alert! #Meiosis4Ever

Maximizing meiotic crossover rates reveals the map of Crossover Potential

Juli Jing, Qiachao Lian and Stephanie Durand
www.nature.com/articles/s41...

We pushed meiotic crossover as much has we could, and had some surprises

A thread 👇

A 6000-year-long genomic transect from the Bogotá Altiplano reveals multiple genetic shifts in the demographic history of Colombia The hunter-gatherer gene pool of the Bogotá Altiplano was replaced by Central American ancestry at least 2000 years ago.

Researchers in #ScienceAdvances have uncovered a previously unknown genetic branch of ancient hunter-gatherers local to the Colombian land bridge.

Learn more: scim.ag/4mEsGNL

Thread with an email being sent to @asn-amnat.bsky.social @sse-evolution.bsky.social @systbiol.bsky.social members today calling for a Tri-society week of action for NSF:

Dear members:
The tri-societies (ASN, SSE,SSB) are running a ‘Week of Action for NSF’. Your engagement is crucial.

PhD Student in Evolution of Seasonal Camouflage The Department of Zoology at Stockholm University includes about 80 employeese, including Researchers, PhD students and administrative staff. Research and education at the department occurs in an inte

PhD position on Evolution of Seasonal Camouflage in my group. Fully funded 4 year position in Stockholm University and SciLifeLab! :-)

su.varbi.com/en/what:job/...

Infographic of five steps for preparing genomics data for AI, including cleaning, consistency, relevance, structuring, and labeling. 1. Clean the Data 2. Keep it consistent 3. Make it relevant 4. Structure your data 5. Label everything

Infographic outlining AI data management steps with icons and descriptive text. Transcribed Text: 6. Ensure data diversity 7. Balance your dataset 8. Make it accessible 9. Track its history 10. Scale up for robust AI training

Can #AI supercharge genomics research? Only if the data are ready 💻

Check out our top 10 tips to get your genomics AI-ready ⤵️

sangerinstitute.blog/2025/04/01/t...

Registrations for the #LivingData2025 are OPEN! 🥳 This joint conference in Bogotá will bring together members of the biodiversity networks with hundreds of scientists, researchers, practitioners, and experts from around the world. 🐸

Toward a Global Science of Conservation Genomics: Coldspots in Genomic Resources Highlight a Need for Equitable Collaborations and Capacity Building Advances in genomic sequencing have magnified our understanding of ecological and evolutionary mechanisms relevant to biodiversity conservation. As a result, the field of conservation genomics has gr...

So fun to see this lab project published! Conservation Genomicists we still have quite a lot of work to do!

Genetic diversity is key to restoring nature — Coalition for Conservation Genetics Find out how genetic diversity can be integrated into the EU’s Nature Restoration Regulations.

🚨New #policy research! A recent study explores how the #conservation of #GeneticDiversity can be integrated into the EU’s Nature Restoration Regulations & why safeguarding genetic diversity is key to ecosystem resilience🌿
Read more here: www.coalitionforconservationgenetics.org/resources-da...

The Idiot's Guide to Effective Population Size This is a reference manual for the elegant, yet hideously complex concept of effective population size (Ne), inspired by a classic, self-published manual of automotive repair ‘for the compleat idiot’...

Wow. This is sooo good. Echoing @urbanevol.bsky.social this user’s manual for Ne should be required reading for popgen and conservation genetics folks. onlinelibrary.wiley.com/doi/10.1111/...

Global meta-analysis shows action is needed to halt genetic diversity loss - Nature A comprehensive meta-analysis of global terrestrial and marine genetic diversity covering more than three decades of research demonstrates rapid loss of genetic diversity and identifies conservation i...

Out now in @nature.com! Our comprehensive meta-analysis of global terrestrial and marine genetic diversity demonstrates rapid loss of genetic diversity and identifies conservation interventions that could mitigate this process
www.nature.com/articles/s41...
🧪🌍🦤🧬
#consgen #PopGen

Comparison of allele frequency spectra for 3x coverage, with and without our bias model.

Our paper on fitting population genetic models to low-pass sequencing data is now out in Molecular Biology and Evolution! doi.org/10.1093/molb...

Romina Batista on LinkedIn: I am absolutely flattered to share our review paper:… I am absolutely flattered to share our review paper: https://lnkd.in/ePqhdHK7 Led by Dr. Camila Ribas! A collaborative/interdisciplinary work where we…

www.linkedin.com/posts/romina...

Fantastic team and workshop! Missing you all already. Best wishes 😊

Hi! I'd like to be added too, thanks!

Let´s form a community of conservation geneticists here - I started with some people I know, but there are likely to be many more... I can happily add them to this list
go.bsky.app/VMqVSAi

🤚

Could you please add me? Thanks!