Clinical development of cancer vaccines - Nature Medicine This Review highlights insights from recent clinical trials and discusses critical factors for optimizing cancer vaccines, with a focus on proxies for vaccine efficacy, neoantigen selection, modular p...

New Review on #CancerVaccines: John Haanen and colleagues highlight insights from recent clinical trials and discuss critical factors for optimization, with a focus on proxies for efficacy, #neoantigen selection, modular platforms and early intervention
www.nature.com/articles/s41...

I have stage four cancer – there will be no cure, but death isn’t necessarily imminent: this is how it feels to live in the long middle When you are cured, the world cheers; when you are dying, it mourns. But when you are simply maintaining, the world is at a loss

"I have stage four cancer – there will be no cure, but death isn’t necessarily imminent: this is how it feels to live in the long middle" www.theguardian.com/society/2026...

Why clinical trials are leaving the US—and Asia and Australia are welcoming them Disruption and uncertainty in the US are leading many clinical trials to consider other countries for participation. Jennifer Lutz , Neha Bhatt , and Flynn Murphy report on the changing landscape—and ...

Disruption and uncertainty in the US are leading many clinical trials to consider other countries for participation.

How is the research landscape changing—and why are some places making a major play for trials fleeing the US?
https://bit.ly/3ZFoLG4

REMINDER: Call for nominations for @cancersociety.bsky.social Advisory Council on Research (ACOR).

We’re looking for #researchers and people with lived or living #cancer experience to join our ACOR and help guide #research programs and priorities.

Deadline is Feb 27.

Nominate here: is.gd/sMS7iN

Don’t talk science, play science: translate your data into music to improve its reach Data sonification helps researchers to build connections and communicate their science to a broader audience.

Don’t talk science, play science: translate your data into music to improve its reach www.nature.com/articles/d41...

@cancersociety.bsky.social -funded research is changing how people with #cancer are treated worldwide. We’re proud to see @myesmo.bsky.social #ClinicalPracticeGuideline update recommending structured exercise for people with #ColonCancer.

Learn more about this @cctg.bsky.social trial: is.gd/ojV6cY

Canada’s largest cancer research tumour bank moves to new home at KHSC Decades of cancer research—and thousands of patient tumour samples — now have a new home at Kingston Health Sciences Centre (KHSC), and this state-of-the-art space will change how researchers study ca...

Canada’s largest cancer research tumour bank moves to new home at KHSC kingstonhsc.ca/cancer-care/...

Should professors be forced to retire? Some universities are implementing a mandatory retirement age for academics. Will it help young researchers to get permanent positions?

Should professors be forced to retire? www.nature.com/articles/d41...

Cellular senescence in precancer lesions and early-stage cancers Cellular senescence plays dual roles in precancer lesions: initially serving as a tumor-suppressive barrier within the epithelial compartment and later contributing to a pro-tumoral precancer tissue microenvironment (PreTME) via a sustained, paracrine secretome known as senescent-associated secretory phenotype (SASP). This commentary highlights the role of senescence across various PreTME cell types, explores emerging pharmacologic and lifestyle interception strategies, and outlines current challenges for advancing biomarkers and clinical translation.

Cellular senescence in precancer lesions and early-stage cancers

Discovery of predictive biomarkers for cancer therapy through computational approaches. Great review in
@natrevclinonc.nature.com from international team including Canadian representatives from @vectorinstitute.ai and @pmresearch-uhn.bsky.social. www.nature.com/articles/s41...

Intake of food additive preservatives and incidence of cancer: results from the NutriNet-Santé prospective cohort Objective To investigate the association between intake of food additive preservatives and cancer incidence in a large prospective cohort. Design Prospective cohort. Setting French NutriNet-Santé co...

Intake of food additive preservatives and incidence of cancer: results from the NutriNet-Santé prospective cohort in @bmj.com
www.bmj.com/content/392/...

Bridging the gap in lung cancer: A comprehensive global strategy for change Unless greater awareness inspires action, lung cancer will become the next global public health emergency. Despite improvements in screening, diagnosis, and treatments, more must be done because globa...

Bridging the gap in lung cancer: A comprehensive global strategy for change www.ejcancer.com/article/S095...

Enhancing Clinical Cancer Research Through Sharing of Data and Biospecimens This Special Communication describes obstacles to sharing data and biospecimens and proposes strategies to enhance access and collaboration.

Enhancing Clinical Cancer Research Through Sharing of Data and Biospecimens jamanetwork.com/journals/jam...

I hope someone draws this wonderful story about Tom Stoppard's Arcadia and the power of the arts to help us see things differently, to the attention of our Education Secretary. Do read it, it will lift your spirits.

Canadian Prostate Cancer Trends in the Context of PSA Screening Guideline Changes. More prostate cancer cases diagnosed at stage 4 in recent years. www.mdpi.com/3612656

The software we deserve: Vibe coding the future of health technology - Healthy Debate Vibe coding represents a potentially transformative approach to health informatics.

Great piece on @healthydebate.bsky.social on the potential of vibe coding to transform health informatics and improve health system efficiency. healthydebate.ca/2025/11/topi...

