Development of the fluorescent probe CenSpark for labeling centrioles and cilia - Nature Chemical Biology CenSpark is a dual-ligand fluorescent probe binding simultaneously inner and outer microtubule sites, a configuration unique to doublet and triplet microtubules, enabling selective live imaging of cen...

CenSpark story is now published in @natchembio.nature.com. We engineered a dual-ligand fluorescent probe to selectively "light up" centrioles & cilia. Massive thank to Pierre Gönczy, @lreymond.bsky.social and @ghatzopoulos.bsky.social for the guidance. Check it out 👉: doi.org/10.1038/s415...

If you haven’t tried BigVolumeBrowser yet, you should do it now!!

Cryo-electron microscopy scientist Join our team to contribute to the operation and innovation of state-of-the-art cryo-electron microscopes and empower groundbreaking research.

The newly established NeCEN Utrecht is looking for a #cryoEM scientist!

www.uu.nl/en/organisat...

Work with a new Krios 5 + pFIB and support cutting-edge life science research.

📍 Utrecht | 🗓 Apply by 30 April

Please share with your network!

How is expansion microscopy pushing beyond the original ~4× expansion limit, to unlock new ways to visualise biological structure at increasingly fine detail? Check out our review article "𝐁𝐞𝐲𝐨𝐧𝐝 𝟰×: 𝐩𝐚𝐭𝐡𝐰𝐚𝐲𝐬 𝐭𝐨 𝐡𝐢𝐠𝐡𝐞𝐫 𝐞𝐱𝐩𝐚𝐧𝐬𝐢𝐨𝐧 𝐟𝐚𝐜𝐭𝐨𝐫𝐬 𝐢𝐧 𝐞𝐱𝐩𝐚𝐧𝐬𝐢𝐨𝐧 𝐦𝐢𝐜𝐫𝐨𝐬𝐜𝐨𝐩𝐲" www.degruyterbrill.com/document/doi...

Nice! Gefeliciteerd!

Learnathon/hackathon on the development of ImgLib2/BigDataViewer based Fiji tools for dealing with large image data (survey) Hello all, There is an increasing number of new tools to work with image data. But for many life scientists, Fiji remains a very important platform when it comes to interactively working with image d...

We want to organize a learnathon to teach plugin development within #FIJI #scijava #imglib2 #BigDataViewer and other Big* parts of the Java ecosystem.
Please spread the word, and if you know someone who can be interested, forward them the link below forum.image.sc/t/learnathon...

Invasion and Metastasis - How cancer cells become invasive YouTube video by IMAGINE! microscopy

I collaborated with Peter Friedl's team, @jpassmore.bsky.social and @ekatrukha.bsky.social to make this short video on cancer cell invasion. Check it out! youtu.be/EH4vgUfr1jI?...

well, I would say it might be a relative old oil. Maybe the bottle was improperly closed for some time and this caused something?
I would anyway compare it to a new bottle. If it persists, contact Zeiss about it.

Should be stable til June it says…

We are very proud to present our newest paper on the role of Wnt signalling in abscission dynamics in stem cells! A brief thread to entice you to read Snježana’s exciting foray into signalling.

Smart microscopy: adaptive microscope control to improve the way we see life - npj Imaging npj Imaging - Smart microscopy: adaptive microscope control to improve the way we see life

Another interesting review on #SmartMicroscopy. 🔬https://www.nature.com/articles/s44303-026-00145-y#Sec1

Last year's disco on a ring-TIRF setup. (Objective removed)

+ BVB new release is coming in a week or so with an animation render feature. Still super buggy, but I am already testing it on silly examples (2/2)

Or his thesis: pure.tue.nl/ws/files/469...

... The tool accurately
identifies areas of high density, assessing the quality of shots, and approximates the balance of
play during a match. My contributions have yielded insights into the momentum and balance
of power between the teams at any given moment during a match."

From the developer's linkedin page:
"Developed a sophisticated visualization tool — the Wave — utilizing spatiotemporal data
to elucidate and to help comprehend the complex events in a soccer match. ...

‘Wave’: the match at a glance Computer Science student Marijn Grootjans graduated today on his platform called ‘Wave’ which gives an at-a-glance representation of a soccer match.

I suspect this: www.tue.nl/en/news-and-...

Awesome

Blaschkakabinet De blaschka-modellen zijn de pareltjes van glas in de wetenschap. Deze natuurgetrouwe glazen modellen van o.a. kwallen, zeeanemonen, wormen en slakken zijn meer dan honderd jaar oud.

Are you aware of the collection in the Utrecht University Museum? umu.nl/blaschkakabi...

We are considering acquiring the PlayerOne Ares M for one of our upright microscopes as a very affordable option. As the camera has been running since March 2025 in your facility, I was wondering: would you still recommend it?

One of the perks of living in San Francisco is free visits to the Photonics West trade show. Sharing my notes for those missing out: nicost.github.io/microscope-t...

what is the working distance?

If you have time tomorrow, join my online talk about LLS/single molecule/microtubules and 3D data at @bioimagingna.bsky.social user group (18:00 CET for Europe).
I hope I manage to fit 25 movies into 20 cohesive slides and connection will be ok.

Last project of the year: self blinking JF635 + lattice light sheet + #BigVolumeBrowser to deskew both volume and localization data (and render)
@zeiss-microscopy.bsky.social

Bored over the holidays? Give our new preprint on how #microtubule lattice alteration by taxols can regulate #RhoA #signalling via GEF-H1 a read!

Perhaps a new mechanism of action for taxol #chemotherapeutics during interphase.

www.biorxiv.org/content/10.6...

Happy holidays ✨🎄

Pfffffff. Chains of transformations are hard. It took me two releases to get the live deskew slider right and looking ok (hopefully) #bigvolumebrowser

Amen.

We like our microscopes…

My lab is hiring a postdoc (ERC funded)! If you're interested, get in touch!

Now published with peer-review-induced improvements in Biomedical Optics Express: doi.org/10.1364/BOE.579043

We continue to recommend the use of Sarstedt lumox dishes for ease of use and high-quality imaging performance: bsky.app/profile/jame...