What is prostate cancer and how is it diagnosed in the UK? As David Cameron receives treatment and backs calls for an NHS screening programme, we look at the disease and its treatment

David Cameron receives treatment and backs calls for NHS screening. More than 100 MPs urge Streeting to approve prostate cancer screening. Helpful explainer from @theguardian.com.
www.theguardian.com/society/2025...

Microbubble-enhanced transcranial focused ultrasound with temozolomide for patients with high-grade glioma (BT008NA): a multicentre, open-label, phase 1/2 trial MB-FUS plus temozolomide is a safe combinatorial therapeutic approach for individuals with high-grade glioma, with the potential to improve survival and enable non-invasive plasma biomarker-based dise...

Microbubble-enhanced transcranial focused ultrasound with temozolomide for patients with high-grade glioma (BT008NA): a multicentre, open-label, phase 1/2 trial in @thelancetoncol.bsky.social. Exciting work led by team from @sunnybrookhsc.bsky.social
www.thelancet.com/journals/lan...

A deliverable national cancer control plan for the UK: lessons from abroad and the need for discipline at home - The Lancet Oncology www.thelancet.com/journals/lan...

People with some cancers live longer after a COVID vaccine mRNA vaccines seem to boost the effectiveness of an immune therapy for skin and lung cancer ― in an unexpected way.

mRNA vaccines seem to boost the effectiveness of an immune therapy for skin and lung cancer ― in an unexpected way in @nature.com www.nature.com/articles/d41...

#ESMO25: 177Lu-PSMA-617 with ADT plus ARPI showed PFS benefit in hormone-sensitive #ProstateCancer (#HSPC) but no improvement seen with 177Lu-PSMA-617 vs docetaxel in castration-resistant prostate cancer (#mCRPC) after ARPI.
#ESMODailyReporter ➡️ https://ow.ly/2C0e50XeAoj

Men with BRCA1 and BRCA2 mutations should get annual #ProstateCancer screening.

The IMPACT trial finds BRCA1 carriers are 3 times more likely to have aggressive prostate cancers than non-carriers.

Results from the international trial shared at @myesmo.bsky.social

www.icr.ac.uk/about-us/icr...

Cell-free DNA fragmentomics in cancer The analysis of cell-free DNA (cfDNA) fragmentation patterns, known as “fragmentomics,” has opened new opportunities in noninvasive cancer diagnostics. In this Review, Tsui et al. explore the exciting...

“Fragmentomics” has opened new opportunities in noninvasive cancer diagnostics. Excellent review in @cp-cancercell.bsky.social by Dennis Lo of #CUHKMedicine www.cell.com/cancer-cell/...

Rishi Sunak: Prostate cancer screening could 'save countless lives' The former PM is among those in favour of targeted screening for men most at risk, but some medical experts are sceptical.

"I find it very, very difficult to think that just because people have a certain kind of privilege they can be treated. It's unfair," Sir Steve McQueen in a new call for targeted prostate cancer testing in the UK www.bbc.com/news/article.... We need to do better in Canada too.

All fluffed up: why modern balls are sparking injury worries and frustration in tennis Daniil Medvedev is one of a growing number of leading players who say that the balls have become unpredictable and are affecting their game

All fluffed up: why modern balls are sparking injury worries and frustration in tennis. Great piece by @tumcarayol.bsky.social. Not all tennis balls are equal. www.theguardian.com/sport/2025/o...

Quantitative assessment of the radon (222Rn) decay product 210Pb in human toenails as a sensitive measure of personalized long-term radon gas exposure history Lung cancer mortality can be lowered through early-diagnostic screening of people demonstrating a ≥1.5 % 6-year risk of tumor development. However, ma…

Quantitative assessment of the radon (222Rn) decay product 210Pb in human toenails as a sensitive measure of personalized long-term radon gas exposure history. www.sciencedirect.com/science/arti... Important research from @ucalgarymed.bsky.social funded by @cancersociety.bsky.social

Sure, Ultra-Processed Foods Are Bad. But How Does That Help Anyone? | The Walrus Nutrition panic distracts from the policies that make healthy eating a privilege

Another great piece by @caulfieldtim.bsky.social this time on UPFs - however we’re defining them thewalrus.ca/sure-ultra-p...

Niraparib and abiraterone acetate plus prednisone for HRR-deficient metastatic castration-sensitive prostate cancer: a randomized phase 3 trial - Nature Medicine In the randomized phase 3 AMPLITUDE trial, patients with HRR-deficient mCSPC experienced longer progression-free survival when they were treated with niraparib and AAP compared to placebo and AAP.

Niraparib and abiraterone acetate plus prednisone for HRR-deficient metastatic castration-sensitive prostate cancer: a randomized phase 3 trial in @natmed.nature.com www.nature.com/articles/s41...

Webinar: Biology to Prevention Award co-funded with Canadian Cancer Society Join our webinar on 28 October to learn about this new partnership and how to apply for co-funding through the Biology to Prevention Award

New transatlantic cancer research funding!

We're partnering with @ccsresearch.bsky.social to co-fund our Biology to Prevention Award, doubling the funding for collaborative UK and Canadian prevention research teams.

Join our webinar on 28 October at 14:00 GMT to learn more: cruk.ink/46yjOBX